{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360004236339201920.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1155/2011/171034"}},{"identifier":{"@type":"URI","@value":"http://downloads.hindawi.com/archive/2011/171034.pdf"}},{"identifier":{"@type":"URI","@value":"http://downloads.hindawi.com/archive/2011/171034.xml"}},{"identifier":{"@type":"PMID","@value":"21760819"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"The Effects of Ghrelin on Energy Balance and Psychomotor Activity in a Goldfish Model: An Overview"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>The goldfish (<jats:italic>Carassius auratus</jats:italic>) has a number of merits as a laboratory animal, and we have extensively identified the mechanisms by which ghrelin regulates food intake in this species. For the first time, we have purified and characterized 11 molecular variants of ghrelin that are present in goldfish intestine and shown that 17-residue ghrelin, the predominant form with<jats:italic>n</jats:italic>-octanoyl modification, is biologically active and implicated in the regulation of food intake as an endogenous orexigenic factor. Ghrelin and its receptor system are present not only in peripheral tissues such as stomach and intestine, but also in the central nervous system. Recent studies have also revealed that a number of neuropeptides are widely distributed in the brain in key areas of emotional regulation, and their role as modulators of behavioral states is being increasingly recognized. Interestingly, administration of ghrelin induces an orexigenic effect and also modifies locomotor activity, suggesting the involvement of ghrelin in feeding control and regulation of energy balance. Information derived from studies of ghrelin has been increasing, and important results have been obtained from both fish and mammals. Here, we present an overview of the effects of ghrelin on energy balance and psychomotor activity in the goldfish as an animal model. The available data provide an insight into evolutionary background of ghrelin's multiple actions on energy homeostasis in vertebrates.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380004236339202048","@type":"Researcher","foaf:name":[{"@value":"Ki Sung Kang"}],"jpcoar:affiliationName":[{"@value":"Laboratory of Regulatory Biology, Graduate School of Science and Engineering, University of Toyama, 3190-Gofuku, Toyama 930-8555, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004236339202176","@type":"Researcher","foaf:name":[{"@value":"Satowa Yahashi"}],"jpcoar:affiliationName":[{"@value":"Laboratory of Regulatory Biology, Graduate School of Science and Engineering, University of Toyama, 3190-Gofuku, Toyama 930-8555, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1420845751152576256","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"60222303"},{"@type":"NRID","@value":"1000060222303"},{"@type":"NRID","@value":"9000308727159"},{"@type":"NRID","@value":"9000313624875"},{"@type":"NRID","@value":"9000258075759"},{"@type":"NRID","@value":"9000364747084"},{"@type":"NRID","@value":"9000018229057"},{"@type":"NRID","@value":"9000283623069"},{"@type":"NRID","@value":"9000020854166"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/readMT-07CBR250R"}],"foaf:name":[{"@value":"Kouhei Matsuda"}],"jpcoar:affiliationName":[{"@value":"Laboratory of Regulatory Biology, Graduate School of Science and Engineering, University of Toyama, 3190-Gofuku, Toyama 930-8555, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"16879767"},{"@type":"EISSN","@value":"16879775"}],"prism:publicationName":[{"@value":"International Journal of Peptides"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2011-05-24","prism:volume":"2011","prism:startingPage":"1","prism:endingPage":"9"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","dc:rights":["http://creativecommons.org/licenses/by/3.0/"],"url":[{"@id":"http://downloads.hindawi.com/archive/2011/171034.pdf"},{"@id":"http://downloads.hindawi.com/archive/2011/171034.xml"}],"createdAt":"2011-05-24","modifiedAt":"2025-03-05","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Review%20Article","dc:title":"Review Article"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040000782071914752","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"21370025"},{"@type":"JGN","@value":"JP21370025"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21370025/"}],"notation":[{"@language":"ja","@value":"脳ペプチドによる摂食行動の脳制御機構とその進化プロセスの解明"},{"@language":"en","@value":"Neuroendocrine control of feeding behavior by neuropeptides in fish and its evolutionary modeling"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011145221402112","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Remote Sensing of Fire Severity: Assessing the Performance of the Normalized Burn Ratio"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011145566898816","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The goldfish (Carassius auratus) as a model for neuroendocrine signaling"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292618967542528","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin gene in cichlid fish is modulated by sex and development"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292618999363968","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin: a new peptide regulating the neurohormonal system, energy homeostasis and glucose metabolism"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619094131584","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Central Administration of Ghrelin and Agouti-Related Protein (83–132) Increases Food Intake and Decreases Spontaneous Locomotor Activity in Rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619365588736","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Regulation of food intake in the goldfish by interaction between ghrelin and orexin"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619556788096","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Differential monoaminergic, neuroendocrine and behavioural responses after central administration of corticotropin‐releasing factor receptor type 1 and type 2 agonists"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620357905920","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Recent Advances in the Regulation of Feeding Behavior by Neuropeptides in Fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620942263808","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin's Roles in Stress, Mood, and Anxiety Regulation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292621065290240","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Tissue Distribution of the mRNA of Ghrelin and Subtypes of Its Receptor, GHS-R, in Humans"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567182379443968","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Stimulatory effect of ghrelin on food intake in bullfrog larvae"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574093568290304","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094020227584","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Feeding Behavior of Fish and Its Control"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094087306112","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Purification and properties of ghrelin from the intestine of the goldfish, Carassius auratus"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094106659456","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Implication of neuropeptide-Y Y2 receptors in the effects of immune stress on emotional, locomotor and social behavior of mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094652080384","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The octadecaneuropeptide exerts an anxiogenic-like action in goldfish"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095251613312","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The role of gastrointestinal vagal afferents in the control of food intake: current prospects"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095294581760","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The octadecaneuropeptide [diazepam-binding inhibitor (33–50)] exerts potent anorexigenic effects in rodents"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574096531414144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system11Published on the World Wide Web on 27 June 2000."}]},{"@id":"https://cir.nii.ac.jp/crid/1360845538921188352","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Role of Nonexercise Activity Thermogenesis in Resistance to Fat Gain in Humans"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846640672060032","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Orexin System in Teleost Fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569007625216","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Behavioral effects of neuropeptides in rodent models of depression and anxiety"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570602310656","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Hypothalamic Orexin Neurons Regulate Arousal According to Energy Balance in Mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570824615552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Brain neuropeptide Y and corticotropin-releasing hormone in mediating stress and anxiety"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570960451584","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Regulation of food intake by acyl and des-acyl ghrelins in the goldfish"}]},{"@id":"https://cir.nii.ac.jp/crid/1360866223603861888","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: From Structure to Functions"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137043538433664","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Biochemical and behavioral effects of carbofuran in goldfish (<i>Carassius auratus</i>)"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137043739742080","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The CAMplexities of Central Ghrelin"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044477264512","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Neural Representation of Object Approach in a Decision-Making Motor Circuit"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045185589120","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin: a gastric peptide that regulates food intake and energy homeostasis"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045936803584","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Vulnerability to nicotine abstinence-related social anxiety-like behavior: Molecular correlates in neuropeptide Y, Y2 receptor and corticotropin releasing factor"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137046261014144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Peptide Purification, Complementary Deoxyribonucleic Acid (DNA) and Genomic DNA Cloning, and Functional Characterization of Ghrelin in Rainbow Trout"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520529652608","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cannabinoids and Ghrelin Have Both Central and Peripheral Metabolic and Cardiac Effects via AMP-activated Protein Kinase"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520565684864","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Stimulation of vagal afferents inhibits locomotion in mesencephalic cats"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520812646912","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The melanocortins and melanin-concentrating hormone in the central regulation of feeding behavior and energy homeostasis"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418521371832192","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Locomotor response to l-DOPA in reserpine-treated rats following central inhibition of aromatic l-amino acid decarboxylase: Further evidence for non-dopaminergic actions of l-DOPA and its metabolites"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418521439341056","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin: A multifunctional hormone in non-mammalian vertebrates"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995351204480","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Role of leptin in the control of feeding of goldfish Carassius auratus: interactions with cholecystokinin, neuropeptide Y and orexin A, and modulation by fasting"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995404988160","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Gut Hormones and Appetite Control"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995464894336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Purification, cDNA cloning, and characterization of ghrelin in channel catfish, Ictalurus punctatus"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995862793216","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"New Insights in Ghrelin Orexigenic Effect"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699996025409024","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A Novel Hematopoietic Granulin Induces Proliferation of Goldfish (Carassius auratus L.) Macrophages"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699996151367040","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin-Induced Food Intake Is Mediated via the Orexin Pathway"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981468770305536","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469341115392","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Kidney produces a novel acylated peptide, ghrelin"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469857226752","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Scototaxis as anxiety-like behavior in fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981471403713792","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Neuropeptides and the control of food intake in fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981471442370304","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Animal models of anxiety in mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262943356048512","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262943450991488","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Genetic approaches to studying energy balance: perception and integration"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262943545695872","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"α-Melanocyte-stimulating hormone mediates melanin-concentrating hormone-induced anorexigenic action in goldfish"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262943818035712","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin is a growth-hormone-releasing acylated peptide from stomach"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262943880431616","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Role of brain neuroactive steroids in the functional interplay between the GABAA and the NPY-Y1 receptor mediated signals in the amygdala"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262945322616192","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Roles of orexin/hypocretin in regulation of sleep/wakefulness and energy homeostasis"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544418600854016","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"PRECLINICAL STUDY: Systemic administration of ghrelin induces conditioned place preference and stimulates accumbal dopamine"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544420730374784","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544421365575296","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Stimulatory effect of n-octanoylated ghrelin on locomotor activity in the goldfish, Carassius auratus"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825894160570752","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Structural Divergence of Human Ghrelin"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825894943857024","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Differential Expression of Corticotropin-Releasing Factor (CRF) and Urotensin I Precursor Genes, and Evidence of CRF Gene Expression Regulated by Cortisol in Goldfish Brain"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895604898944","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895977922048","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"In vitro and in vivo effects of ghrelin on luteinizing hormone and growth hormone release in goldfish"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825896007527808","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Involvement of α-MSH in the social isolation induced anxiety- and depression-like behaviors in rat"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107368334971264","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Central and peripheral effects of ghrelin on energy balance, food intake and lipid metabolism in teleost fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369026276992","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Role of corticotropin-releasing factor (CRF) as a food intake regulator in goldfish"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369403616128","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Acute psychological stress raises plasma ghrelin in the rat"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107370516858368","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Pituitary adenylate cyclase activating polypeptide (PACAP) reduces food intake in mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107370731001472","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Behavioral effects of 26RFamide and related peptides"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388843669857792","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Cortical Motor System"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388843889272960","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin Is Present in Pancreatic α-Cells of Humans and Rats and Stimulates Insulin Secretion"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844080606720","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Increased novelty-induced motor activity and reduced depression-like behavior in neuropeptide Y (NPY)–Y4 receptor knockout mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845764957312","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Neuropeptide Y mediates ghrelin-induced feeding in the goldfish, Carassius auratus"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388846012192000","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A BAC library for the goldfish <i>Carassius auratus auratus</i> (Cyprinidae, Cypriniformes)"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670319198885504","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A Role of Ghrelin in Neuroendocrine and Behavioral Responses to Stress in Mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670320277524480","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951794404846336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Behavioral effect of neuropeptides related to feeding regulation in fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951794553787520","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Goldfish Ghrelin: Molecular Characterization of the Complementary Deoxyribonucleic Acid, Partial Gene Structure and Evidence for Its Stimulatory Role in Food Intake"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951794798505600","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Pharmacological Characterization of the Receptor Mediating the Anorexigenic Action of the Octadecaneuropeptide: Evidence for an Endozepinergic Tone Regulating Food Intake"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951795476288768","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"On the<i>in Vitro</i>and<i>in Vivo</i>Activity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233268390274304","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Anxiolytic-like effect of Chlorpheniramine in inhibitory avoidance in goldfish submitted to telencephalic ablation"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269030571776","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The hypothalamic–pituitary–interrenal axis and the control of food intake in teleost fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269252744960","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"CRH Signaling"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269834199168","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Amidated fish ghrelin: purification, cDNA cloning in the Japanese eel and its biological activity"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270240130432","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Identification of receptors for neuromedin U and its role in feeding"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270447206912","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ghrelin Induces Abdominal Obesity Via GHS-R-Dependent Lipid Retention"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270630918144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233271286975616","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Neuropeptide Y-Y2 receptor knockout mice: influence of genetic background on anxiety-related behaviors"}]},{"@id":"https://cir.nii.ac.jp/crid/1524232505421204992","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Rat ghrelin stimulates growth hormone and prolactin release in the tilapia, Oreochromis mossambicus"},{"@language":"ja-Kana","@value":"Rat ghrelin stimulates growth hormone and prolactin release in the tilapia Oreochromis mossambicus"},{"@language":"en","@value":"Rat Ghrelin Stimulates Growth Hormone and Prolactin Release in the Tilapia, Oreochromis mossambicus(Endocrinology) :"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1155/2011/171034"},{"@type":"KAKEN","@value":"PRODUCT-12691134"},{"@type":"KAKEN","@value":"PRODUCT-12691359"},{"@type":"OPENAIRE","@value":"doi_dedup___::93e5252c71e5fde9369b9d6ecb04bf87"},{"@type":"CROSSREF","@value":"10.1016/j.peptides.2013.10.028_references_DOI_L368nJhxS6dOTOvUEN0LBZ17Ipz"},{"@type":"CROSSREF","@value":"10.1016/b978-0-12-394623-2.00018-4_references_DOI_L368nJhxS6dOTOvUEN0LBZ17Ipz"}]}