{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360004239451589888.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3389/fnhum.2016.00368"}},{"identifier":{"@type":"PMID","@value":"27499737"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Short-Term Plasticity in a Monosynaptic Reflex Pathway to Forearm Muscles after Continuous Robot-Assisted Passive Stepping"}],"description":[{"notation":[{"@value":"Both active and passive rhythmic limb movements reduce the amplitude of spinal cord Hoffmann (H-) reflexes in muscles of moving and distant limbs. This could have clinical utility in remote modulation of the pathologically hyperactive reflexes found in spasticity after stroke or spinal cord injury. However, such clinical translation is currently hampered by a lack of critical information regarding the minimum or effective duration of passive movement needed for modulating spinal cord excitability. We therefore investigated the H-reflex modulation in the flexor carpi radialis (FCR) muscle during and after various durations (5, 10, 15, and 30 min) of passive stepping in 11 neurologically normal subjects. Passive stepping was performed by a robotic gait trainer system (Lokomat(®)) while a single pulse of electrical stimulation to the median nerve elicited H-reflexes in the FCR. The amplitude of the FCR H-reflex was significantly suppressed during passive stepping. Although 30 min of passive stepping was sufficient to elicit a persistent H-reflex suppression that lasted up to 15 min, 5 min of passive stepping was not. The duration of H-reflex suppression correlated with that of the stepping. These findings suggest that the accumulation of stepping-related afferent feedback from the leg plays a role in generating short-term interlimb plasticity in the circuitry of the FCR H-reflex."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420564276187362048","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"60435691"},{"@type":"NRID","@value":"1000060435691"},{"@type":"NRID","@value":"9000258742572"},{"@type":"NRID","@value":"9000006497152"},{"@type":"NRID","@value":"9000258742457"},{"@type":"NRID","@value":"9000003208534"},{"@type":"NRID","@value":"9000363381755"},{"@type":"NRID","@value":"9000292188227"},{"@type":"NRID","@value":"9000258742827"},{"@type":"NRID","@value":"9000283506439"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/tsunakaj"}],"foaf:name":[{"@value":"Tsuyoshi Nakajima"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004239451590150","@type":"Researcher","foaf:name":[{"@value":"Kiyotaka Kamibayashi"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004239451590148","@type":"Researcher","foaf:name":[{"@value":"Taku Kitamura"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004239451590021","@type":"Researcher","foaf:name":[{"@value":"Tomoyoshi Komiyama"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004239451589769","@type":"Researcher","foaf:name":[{"@value":"E. Paul Zehr"}]},{"@id":"https://cir.nii.ac.jp/crid/1380004239451589770","@type":"Researcher","foaf:name":[{"@value":"Kimitaka Nakazawa"}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"16625161"}],"prism:publicationName":[{"@value":"Frontiers in Human Neuroscience"}],"dc:publisher":[{"@value":"Frontiers Media SA"}],"prism:publicationDate":"2016-07-22","prism:volume":"10","prism:startingPage":"368"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","createdAt":"2016-07-21","modifiedAt":"2019-09-11","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Behavioral%20Neuroscience","dc:title":"Behavioral Neuroscience"},{"@id":"https://cir.nii.ac.jp/all?q=Biological%20Psychiatry","dc:title":"Biological Psychiatry"},{"@id":"https://cir.nii.ac.jp/all?q=Psychiatry%20and%20Mental%20health","dc:title":"Psychiatry and Mental health"},{"@id":"https://cir.nii.ac.jp/all?q=Neurology","dc:title":"Neurology"},{"@id":"https://cir.nii.ac.jp/all?q=Neuropsychology%20and%20Physiological%20Psychology","dc:title":"Neuropsychology and Physiological Psychology"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040282257285571840","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"26560282"},{"@type":"JGN","@value":"JP26560282"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26560282/"}],"notation":[{"@language":"ja","@value":"随意運動に関わる脊髄神経機構に可塑性を促す神経リハビリテーション法の開発"},{"@language":"en","@value":"Motor imagery with muscle afferent stimulation elicits the voluntary-like reflex movement after its training."}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360285712529447424","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Convergence in Reflex Pathways from Multiple Cutaneous Nerves Innervating the Foot 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