{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360021390562771584.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1177/15500594231204174"}},{"identifier":{"@type":"URI","@value":"https://journals.sagepub.com/doi/pdf/10.1177/15500594231204174"}},{"identifier":{"@type":"URI","@value":"https://journals.sagepub.com/doi/full-xml/10.1177/15500594231204174"}},{"identifier":{"@type":"PMID","@value":"37844609"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Resting-state Electroencephalography Microstates Correlate with Pain Intensity in Patients with Complex Regional Pain Syndrome"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p> Objective: Severe pain and other symptoms in complex regional pain syndrome (CRPS), such as allodynia and hyperalgesia, are associated with abnormal resting-state brain network activity. No studies to date have examined resting-state brain networks in CRPS patients using electroencephalography (EEG), which can clarify the temporal dynamics of brain networks. Methods: We conducted microstate analysis using resting-state EEG signals to prospectively reveal direct correlations with pain intensity in CRPS patients (n = 17). Five microstate topographies were fitted back to individual CRPS patients’ EEG data, and temporal microstate measures were subsequently calculated. Results: Our results revealed five distinct microstates, termed microstates A to E, from resting EEG data in patients with CRPS. Microstates C, D and E were significantly correlated with pain intensity before pain treatment. Particularly, microstates D and E were significantly improved together with pain alleviation after pain treatment. As microstates D and E in the present study have previously been related to attentional networks and the default mode network, improvement in these networks might be related to pain relief in CRPS patients. Conclusions: The functional alterations of these brain networks affected the pain intensity of CRPS patients. Therefore, EEG microstate analyses may be used to identify surrogate markers for pain intensity. </jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380021390562771587","@type":"Researcher","foaf:name":[{"@value":"Michihiro Osumi"}],"jpcoar:affiliationName":[{"@value":"Graduate School of Health Science, Kio University. 4-2-2 Umaminaka, Kitakatsuragigun, Nara, Japan"},{"@value":"Neurorehabilitation Research Center, Kio University. 4-2-2 Umaminaka, Kitakatsuragigun, Nara, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021390562771588","@type":"Researcher","foaf:name":[{"@value":"Masahiko Sumitani"}],"jpcoar:affiliationName":[{"@value":"Department of Pain and Palliative Medicine, The University of Tokyo Hospital. 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1420845751145444096","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"90635567"},{"@type":"NRID","@value":"1000090635567"},{"@type":"NRID","@value":"9000413773885"},{"@type":"NRID","@value":"9000346962884"},{"@type":"NRID","@value":"9000406403261"},{"@type":"NRID","@value":"9000242544986"},{"@type":"NRID","@value":"9000367054369"},{"@type":"NRID","@value":"9000001535693"},{"@type":"NRID","@value":"9000242545065"},{"@type":"NRID","@value":"9000351083334"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/7000016522"}],"foaf:name":[{"@value":"Katsuyuki Iwatsuki"}],"jpcoar:affiliationName":[{"@value":"Department of Hand Surgery, Graduate School of Medicine, Nagoya University, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 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