{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360004232147539584.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/j.febslet.2014.04.047"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2Fj.febslet.2014.04.047"}},{"identifier":{"@type":"URI","@value":"https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/j.febslet.2014.04.047"}},{"identifier":{"@type":"PMID","@value":"24815688"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Does a shift to limited glucose activate checkpoint control in fission yeast?"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Here we review cell cycle control in the fission yeast, <jats:italic>Schizosaccharomyces pombe,</jats:italic> in response to an abrupt reduction of glucose concentration in culture media. <jats:italic>S. pombe</jats:italic> arrests cell cycle progression when transferred from media containing 2.0% glucose to media containing 0.1%. After a delay, <jats:italic>S. pombe</jats:italic> resumes cell division at a surprisingly fast rate, comparable to that observed in 2% glucose. We found that a number of genes, including zinc‐finger transcription factor Scr1, CaMKK‐like protein kinase Ssp1, and glucose transporter Ght5, enable rapid cell division in low glucose. In this article, we examine whether cell cycle checkpoint‐like control operates during the delay and after resumption of cell division in limited‐glucose. Using microarray analysis and genetic screening, we identified several candidate genes that may be involved in controlling this low‐glucose adaptation.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420845751138374912","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"30352123"},{"@type":"NRID","@value":"1000030352123"},{"@type":"NRID","@value":"9000009713258"},{"@type":"NRID","@value":"9000006092922"},{"@type":"NRID","@value":"9000412300506"},{"@type":"NRID","@value":"9000403041570"},{"@type":"NRID","@value":"9000404510507"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/shigeaki_saitoh"}],"foaf:name":[{"@value":"Shigeaki Saitoh"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004232147539328","@type":"Researcher","foaf:name":[{"@value":"Mitsuhiro Yanagida"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00145793"},{"@type":"EISSN","@value":"18733468"}],"prism:publicationName":[{"@value":"FEBS Letters"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2014-05-08","prism:volume":"588","prism:number":"15","prism:startingPage":"2373","prism:endingPage":"2378"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","dc:rights":["http://creativecommons.org/licenses/by-nc-nd/4.0/"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2Fj.febslet.2014.04.047"},{"@id":"https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/j.febslet.2014.04.047"}],"createdAt":"2014-05-08","modifiedAt":"2023-09-18","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Transcription,%20Genetic","dc:title":"Transcription, Genetic"},{"@id":"https://cir.nii.ac.jp/all?q=Glucose%20uptake","dc:title":"Glucose uptake"},{"@id":"https://cir.nii.ac.jp/all?q=Glucose%20Transport%20Proteins,%20Facilitative","dc:title":"Glucose Transport Proteins, Facilitative"},{"@id":"https://cir.nii.ac.jp/all?q=Starvation%20response","dc:title":"Starvation response"},{"@id":"https://cir.nii.ac.jp/all?q=Cell%20Cycle%20Checkpoints","dc:title":"Cell Cycle Checkpoints"},{"@id":"https://cir.nii.ac.jp/all?q=Cell%20cycle","dc:title":"Cell cycle"},{"@id":"https://cir.nii.ac.jp/all?q=Glucose","dc:title":"Glucose"},{"@id":"https://cir.nii.ac.jp/all?q=Schizosaccharomyces%20pombe","dc:title":"Schizosaccharomyces pombe"},{"@id":"https://cir.nii.ac.jp/all?q=Gene%20Expression%20Regulation,%20Fungal","dc:title":"Gene Expression Regulation, Fungal"},{"@id":"https://cir.nii.ac.jp/all?q=Hexose%20transporter","dc:title":"Hexose transporter"},{"@id":"https://cir.nii.ac.jp/all?q=Schizosaccharomyces","dc:title":"Schizosaccharomyces"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040282257187470976","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"24570221"},{"@type":"JGN","@value":"JP24570221"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24570221/"}],"notation":[{"@language":"ja","@value":"環境グルコース濃度に応じたトランスポーター分子の機能発現制御メカニズムの解明"},{"@language":"en","@value":"Regulation of the expression and the function of glucose transporters in response to the enviromental glucose concentrations."}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050863241237054976","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"In fission yeast, 65 non-essential mitochondrial proteins related to respiration and stress become essential in low-glucose 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