Green Molecular Transformation in Dual Catalysis: Photoredox Activation of Vitamin B<sub>12</sub> Using Heterogeneous Photocatalyst

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タイトル別名
  • Green Molecular Transformation in Dual Catalysis: Photoredox Activation of Vitamin B_12 Using Heterogeneous Photocatalyst

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説明

This concept focuses on dual-catalysis using metal complexes and heterogeneous photocatalysts. Vitamin B_12 derivatives are sophisticated metal complexes that facilitate enzymatic reactions in the biological systems. The B_12 enzymes inspired reactions catalytically proceed in dual-catalyst systems of B_12 derivatives and heterogeneous photocatalysts, such as titanium oxide (TiO_2) and metal-organic frameworks (MOFs), under light irradiation. The cobalt ions in vitamin B12 derivatives are effectively reduced by photoexcited photocatalysts, producing low-valent Co(I) species. The photoinduced nucleophilic Co(I) species react with an alkyl halide to form an organometallic complex with a Co-C bond. The Co-C bond dissociates during photolysis to generate alkyl radicals. Based on this mechanism, dual-catalysis effectively promotes various light-driven organic syntheses and light-driven dehalogenation reactions of toxic alkyl halides. The concepts of the dual-catalyst system and recent progress in this field are discussed in this concept.

収録刊行物

  • ChemPlusChem

    ChemPlusChem 89 (6), e202400041-, 2024-03-12

    Wiley

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詳細情報 詳細情報について

  • CRID
    1050303395628682624
  • DOI
    10.1002/cplu.202400041
  • ISSN
    21926506
  • HANDLE
    2324/7169321
  • 本文言語コード
    en
  • 資料種別
    journal article
  • データソース種別
    • IRDB
    • Crossref
    • KAKEN

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