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This technology has made it possible to obtain pluripotent stem cells from individuals with genetic disorders. Because iPSCs carry the identical genetic anomalies related to those disorders, iPSCs are an ideal platform for medical research. The pathophysiological cellular phenotypes of genetically heritable heart diseases such as arrhythmias and cardiomyopathies, have been modeled on cell culture dishes using disease-specific iPSC-derived cardiomyocytes. These model systems can potentially provide new insights into disease mechanisms and drug discoveries. This review focuses on recent progress in cardiovascular disease modeling using iPSCs, and discusses problems and future perspectives concerning their use.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380004239492721024","@type":"Researcher","foaf:name":[{"@value":"Atsushi Tanaka"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, 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