Antioxidants encapsulated milk-derived exosomes for functional food development

DOI 機関リポジトリ (HANDLE) PDF Web Site PubMed 参考文献35件 オープンアクセス

書誌事項

タイトル別名
  • Antioxidants encapsulated milk‑derived exosomes for functional food development
公開日
2023-02-04
資源種別
journal article
DOI
  • 10.1007/s44211-023-00278-9
公開者
The Japan Society for Analytical Chemistry

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説明

Reactive oxygen species are known to be involved in various diseases, and antioxidant ingredients are expected to essentially prevent diseases and contribute to improving health. However, antioxidants are easily degraded by enzymes before being absorbed in the intestine, so a means of transport that prevents their degradation in the body is necessary. Exosomes, which play an important role in communication between individual cells, have attracted attention as a new transport carrier of miRNA and DNA, but not yet fully exploited in food research. More recently, exosomes extracted from bovine milk began to be widely used as a cost-effective transport carrier not in clinical medicine but also in functional food materials. To develop practical applications as carriers for functional foods, systematic studies are necessary to clarify the introduction efficiency and the properties of encapsulated substances. In this study, we applied electroporation and incubation to encapsulate antioxidants into the exosomes and studied the encapsulation efficiency into the exosomes and the anticancer activity.

収録刊行物

  • Analytical Sciences

    Analytical Sciences 39 705-712, 2023-02-04

    The Japan Society for Analytical Chemistry

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