Challenging the Production of Super-Female Chickens by Exploiting the 'Flexibility' of Avian Sex Determination Mechanisms

KAKEN

About This Project

Japan Grant Number
JP25K22423 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
25K22423
Research Category
Grant-in-Aid for Challenging Research (Exploratory)
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Research Institution
  • Kyushu University
Project Period (FY)
2025-06-27 〜 2028-03-31
Project Status
Granted
Budget Amount*help
6,240,000 Yen (Direct Cost: 4,800,000 Yen Indirect Cost: 1,440,000 Yen)

Research Abstract

採卵鶏のオス雛は世界で年間70億羽が殺処分されており、動物福祉と経済の重大な課題となっている。本研究は、鳥類特有の性決定機構のゆるさ（=柔軟性）を活用し、アロマターゼ阻害剤により遺伝的メスを機能的オスに性転換させる。この性転換オスが産生する精子を利用してWW個体（超メス）を作出し、超メスと正常オスの交配によりメスのみを産む系統の確立に挑戦する。「オスを産まない」という革新的発想でオス雛殺処分問題の根本的解決を目指す。

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