{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360002215819481088.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/j.bbalip.2014.06.009"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S1388198114001206?httpAccept=text/plain"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S1388198114001206?httpAccept=text/xml"}},{"identifier":{"@type":"PMID","@value":"24968752"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Organization and functions of glycolipid-enriched microdomains in phagocytes"}],"description":[{"notation":[{"@value":"Populations of glycolipids change markedly during leukocyte differentiation, suggesting that these molecules are involved in biological functions. About 70% of the glycosphingolipids in human neutrophils are lactosylceramide, a molecule also expressed on monocytes and dendritic cells, but not on lymphocytes. In contrast, phosphatidylglucoside is mainly expressed on neutrophils. STED microscopic analysis showed that phosphatidylglucoside and lactosylceramide form different domains on plasma membranes of neutrophils, with phosphatidylglucoside preferentially expressed along the neutrophil differentiation pathway. Phosphatidylglucoside was found to mediate the differentiation of HL-60 cells into the neutrophilic lineage, and to be involved in FAS-dependent neutrophil apoptosis. In contrast, lactosylceramide was only expressed on mature neutrophils. Complexes of lactosylceramide and the Src family kinase Lyn form membrane microdomains. LacCer-enriched membrane microdomains mediate neutrophil innate immune responses; e.g. chemotaxis, phagocytosis, and superoxide generation. C24 fatty acid chains of LacCer are indispensable for the formation of LacCer-Lyn complexes and for LacCer-dependent functions. Moreover, Lyn-coupled LacCer-enriched microdomains serve as signal transduction platforms for αMβ2 integrin-mediated phagocytosis. This review describes the organization and potential functions of glycolipids in phagocytes, as well as the roles of both phosphatidylglucoside and lactosylceramide in neutrophils. This article is part of a Special Issue entitled Linking transcription to physiology in lipidomics."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380847868919041281","@type":"Researcher","foaf:name":[{"@value":"Roudy C. Ekyalongo"}]},{"@id":"https://cir.nii.ac.jp/crid/1420564276177449216","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70514933"},{"@type":"NRID","@value":"1000070514933"},{"@type":"NRID","@value":"9000006585971"},{"@type":"NRID","@value":"9000253169423"},{"@type":"NRID","@value":"9000257807122"},{"@type":"NRID","@value":"9000364953334"},{"@type":"NRID","@value":"9000021870356"},{"@type":"NRID","@value":"9000021999955"},{"@type":"NRID","@value":"9000254406824"},{"@type":"NRID","@value":"9000398022715"},{"@type":"NRID","@value":"9000018920606"},{"@type":"NRID","@value":"9000364952683"},{"@type":"NRID","@value":"9000408609665"},{"@type":"NRID","@value":"9000021193188"},{"@type":"NRID","@value":"9000257814114"},{"@type":"NRID","@value":"9000409378123"},{"@type":"NRID","@value":"9000021932150"},{"@type":"NRID","@value":"9000408608410"},{"@type":"NRID","@value":"9000018537664"},{"@type":"NRID","@value":"9000018183593"},{"@type":"NRID","@value":"9000364951132"},{"@type":"NRID","@value":"9000347362423"},{"@type":"NRID","@value":"9000391605333"},{"@type":"NRID","@value":"9000405616089"},{"@type":"NRID","@value":"9000257971071"},{"@type":"NRID","@value":"9000020306775"},{"@type":"NRID","@value":"9000391973152"},{"@type":"NRID","@value":"9000011148165"},{"@type":"NRID","@value":"9000408609664"},{"@type":"NRID","@value":"9000405616101"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/nhito777"}],"foaf:name":[{"@value":"Hitoshi Nakayama"}]},{"@id":"https://cir.nii.ac.jp/crid/1380847868919041280","@type":"Researcher","foaf:name":[{"@value":"Katsunari Kina"}]},{"@id":"https://cir.nii.ac.jp/crid/1380847868919041282","@type":"Researcher","foaf:name":[{"@value":"Naoko Kaga"}]},{"@id":"https://cir.nii.ac.jp/crid/1380847868919041283","@type":"Researcher","foaf:name":[{"@value":"Kazuhisa Iwabuchi"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13881981"}],"prism:publicationName":[{"@value":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2015-01","prism:volume":"1851","prism:number":"1","prism:startingPage":"90","prism:endingPage":"97"},"reviewed":"false","dc:rights":["https://www.elsevier.com/tdm/userlicense/1.0/","https://www.elsevier.com/legal/tdmrep-license"],"url":[{"@id":"https://api.elsevier.com/content/article/PII:S1388198114001206?httpAccept=text/plain"},{"@id":"https://api.elsevier.com/content/article/PII:S1388198114001206?httpAccept=text/xml"}],"createdAt":"2014-06-23","modifiedAt":"2025-10-25","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Phagocytes","dc:title":"Phagocytes"},{"@id":"https://cir.nii.ac.jp/all?q=Neutrophils","dc:title":"Neutrophils"},{"@id":"https://cir.nii.ac.jp/all?q=Lactosylceramides","dc:title":"Lactosylceramides"},{"@id":"https://cir.nii.ac.jp/all?q=Cell%20Differentiation","dc:title":"Cell Differentiation"},{"@id":"https://cir.nii.ac.jp/all?q=Glycerophospholipids","dc:title":"Glycerophospholipids"},{"@id":"https://cir.nii.ac.jp/all?q=Membrane%20Microdomains","dc:title":"Membrane Microdomains"},{"@id":"https://cir.nii.ac.jp/all?q=Antigens,%20CD","dc:title":"Antigens, CD"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Glycolipids","dc:title":"Glycolipids"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040000782259199488","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"25461011"},{"@type":"JGN","@value":"JP25461011"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25461011/"}],"notation":[{"@language":"ja","@value":"血管微小環境を介した肝類洞リモデリング制御機構の解明と肝再生治療への応用"},{"@language":"en","@value":"Mechanism of liver regeneration in regulation of sinusoidal remodeling through vascular nich"}]},{"@id":"https://cir.nii.ac.jp/crid/1040282257250727424","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"25860831"},{"@type":"JGN","@value":"JP25860831"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25860831/"}],"notation":[{"@language":"ja","@value":"貪食細胞によるスフィンゴ糖脂質を介した病原性抗酸菌の認識応答機構の解明"},{"@language":"en","@value":"The glycosphingolipid-mediated recognition of mycobacteria by human phagocytes"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011144328144000","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"SRC-dependent outside-in signalling is a key step in the process of autoregulation of beta2 integrins in polymorphonuclear cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011145318808192","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Apoptotic Pathways"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011145714702592","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Phosphoinositide-3 Kinase Survival Signaling Mechanism in Sepsis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013200105910912","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The β-Glucan-Binding Lectin Site of Mouse CR3 (CD11b/CD18) and Its Function in Generating a Primed State of the Receptor That Mediates Cytotoxic Activation in Response to iC3b-Opsonized Target Cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360283690828961920","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Pattern Recognition Receptors and Inflammation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619535771264","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"PI3K/Akt and apoptosis: size matters"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620346483328","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Innate immunity and cardiomyocytes in ischemic heart disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574093700543488","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Gangliosides from Human Melanoma Tumors Impair Dendritic Cell Differentiation from Monocytes and Induce Their Apoptosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094103629952","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Rafts defined: a report on the Keystone symposium on lipid rafts and cell function"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094905529088","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Soluble beta-glucan polysaccharide binding to the lectin site of neutrophil or natural killer cell complement receptor type 3 (CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized target cells."}]},{"@id":"https://cir.nii.ac.jp/crid/1360574096289446144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Characteristic incorporation of ganglioside GM3, which induces monocytic differentiation in human myelogenous leukemia HL-60 cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855568443915008","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"MEMBRANE DOMAINS"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855568882470528","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Novel Neutrophil Differentiation Marker Phosphatidylglucoside Mediates Neutrophil Apoptosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855568991272960","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Critical Role for Caspases 3 and 8 in Neutrophil But Not Eosinophil Apoptosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570704549376","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Dynamic and Structural Properties of Sphingolipids as Driving Forces for the Formation of Membrane Domains"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857597253552896","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A synthetic ceramide analog, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, selectively inhibits adherence during macrophage differentiation of human leukemia cells."}]},{"@id":"https://cir.nii.ac.jp/crid/1360857691187427968","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cytoplasmic tails of human complement receptor type 3 (CR3, CD11b/CD18) regulate ligand avidity and the internalization of occupied receptors."}]},{"@id":"https://cir.nii.ac.jp/crid/1360861291383401344","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Glycolipid antigens of human polymorphonuclear neutrophils and the inducible HL-60 myeloid leukemia line."}]},{"@id":"https://cir.nii.ac.jp/crid/1360861291384522496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Analysis of the sugar specificity and molecular location of the β-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861295373251328","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65)"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044106554880","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Life and death by death receptors"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044374603392","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Characteristic expression of glycosphingolipid profiles in the bipotential cell differentiation of human promyelocytic leukemia cell line HL-60"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520030529152","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A monoclonal antibody to glucosylceramide inhibits the growth of Fonsecaea pedrosoi and enhances the antifungal action of mouse macrophages"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520848610048","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Structure of Detergent-Resistant Membrane Domains: Does Phase Separation Occur in Biological Membranes?"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993775447296","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Isolation and mass spectrometry characterization of molecular species of lactosylceramides using liquid chromatography-electrospray ion trap mass spectrometry"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994132756608","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ganglioside GD1a impedes lipopolysaccharide-induced maturation of human dendritic cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994519879040","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Regulation of interleukin-8 via an airway epithelial signaling cascade"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994686899968","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Neutrophils and immunity: challenges and opportunities"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995331398144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Glucosylceramide synthase and glycosphingolipid synthesis"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995332492672","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Preferential expression of phosphatidylglucoside along neutrophil differentiation pathway"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995681264256","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The lactosylceramide binding specificity of Helicobacter pylori"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981468536289024","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Reactive oxygen species limit neutrophil life span by activating death receptor signaling"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469165091456","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"NAD glycohydrolase specifically induced by retinoic acid in human leukemic HL-60 cells. Identification of the NAD glycohydrolase as leukocyte cell surface antigen CD38"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469787941632","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Milk‐Derived GM<sub>3</sub> and GD<sub>3</sub> Differentially Inhibit Dendritic Cell Maturation and Effector Functionalities"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981471111889536","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Redox Regulation of Neutrophil Apoptosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262943555000704","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"How to Get from Here to There: Macrophage Recruitment in Alzheimers Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944278615424","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Danger Model: A Renewed Sense of Self"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262945295340800","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Subcellular localization of glycosphingolipids in human neutrophils"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544418399318912","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Phosphatidylglucoside Forms Specific Lipid Domains on the Outer Leaflet of the Plasma Membrane"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544420952134144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"DETECTING MICRODOMAINS IN INTACT CELL MEMBRANES"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825894239262336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Human Myelogenous Leukemia Cell Line HL-60 Cells Resistant to Differentiation Induction by Retinoic Acid"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895545085184","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Integrin cytoplasmic interactions and bidirectional transmembrane signalling"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895778110208","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Glycosphingolipid Binding Specificities of Neisseria meningitidis and Haemophilus influenzae: Detection, Isolation, and Characterization of a Binding-Active Glycosphingolipid from Human Oropharyngeal Epithelium"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369341600512","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ganglioside GM1 and asialo-GM1 at low concentration are preferentially incorporated into the gel phase in two-component, two-phase phosphatidylcholine bilayers"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107370499133056","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Carbohydrate-dependent signaling from the phosphatidylglucoside-based  microdomain induces granulocytic differentiation of HL60 cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107370786667392","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Lactosylceramide-enriched glycosphingolipid signaling domain mediates superoxide generation from human neutrophils"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388843573295104","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Lactosylceramide: Effect of Acyl Chain Structure on Phase Behavior and Molecular Packing"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388843877520128","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844918506240","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Involvement of very long fatty acid-containing lactosylceramide in lactosylceramide-mediated superoxide generation and migration in neutrophils"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845092157952","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Bacterial endotoxin: molecular relationships of structure to activity and function"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845482228352","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Total metabolic flow of glycosphingolipid biosynthesis is regulated by UDP-GlcNAc:lactosylceramide beta 1–>3N-acetylglucosaminyltransferase and CMP-NeuAc:lactosylceramide alpha 2–>3 sialyltransferase in human hematopoietic cell line HL-60 during differentiation."}]},{"@id":"https://cir.nii.ac.jp/crid/1363670318605239552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Glycosphingolipids in Cellular Interaction, Differentiation, and Oncogenesis"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670318946005504","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Induction of human neutrophil chemotaxis by <i>Candida albicans</i>-derived β-1,6-long glycoside side-chain-branched β-glucan"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670320012960256","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ganglioside GM3: an acidic membrane component that increases during macrophage-like cell differentiation can induce monocytic differentiation of human myeloid and monocytoid leukemic cell lines HL-60 and U937."}]},{"@id":"https://cir.nii.ac.jp/crid/1363670320073446784","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"New insights in glycosphingolipid function: \"glycosignaling domain,\" a cell surface assembly of glycosphingolipids with signal transducer molecules, involved in cell adhesion coupled with signaling"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670320970377728","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670321144763264","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Expression of leukocyte differentiation antigens during the differentiation of HL-60 cells induced by 1,25-dihydroxyvitamin D3: comparison with the maturation of normal monocytic and granulocytic bone marrow cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670321257606272","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Structure, organization, and function of glycosphingolipids in membrane"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951793497720576","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Expression of cell surface antigens during the differentiation of HL-60 cells induced by 1,25-ihydroxyvitamin D3, retinoic acid and DMSO"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951794303170432","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Regulation of Inflammatory Monocyte/Macrophage Recruitment from the Bone Marrow during Murine Cytomegalovirus Infection: Role for Type I Interferons in Localized Induction of CCR2 Ligands"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951796188512128","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Host-Viral Interactions: Role of Pattern Recognition Receptors (PRRs) in Human Pneumovirus Infections"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233268770152064","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Galectins in innate immunity: dual functions of host soluble β‐galactoside‐binding lectins as damage‐associated molecular patterns (DAMPs) and as receptors for pathogen‐associated molecular patterns (PAMPs)"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269086234496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Phosphatidylglucoside Exists as a Single Molecular Species with Saturated Fatty Acyl Chains in Developing Astroglial Membranes"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269895536384","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Expression of cellular homologues of retroviral onc genes in human hematopoietic cells."}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270731420288","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"ANIMAL GLYCOSPHINGOLIPIDS AS MEMBRANE ATTACHMENT SITES FOR BACTERIA"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233271161923200","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Localization of globoside and forssman glycolipids on erythrocyte membranes"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233271272391552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Early events in spontaneous neutrophil apoptosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1371975841500039818","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Pathogens: raft hijackers"}]},{"@id":"https://cir.nii.ac.jp/crid/1371975841500040323","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Quantitative analysis of LacCer/CDw17 in human myelogenous leukaemic cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1390845712997889792","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"ヒト好中球に特異的なラクトシルセラミドを介した感染免疫応答機構"},{"@language":"en","@value":"Lactosylceramide-enriched Lipid Raft-mediated Infection Immunity"},{"@language":"ja-Kana","@value":"ヒト コウチュウキュウ ニ トクイテキ ナ ラクトシルセラミド オ カイシタ カンセン メンエキ オウトウ キコウ"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1016/j.bbalip.2014.06.009"},{"@type":"KAKEN","@value":"PRODUCT-20218690"},{"@type":"KAKEN","@value":"PRODUCT-15166472"},{"@type":"OPENAIRE","@value":"doi_dedup___::a340b3488aa9429be7b39196e6067173"},{"@type":"CROSSREF","@value":"10.3314/mmj.18.008_references_DOI_61gQT0tWSYxtreEngmQIETvCydM"}]}