Analysis of newly discovered TRPV1 molecule functions in osmoreception

About This Project

Japan Grant Number
JP16K08073 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
16K08073
Research Category
Grant-in-Aid for Scientific Research (C)
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Biological Sciences > Agriculture > Animal life science > Integrative animal science
Research Institution
  • Tottori University
Project Period (FY)
2016-04-01 〜 2019-03-31
Project Status
Completed
Budget Amount*help
4,940,000 Yen (Direct Cost: 3,800,000 Yen Indirect Cost: 1,140,000 Yen)

Research Abstract

Cellular functions and molecular distribution of TRPV1-related molecules, which are known as the key molecule for central osomolality sensing. mRNAs for TRPV1_SON and TRPV1 were both expressed in the ventral vasopressin-neuron region of the supraoptic nucleus. When expressed in HEK293 cells either alone or in combination with TRPV1, TRPV1_SON did not show s response to osmolality increase.

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