{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360021390572036608.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1097/cej.0000000000000801"}},{"identifier":{"@type":"URI","@value":"https://journals.lww.com/10.1097/CEJ.0000000000000801"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Seaweed consumption and the risk of prostate cancer: the Miyagi cohort study"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Some laboratory studies have shown that fucoidan, which is contained in seaweed extract, has inhibitory effects on the invasion and angiogenesis of tumor cells; however, the association between seaweed consumption and prostate cancer incidence remains unclear. The purpose of the present study was to examine the association between seaweed consumption and the risk of prostate cancer incidence in the Japanese population. Data from 19 311 men in the Miyagi Cohort Study who were 40–64 years old at baseline in 1990 were examined. Seaweed consumption was assessed at baseline using a self-administered food frequency questionnaire. The participants were divided into three categories based on seaweed consumption at baseline. During 24.5 years of follow-up, we identified 815 incident cases of prostate cancer. Multivariate analysis showed that seaweed consumption was not associated with prostate cancer incidence. The multivariate hazard ratios and 95% confidence intervals for prostate cancer incidence in the highest tertile versus the other tertiles were 0.76 (0.60–0.96) and 0.78 (0.61–0.99) (<jats:italic toggle=\"yes\">P</jats:italic>-trend = 0.15). Furthermore, the null association was independent of whether their clinical stage was localized or advanced. In this population-based prospective cohort study conducted in Japan, we found no significant association between seaweed consumption and the incidence of prostate cancer.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380021390572036631","@type":"Researcher","foaf:name":[{"@value":"Koichi Matsumoto"}],"jpcoar:affiliationName":[{"@value":"Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021390572036611","@type":"Researcher","foaf:name":[{"@value":"Yumi Sugawara"}],"jpcoar:affiliationName":[{"@value":"Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021390572036610","@type":"Researcher","foaf:name":[{"@value":"Toshimasa Sone"}],"jpcoar:affiliationName":[{"@value":"Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021390572036613","@type":"Researcher","foaf:name":[{"@value":"Seiki Kanemura"}],"jpcoar:affiliationName":[{"@value":"Division of Cancer Epidemiology and Prevention, Miyagi Prefectural Cancer Research Center, Natori"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021390572036614","@type":"Researcher","foaf:name":[{"@value":"Akira Fukao"}],"jpcoar:affiliationName":[{"@value":"Miyagi Cancer Society, Sendai, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021390572036628","@type":"Researcher","foaf:name":[{"@value":"Ichiro Tsuji"}],"jpcoar:affiliationName":[{"@value":"Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09598278"}],"prism:publicationName":[{"@value":"European Journal of Cancer Prevention"}],"dc:publisher":[{"@value":"Ovid Technologies (Wolters Kluwer Health)"}],"prism:publicationDate":"2023-04-10","prism:volume":"32","prism:number":"5","prism:startingPage":"423","prism:endingPage":"430"},"reviewed":"false","url":[{"@id":"https://journals.lww.com/10.1097/CEJ.0000000000000801"}],"createdAt":"2023-04-11","modifiedAt":"2025-05-27","project":[{"@id":"https://cir.nii.ac.jp/crid/1040854882528043392","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"22K01977"},{"@type":"JGN","@value":"JP22K01977"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K01977/"}],"notation":[{"@language":"ja","@value":"災害被災者の精神的健康に働きかける地域での対人交流プログラムの開発"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360002218928187520","@type":"Article","resourceType":"学術雑誌論文(journal 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2010"}]},{"@id":"https://cir.nii.ac.jp/crid/1360302870458220160","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Characterization and screening of anti-tumor activity of fucoidan from acid-processed hijiki (Hizikia fusiforme)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360302871125254656","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Statistical review of US macronutrient consumption data, 1965–2011: Americans have been following dietary guidelines, coincident with the rise in obesity"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574093670968192","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cancer incidence and incidence rates in Japan in 2009: a study of 32 population-based cancer registries for the Monitoring of Cancer Incidence in Japan (MCIJ) 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