{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360021391883278848.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1038/s41598-023-44138-y"}},{"identifier":{"@type":"URI","@value":"https://www.nature.com/articles/s41598-023-44138-y.pdf"}},{"identifier":{"@type":"URI","@value":"https://www.nature.com/articles/s41598-023-44138-y"}},{"identifier":{"@type":"PMID","@value":"37828047"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Prognostic impact of the cross-sectional area of the erector spinae muscle in patients with pleuroparenchymal fibroelastosis"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title>\n                  <jats:p>\n                    Pleuroparenchymal fibroelastosis (PPFE) progresses slowly but sometimes relatively quickly, leading to decreased activities of daily living (ADL) and muscle weakness. Skeletal muscle atrophy and muscle weakness in chronic obstructive pulmonary disease (COPD) patients may be caused by cachexia and are associated with reduced ADLs and increased risk of death. However, the association between skeletal muscle mass and the prognosis of PPFE patients remains unknown. We retrospectively analysed the clinical significance of the cross-sectional area of the erector spinae muscle (ESM\n                    <jats:sub>CSA</jats:sub>\n                    ), a skeletal muscle index, and predictors of mortality within 3 years in PPFE 51 patients, idiopathic pulmonary fibrosis (IPF) 52 patients and COPD 62 patients. PPFE patients had significantly lower ESM\n                    <jats:sub>CSA</jats:sub>\n                    than IPF or COPD patients, and lower ESM\n                    <jats:sub>CSA</jats:sub>\n                    (< 22.57 cm\n                    <jats:sup>2</jats:sup>\n                    ) was associated with prognosis within 3 years (log-rank test; p = 0.006), whereas lower body mass index (BMI) showed no association. Multivariate analysis showed that ESM\n                    <jats:sub>CSA</jats:sub>\n                    was an independent predictor of mortality within 3 years in PPFE patients (hazard ratio, 0.854; 95% confidence interval: 0.737–0.990, p = 0.036). These results suggest the importance of monitoring ESM\n                    <jats:sub>CSA</jats:sub>\n                    in PPFE patients and that assessing ESM\n                    <jats:sub>CSA</jats:sub>\n                    in PPFE patients could be a more useful prognostic indicator than BMI.\n                  </jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380021391883278863","@type":"Researcher","foaf:name":[{"@value":"Shinsuke Kitahara"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021391883278856","@type":"Researcher","foaf:name":[{"@value":"Mitsuhiro Abe"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021391883278874","@type":"Researcher","foaf:name":[{"@value":"Chiyoko Kono"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021391883278982","@type":"Researcher","foaf:name":[{"@value":"Noriko Sakuma"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021391883278986","@type":"Researcher","foaf:name":[{"@value":"Daisuke Ishii"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021391883278859","@type":"Researcher","foaf:name":[{"@value":"Takeshi Kawasaki"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021391883278988","@type":"Researcher","foaf:name":[{"@value":"Jun Ikari"}]},{"@id":"https://cir.nii.ac.jp/crid/1380021391883278979","@type":"Researcher","foaf:name":[{"@value":"Takuji Suzuki"}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"20452322"}],"prism:publicationName":[{"@value":"Scientific Reports"}],"dc:publisher":[{"@value":"Springer Science and Business Media LLC"}],"prism:publicationDate":"2023-10-12","prism:volume":"13","prism:number":"1"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","dc:rights":["https://creativecommons.org/licenses/by/4.0","https://creativecommons.org/licenses/by/4.0"],"url":[{"@id":"https://www.nature.com/articles/s41598-023-44138-y.pdf"},{"@id":"https://www.nature.com/articles/s41598-023-44138-y"}],"createdAt":"2023-10-12","modifiedAt":"2023-11-18","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Muscle%20Weakness","dc:title":"Muscle Weakness"},{"@id":"https://cir.nii.ac.jp/all?q=Science","dc:title":"Science"},{"@id":"https://cir.nii.ac.jp/all?q=Q","dc:title":"Q"},{"@id":"https://cir.nii.ac.jp/all?q=R","dc:title":"R"},{"@id":"https://cir.nii.ac.jp/all?q=Paraspinal%20Muscles","dc:title":"Paraspinal Muscles"},{"@id":"https://cir.nii.ac.jp/all?q=Prognosis","dc:title":"Prognosis"},{"@id":"https://cir.nii.ac.jp/all?q=Article","dc:title":"Article"},{"@id":"https://cir.nii.ac.jp/all?q=Idiopathic%20Pulmonary%20Fibrosis","dc:title":"Idiopathic Pulmonary Fibrosis"},{"@id":"https://cir.nii.ac.jp/all?q=Pulmonary%20Disease,%20Chronic%20Obstructive","dc:title":"Pulmonary Disease, Chronic Obstructive"},{"@id":"https://cir.nii.ac.jp/all?q=Activities%20of%20Daily%20Living","dc:title":"Activities of Daily Living"},{"@id":"https://cir.nii.ac.jp/all?q=Medicine","dc:title":"Medicine"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Retrospective%20Studies","dc:title":"Retrospective Studies"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040299826879639168","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"23K24337"},{"@type":"JGN","@value":"JP23K24337"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K24337/"}],"notation":[{"@language":"ja","@value":"肺の恒常性維持・生体防御・組織修復を標的とした難治性呼吸器疾患治療法の開発と応用"},{"@language":"en","@value":"Novel therapeutic strategy of homeostasis, host defense and tissue regeneration in lung"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360004230069804800","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Anamorelin (ONO‐7643) for the treatment of patients with non–small cell lung cancer and cachexia: Results from a randomized, double‐blind, placebo‐controlled, multicenter study of Japanese patients (ONO‐7643‐04)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004232477967232","@type":"Article","resourceType":"学術雑誌論文(journal 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An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management"},{"@value":"An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence‐based guidelines for diagnosis and management"},{"@value":"On behalf of the ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis. 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