書誌事項
- タイトル別名
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- ショウレイ ホウコク(ダイ28カイ トクシマ イガッカイショウ ジュショウ ロンブン)シシツ テイカ リョウホウ ニ ヨル ケイドウミャク プラーク アンテイカ ノ ヒョウカ : チョウオンパ integrated backscatter オ モチイタ カラーマッピング システム ノ カイハツ ト リンショウ オウヨウ
- Effect of statin therapy on carotid artery plaque assessed by integrated backscatter color mapping : Development of imaging analytical software and its application on3cases
- シシツ テイカ リョウホウ ニヨル ケイドウミャク プラーク アンテイカ ノ ヒョウカ : チョウオンパ integrated backscatter オ モチイタ カラー マッピング システム ノ カイハツ ト リンショウ オウヨウ
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Background : The carotid plaque vulnerability is related to myocardial and cerebral infarction. We intended to develop an imaging system which enables to visualize tissue characteristics in the carotid plaques based on ultrasound integrated backscatter(IB). And to test its clinical efficacy, effect of the statin therapy on the plaques was evaluated with our software. Methods and Results : Carotid ultrasound examination was performed and ultrasonographic RAW data of the plaques were obtained from8patients undergoing carotid artery endarterectomy. Tissue characteristics in the plaques of resected examples were compared with preoperative ultrasonic images and the tissue IB values corresponding to the specimens were determined for developing our imaging system. Using this system, Color-coded maps of plaques in the three patients were constructed before and after lipid lowing therapy. We could demonstrate that lipid fraction in each plaque decreased and fibrous or calcification fraction increased in the follow-up study. Conclusions : Changes in histology of carotid plaques by statin could visualized with our imaging system. This technique may become a useful tool for the management of atherosclerosis.
収録刊行物
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- 四国医学雑誌
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四国医学雑誌 68 (3-4), 147-152, 2012-08-25
徳島医学会
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詳細情報 詳細情報について
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- CRID
- 1050282812711314944
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- NII論文ID
- 40019424511
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- NII書誌ID
- AN00102041
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- ISSN
- 00373699
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- NDL書誌ID
- 023965573
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- 本文言語コード
- ja
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- 資料種別
- journal article
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- データソース種別
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- IRDB
- NDL
- CiNii Articles