ラットの組織及び下肢骨格筋重量に対する脱トレーニングの影響

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  • ラット ノ ソシキ オヨビ カシ コッカクキン ジュウリョウ ニ タイスル ダツトレーニング ノ エイキョウ
  • Effects of Long Term De-training on the Each Tissue and the Skeletal Muscle Weight in Rat

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The effect of long term de-training on the each tissue and skeletal muscle weight was investigated in the female Fischer344 rats. The animals were divided into four groups: 23-week-old control (23C)，23-week-old trained (23T) ， 77-week-old control (77C) and 77-week-old de-trained (77DT). Animals in group 23T and 77DT were trained with treadmill running （～77%VO2max， 60 min/day and 5 days/wk) for 10 weeks. The de-training period was 53 weeks. The results showed that the relative heart weight in group 23T was significantly higher than group 23C，77C and 77DT. The relative fat pad (inguinal and retroperitoneal) weight in group 23T was significantly lower than group 23C. There was no significant difference in the relative liver weight among all groups. The relative hind limb muscle weight， except lateral gastrocnemius， in group 77-week-old was significantly lower than group 23- week-old. However， The relative lateral gastrocnemius muscle weight in group 77-week-old was significantly higher than group 23-week-old. The relative hind limb muscle weight， except extensor digitorum longus and soleus in group 23T， was significantly higher than group 23C. There was no significant difference between group 77C and 77DT in hind limb muscle weight. These results indicate that training effects was lost for a long-term de-training period on each tissue and skeletal muscle weight in rats.

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