Involvement of a<i>Magnaporthe grisea</i>Serine/Threonine Kinase Gene, Mg<i>ATG1</i>, in Appressorium Turgor and Pathogenesis

DOI Web Site 8 Citations
  • Xiao-Hong Liu
    Biotechnology Institute, Zhejiang University, Kaixuan Road 268, Hangzhou 310029, China
  • Jian-Ping Lu
    College of Life Sciences, Zhejiang University, Yuhangtang Road 388, Hangzhou 310058, China
  • Lei Zhang
    College of Life Sciences, Zhejiang University, Yuhangtang Road 388, Hangzhou 310058, China
  • Fu-Cheng Lin
    Biotechnology Institute, Zhejiang University, Kaixuan Road 268, Hangzhou 310029, China
  • Bo Dong
    Biotechnology Institute, Zhejiang University, Kaixuan Road 268, Hangzhou 310029, China
  • Hang Min
    College of Life Sciences, Zhejiang University, Yuhangtang Road 388, Hangzhou 310058, China

Bibliographic Information

Published
2007-06
Rights Information
  • https://journals.asm.org/non-commercial-tdm-license
DOI
  • 10.1128/ec.00011-07
Publisher
American Society for Microbiology

Search this article

Description

<jats:title>ABSTRACT</jats:title><jats:p>We isolated an Mg<jats:italic>ATG1</jats:italic>gene encoding a serine/threonine protein kinase from the rice blast fungus<jats:italic>Magnaporthe grisea</jats:italic>. In the ΔMg<jats:italic>atg1</jats:italic>mutant, in which the Mg<jats:italic>ATG1</jats:italic>gene had been deleted, autophagy was blocked; the mutant also showed fewer lipid droplets in its conidia, lower turgor pressure of the appressorium, and such defects in morphogenesis as delayed initiation and slower germination of conidia. As a result of lower turgor pressure of the appressorium, the ΔMg<jats:italic>atg1</jats:italic>mutant lost its ability to penetrate and infect the two host plants, namely, rice and barley. However, normal values of the parameters and infective abilities were restored on reintroducing an intact copy of the Mg<jats:italic>ATG1</jats:italic>gene into the mutant. Autophagy is thus necessary for turnover of organic matter during the formation of conidia and appressoria and for normal development and pathogenicity in<jats:italic>M. grisea</jats:italic>.</jats:p>

Journal

  • Eukaryotic Cell

    Eukaryotic Cell 6 (6), 997-1005, 2007-06

    American Society for Microbiology

Citations (8)*help

See more

Details 詳細情報について

Report a problem

Back to top