{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360004232350914432.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/j.lungcan.2014.11.010"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0169500214004838?httpAccept=text/xml"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0169500214004838?httpAccept=text/plain"}},{"identifier":{"@type":"PMID","@value":"25481488"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Close association of IASLC/ATS/ERS lung adenocarcinoma subtypes with glucose-uptake in positron emission tomography"}],"description":[{"notation":[{"@value":"Correlations between maximum standardized uptake value (SUVmax) in fluorodeoxyglucose positron emission tomography (FDG-PET) and IASLC/ATS/ERS histopathologic subtypes of lung adenocarcinoma remain unclear. Therefore, the aim of this study was to retrospectively clarify associations between SUVmax and adenocarcinoma subtypes with postoperative outcomes.Associations of SUVmax measured in preoperative FDG-PET/CT and histologic subtypes of lung adenocarcinoma resected in our hospital were analyzed retrospectively. Overall and disease-free survival rates after surgery were calculated by the Kaplan-Meier method, and survival differences between patient groups were tested by the log-rank test. Multivariate analysis for survival was performed using the Cox regression model.A total of 255 patients (130 men and 125 women; mean age, 69 years; range, 22-88 years) were included in the study. Clinical stages included IA in 151 patients, IB in 79, IIA in 9, IIB in 10, and IIIA in 6. SUVmax was closely associated with histologic subtype in resected specimens (p0.0001). Values were highest in micropapillary predominant invasive adenocarcinoma (MPA) followed by solid predominant (SPA), invasive mucinous (IMA), acinar predominant (APA), papillary predominant (PPA), lepidic predominant (LPA), minimally invasive adenocarcinoma (MIA), and adenocarcinoma in situ (AIS). When the subtypes were classified into three subgroups [group A, AIS+MIA+LPA (low risk); group B, APA+PPA+IMA (intermediate risk); and group C, SPA+MPP (high risk)] by expected postoperative prognoses, there were significant differences in SUVmax among the subgroups corresponding to recurrence risk (p=0.0001).Preoperative SUVmax was closely associated with both adenocarcinoma subtype and aggregated subgroups, reflecting malignant grade of the tumor and prognosis."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380004232350914433","@type":"Researcher","foaf:name":[{"@value":"Haruhiko Nakamura"}]},{"@id":"https://cir.nii.ac.jp/crid/1420282801188386944","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"60420965"},{"@type":"NRID","@value":"1000060420965"},{"@type":"NRID","@value":"9000243899789"},{"@type":"NRID","@value":"9000018796000"},{"@type":"NRID","@value":"9000253396248"},{"@type":"NRID","@value":"9000397866013"},{"@type":"NRID","@value":"9000397972543"},{"@type":"NRID","@value":"9000399803794"},{"@type":"NRID","@value":"9000356667215"},{"@type":"NRID","@value":"9000010346020"},{"@type":"NRID","@value":"9000398144008"},{"@type":"NRID","@value":"9000363909644"},{"@type":"NRID","@value":"9000261045820"},{"@type":"NRID","@value":"9000006491537"},{"@type":"NRID","@value":"9000261643113"},{"@type":"NRID","@value":"9000257919665"},{"@type":"NRID","@value":"9000378081135"},{"@type":"NRID","@value":"9000022061611"},{"@type":"NRID","@value":"9000402599994"},{"@type":"NRID","@value":"9000347090932"},{"@type":"NRID","@value":"9000399374161"},{"@type":"NRID","@value":"9000257918373"},{"@type":"NRID","@value":"9000018258430"},{"@type":"NRID","@value":"9000311506539"},{"@type":"NRID","@value":"9000004678332"},{"@type":"NRID","@value":"9000020307249"},{"@type":"NRID","@value":"9000399785489"},{"@type":"NRID","@value":"9000301717174"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/saji-q"}],"foaf:name":[{"@value":"Hisashi Saji"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004232350914437","@type":"Researcher","foaf:name":[{"@value":"Takuo Shinmyo"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004232350914438","@type":"Researcher","foaf:name":[{"@value":"Rie Tagaya"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004232350914436","@type":"Researcher","foaf:name":[{"@value":"Noriaki Kurimoto"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004232350914432","@type":"Researcher","foaf:name":[{"@value":"Hirotaka Koizumi"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004232350914435","@type":"Researcher","foaf:name":[{"@value":"Masayuki Takagi"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"01695002"}],"prism:publicationName":[{"@value":"Lung Cancer"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2015-01","prism:volume":"87","prism:number":"1","prism:startingPage":"28","prism:endingPage":"33"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","dc:rights":["https://www.elsevier.com/tdm/userlicense/1.0/"],"url":[{"@id":"https://api.elsevier.com/content/article/PII:S0169500214004838?httpAccept=text/xml"},{"@id":"https://api.elsevier.com/content/article/PII:S0169500214004838?httpAccept=text/plain"}],"createdAt":"2014-11-29","modifiedAt":"2019-08-17","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Adult","dc:title":"Adult"},{"@id":"https://cir.nii.ac.jp/all?q=Aged,%2080%20and%20over","dc:title":"Aged, 80 and over"},{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Lung%20Neoplasms","dc:title":"Lung Neoplasms"},{"@id":"https://cir.nii.ac.jp/all?q=Adenocarcinoma%20of%20Lung","dc:title":"Adenocarcinoma of Lung"},{"@id":"https://cir.nii.ac.jp/all?q=Adenocarcinoma","dc:title":"Adenocarcinoma"},{"@id":"https://cir.nii.ac.jp/all?q=Middle%20Aged","dc:title":"Middle Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Tumor%20Burden","dc:title":"Tumor Burden"},{"@id":"https://cir.nii.ac.jp/all?q=Young%20Adult","dc:title":"Young Adult"},{"@id":"https://cir.nii.ac.jp/all?q=Fluorodeoxyglucose%20F18","dc:title":"Fluorodeoxyglucose F18"},{"@id":"https://cir.nii.ac.jp/all?q=Risk%20Factors","dc:title":"Risk Factors"},{"@id":"https://cir.nii.ac.jp/all?q=Positron-Emission%20Tomography","dc:title":"Positron-Emission Tomography"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Tomography,%20X-Ray%20Computed","dc:title":"Tomography, X-Ray Computed"},{"@id":"https://cir.nii.ac.jp/all?q=Aged","dc:title":"Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Neoplasm%20Staging","dc:title":"Neoplasm Staging"},{"@id":"https://cir.nii.ac.jp/all?q=Retrospective%20Studies","dc:title":"Retrospective Studies"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040000782215214080","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"24592104"},{"@type":"JGN","@value":"JP24592104"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24592104/"}],"notation":[{"@language":"ja","@value":"多次元医用画像と深部情報可視化映像によるリアルタイム手術支援システムの開発"},{"@language":"en","@value":"Development of real-time surgical assisted systems using multi-dimensional medical image and optical technique of deep visualization"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360002221241971328","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Diagnosis of Lung Cancer in Small Biopsies and Cytology: Implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017282220005120","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Distinct Prognostic Impact of PET Findings Based on Radiological Appearance in Clinical Stage IA Lung Adenocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565171195392768","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Diagnosis of Lung Adenocarcinoma in Resected Specimens: Implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094741006336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"FDG-PET SUVmax Combined with IASLC/ATS/ERS Histologic Classification Improves the Prognostic Stratification of Patients with Stage I Lung Adenocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095428518912","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The variation of prognostic significance of Maximum Standardized Uptake Value of [18F]-fluoro-2-deoxy-glucose positron emission tomography in different histological subtypes and pathological stages of surgically resected Non-Small Cell Lung Carcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095842109056","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Prognostic value of the IASLC/ATS/ERS classification in stage I lung adenocarcinoma patients—Based on a hospital study in China"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846644509144960","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society: International Multidisciplinary Classification of Lung Adenocarcinoma: Executive Summary"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569218871808","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Primary Tumor Standardized Uptake Value (SUVmax) Measured on Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) is of Prognostic Value for Survival in Non-small Cell Lung Cancer (NSCLC): A Systematic Review and Meta-Analysis (MA) by the European Lung Cancer Working Party for the IASLC Lung Cancer Staging Project"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569795834624","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Does Lung Adenocarcinoma Subtype Predict Patient Survival?: A Clinicopathologic Study Based on the New International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Lung Adenocarcinoma Classification"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570052919552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The utility of the proposed IASLC/ATS/ERS lung adenocarcinoma subtypes for disease prognosis and correlation of driver gene alterations"}]},{"@id":"https://cir.nii.ac.jp/crid/1360865816809200000","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Stepwise progression of invasive mucinous adenocarcinoma based on radiological and biological characteristics"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045019434496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Impact of Micropapillary Histologic Subtype in Selecting Limited Resection vs Lobectomy for Lung Adenocarcinoma of 2cm or Smaller"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045955689728","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Prognostic Importance of the Standardized Uptake Value on <sup>18</sup>F-Fluoro-2-Deoxy-Glucose–Positron Emission Tomography Scan in Non–Small-Cell Lung Cancer: An Analysis of 125 Cases"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418519507100032","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Whole-body 18F-fluorodeoxyglucose positron emission tomography in preoperative evaluation of lung cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993581418624","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Novel Histologic International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification System of Lung Adenocarcinoma Is a Stage-Independent Predictor of Survival"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944849762304","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Biological correlates of FDG uptake in non-small cell lung cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544421282930304","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Prognostic significance of the IASLC/ATS/ERS classification in Chinese patients—A single institution retrospective study of 292 lung adenocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895570728832","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Prognostic significance of [<sup>18</sup>F]fluorodeoxyglucose uptake on positron emission tomography in patients with pathologic stage I lung adenocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107370621269248","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Preoperative F-18 Fluorodeoxyglucose-Positron Emission Tomography Maximal Standardized Uptake Value Predicts Survival After Lung Cancer Resection"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844910054144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Epidermal Growth Factor Receptor Mutation in Lung Adenocarcinomas: Relationship with CT Characteristics and Histologic Subtypes"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845145190144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Micropapillary and solid subtypes of invasive lung adenocarcinoma: Clinical predictors of histopathology and outcome"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951793278738048","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Impact of proposed IASLC/ATS/ERS classification of lung adenocarcinoma: prognostic subgroups and implications for further revision of staging based on analysis of 514 stage I cases"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951795653482112","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"New Pathologic Classification of Lung Cancer: Relevance for Clinical Practice and Clinical Trials"}]},{"@id":"https://cir.nii.ac.jp/crid/1371412891987384071","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Positron emission tomography for predicting recurrence in stage I lung adenocarcinoma: standardized uptake value corrected by mean liver standardized uptake value"}]},{"@id":"https://cir.nii.ac.jp/crid/1390574732433984256","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Predicting Malignancy Grade of Lung Adenocarcinoma by Preoperative Diagnostic Imaging"},{"@language":"ja","@value":"高分解能CTとFDG-PET/CTによる肺腺癌の悪性度予測"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1016/j.lungcan.2014.11.010"},{"@type":"KAKEN","@value":"PRODUCT-14715314"},{"@type":"OPENAIRE","@value":"doi_dedup___::e1c8ae81d8ad050cf4dbdc9b1be67c89"},{"@type":"CROSSREF","@value":"10.1016/j.cllc.2022.10.007_references_DOI_NeVjg4ZMFE0HYr5vHM6HFNS4uYg"},{"@type":"CROSSREF","@value":"10.2482/haigan.62.299_references_DOI_NeVjg4ZMFE0HYr5vHM6HFNS4uYg"},{"@type":"CROSSREF","@value":"10.1016/j.lungcan.2023.107348_references_DOI_NeVjg4ZMFE0HYr5vHM6HFNS4uYg"}]}