{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360290617878752256.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1021/jacs.0c11437"}},{"identifier":{"@type":"URI","@value":"https://pubs.acs.org/doi/pdf/10.1021/jacs.0c11437"}},{"identifier":{"@type":"PMID","@value":"33337857"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Metal-Dependent DNA Base Pairing of 5-Carboxyuracil with Itself and All Four Canonical Nucleobases"}],"description":[{"notation":[{"@value":"A 5-carboxyuracil (caU) nucleobase was found to pair not only with A (caU-A) by hydrogen bonding but also with other DNA nucleobases by metal coordination bonding. Metal-dependent formation of caU-Cu"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420282801211814272","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70508598"},{"@type":"NRID","@value":"1000070508598"},{"@type":"NRID","@value":"9000019073914"},{"@type":"NRID","@value":"9000283323303"},{"@type":"NRID","@value":"9000350668695"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/yusuketakezawa"}],"foaf:name":[{"@value":"Yusuke Takezawa"}],"jpcoar:affiliationName":[{"@value":"Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380290617878752385","@type":"Researcher","foaf:name":[{"@value":"Akira Suzuki"}],"jpcoar:affiliationName":[{"@value":"Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380290617878752384","@type":"Researcher","foaf:name":[{"@value":"Manabu Nakaya"}],"jpcoar:affiliationName":[{"@value":"Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380290617878752386","@type":"Researcher","foaf:name":[{"@value":"Kotaro Nishiyama"}],"jpcoar:affiliationName":[{"@value":"Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1420564276175832320","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"60187333"},{"@type":"NRID","@value":"1000060187333"},{"@type":"NRID","@value":"9000259336393"},{"@type":"NRID","@value":"9000412231136"},{"@type":"NRID","@value":"9000406560031"},{"@type":"NRID","@value":"9000255703476"},{"@type":"NRID","@value":"9000350668697"},{"@type":"NRID","@value":"9000412056403"},{"@type":"NRID","@value":"9000258731277"}],"foaf:name":[{"@value":"Mitsuhiko Shionoya"}],"jpcoar:affiliationName":[{"@value":"Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00027863"},{"@type":"EISSN","@value":"15205126"}],"prism:publicationName":[{"@value":"Journal of the American Chemical Society"}],"dc:publisher":[{"@value":"American Chemical Society (ACS)"}],"prism:publicationDate":"2020-12-18","prism:volume":"142","prism:number":"52","prism:startingPage":"21640","prism:endingPage":"21644"},"reviewed":"false","dc:rights":["https://doi.org/10.15223/policy-029","https://doi.org/10.15223/policy-037","https://doi.org/10.15223/policy-045"],"url":[{"@id":"https://pubs.acs.org/doi/pdf/10.1021/jacs.0c11437"}],"createdAt":"2020-12-18","modifiedAt":"2023-04-25","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Models,%20Molecular","dc:title":"Models, Molecular"},{"@id":"https://cir.nii.ac.jp/all?q=Metals,%20Heavy","dc:title":"Metals, Heavy"},{"@id":"https://cir.nii.ac.jp/all?q=Nucleic%20Acid%20Hybridization","dc:title":"Nucleic Acid Hybridization"},{"@id":"https://cir.nii.ac.jp/all?q=Hydrogen%20Bonding","dc:title":"Hydrogen Bonding"},{"@id":"https://cir.nii.ac.jp/all?q=DNA","dc:title":"DNA"},{"@id":"https://cir.nii.ac.jp/all?q=Uracil","dc:title":"Uracil"},{"@id":"https://cir.nii.ac.jp/all?q=Base%20Pairing","dc:title":"Base Pairing"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040282256879687296","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"16H06509"},{"@type":"JGN","@value":"JP16H06509"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-16H06509/"}],"notation":[{"@language":"ja","@value":"金属中心キラリティーの精密制御に基づく配位アシンメトリーの新展開"},{"@language":"en","@value":"New Development of Coordination Asymmetry Based on Precise Control of Metal Centered Chirality"}]},{"@id":"https://cir.nii.ac.jp/crid/1040282256904516096","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"16K21733"},{"@type":"JGN","@value":"JP16K21733"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-INTERNATIONAL-16K21733/"}],"notation":[{"@language":"ja","@value":"配位アシンメトリー：非対称配位圏設計と異方集積化が拓く新物質科学"},{"@language":"en","@value":"Coordination Asymmetry: Design of Asymmetric Coordination Sphere and Anisotropic Assembly for the Creation of Functional Molecules"}]},{"@id":"https://cir.nii.ac.jp/crid/1040282256969729280","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"18H02081"},{"@type":"JGN","@value":"JP18H02081"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H02081/"}],"notation":[{"@language":"ja","@value":"酵素反応を駆使した金属イオン応答性DNA超分子の創製"},{"@language":"en","@value":"Development of metal-responsive DNA supramolecules based on enzymatic DNA synthesis"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050016107290419712","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Functionalization of acyclic xenonucleic acid with modified nucleobases"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011143549450240","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mercury<sup>II</sup>-Mediated Formation of Thymine−Hg<sup>II</sup>−Thymine Base Pairs in DNA Duplexes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285707160508288","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"pH-Dependence of the thermal stability of metallo-DNA duplexes containing ligand-type 5-hydroxyuracil nucleobases"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619360921472","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Recent developments in reversible photoregulation of oligonucleotide structure and function"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620309494784","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"DNA nanomachines"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292621300721408","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Programmable self-assembly of metal ions inside artificial DNA duplexes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294646997604224","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Sharp Switching of DNAzyme Activity through the Formation of a Cu<sup>II</sup>‐Mediated Carboxyimidazole Base Pair"}]},{"@id":"https://cir.nii.ac.jp/crid/1360306904389160192","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Enzymatic synthesis of ligand-bearing oligonucleotides for the development of metal-responsive DNA materials"}]},{"@id":"https://cir.nii.ac.jp/crid/1360306906067517184","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Rational design of metal-responsive functional DNA supramolecules"}]},{"@id":"https://cir.nii.ac.jp/crid/1360306906072760832","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Ligase-mediated synthesis of Cu<sup>II</sup>-responsive allosteric DNAzyme with bifacial 5-carboxyuracil nucleobases"}]},{"@id":"https://cir.nii.ac.jp/crid/1360572092855454848","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Allosteric Regulation of DNAzyme Activities through Intrastrand Transformation Induced by Cu(II)-Mediated Artificial Base Pairing"}]},{"@id":"https://cir.nii.ac.jp/crid/1360572092857364096","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Site-specific polymerase incorporation of consecutive ligand-containing nucleotides for multiple metal-mediated base pairing"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095545309696","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Synthesis of Oligonucleotides Containing 5-Carboxy-2‘-deoxyuridine at Defined Sites"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576148815184384","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal-mediated DNA base pairing of easily prepared 2-oxo-imidazole-4-carboxylate nucleotides"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580232428468864","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Cu<sup>II</sup>-mediated stabilisation of DNA duplexes bearing consecutive ethenoadenine lesions and its application to a metal-responsive DNAzyme"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846641548643968","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Metal-Mediated DNA Base Pairing: Alternatives to Hydrogen-Bonded Watson–Crick Base Pairs"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848654922771200","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Bifacial Base‐Pairing Behaviors of 5‐Hydroxyuracil DNA Bases through Hydrogen Bonding and Metal Coordination"}]},{"@id":"https://cir.nii.ac.jp/crid/1360853567834119040","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal-responsive reversible binding of triplex-forming oligonucleotides with 5-hydroxyuracil nucleobases"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861705595185280","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal-dependent base pairing of bifacial iminodiacetic acid-modified uracil bases for switching DNA hybridization partner"}]},{"@id":"https://cir.nii.ac.jp/crid/1360865815509538304","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal-mediated DNA strand displacement and molecular device operations based on base-pair switching of 5-hydroxyuracil nucleobases"}]},{"@id":"https://cir.nii.ac.jp/crid/1361131418000330368","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Enzymatic Synthesis of Cu(II)-Responsive Deoxyribozymes through Polymerase Incorporation of Artificial Ligand-Type Nucleotides"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044014020352","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Allosterically Tunable, DNA-Based Switches Triggered by Heavy Metals"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044134062336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"DNA Architectonics: towards the Next Generation of Bio‐inspired Materials"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418519600922752","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Specific interactions between silver(i) ions and cytosine–cytosine pairs in DNA duplexes"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699996358679552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Optochemical Control of Deoxyoligonucleotide Function via a Nucleobase-Caging Approach"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981468957770368","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Controlled Stacking of 10 Transition‐Metal Ions inside a DNA Duplex"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469144752128","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Coordinating properties of isoorotic acid"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262943350531712","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The N(7),O(6) chelation mode of 6-oxopurines. Preparation and structure of (N-salicylidene-N',N'-dimethylethylenediamine)(theophyllinato)copper(II)-3.5-water"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944883075840","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Metal‐Modified Nucleic Acids: Metal‐Mediated Base Pairs, Triples, and Tetrads"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262945315952000","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Folding DNA to create nanoscale shapes and patterns"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893428187136","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Rational Design of “Turn‐On” Allosteric DNAzyme Catalytic Beacons for Aqueous Mercury Ions with Ultrahigh Sensitivity and Selectivity"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893765075840","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A Discrete Self-Assembled Metal Array in Artificial DNA"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895147837184","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The reversible reaction of Hg (II) and double-stranded polynucleotides a step-function theory and its significance"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895446196480","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mercury(II) Site-Selective Binding to a DNA Hairpin. Relationship of Sequence-Dependent Intra- and Interstrand Cross-Linking to the Hairpin−Duplex Conformational Transition"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895553233792","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nucleic acid duplexes with metal-mediated base pairs and their structures"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369898313344","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Trimethylplatinum‐Theophylline Hexamer: A Novel Pt<sub>6</sub> Heterocycle Containing Both PtN and PtO Bonds"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844060347776","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Analysis of Platinum Adducts with DNA Nucleotides and Nucleosides by Capillary Electrophoresis Coupled to ESI‐MS: Indications of Guanosine 5′‐Monophosphate <i>O</i><sup>6</sup>–<i>N</i>7 Chelation"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844346937344","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Observation of a direct interaction between the carbonyl oxygen, O(6), of a N(7)-bonded 6-oxopurine and a metal center. Preparation and crystal and molecular structure of (N-3,4-benzosalicylidene-N',N'-dimethylethylenediamine)(theophyllinato)copper(II) monohydrate"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844794910080","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ion-induced DNAzyme switches"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844936906880","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Self-Assemblies Based on Metal-Mediated Artificial Nucleobase Pairing"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845750525312","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"DNA nanotechnology"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670319420799872","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Solution structure of a DNA double helix with consecutive metal-mediated base pairs"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670320576034304","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"New Synthesis of 5-Carboxy-2′-deoxyuridine and Its Incorporation into Synthetic Oligonucleotides"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270983141632","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mechanisms of Base Selection by Human Single-stranded Selective Monofunctional Uracil-DNA Glycosylase"}]},{"@id":"https://cir.nii.ac.jp/crid/2050025942141186048","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Artificial DNA base pairing mediated by diverse metal ions"}]},{"@id":"https://cir.nii.ac.jp/crid/2051151842048028672","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Chemically caged nucleic acids"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1021/jacs.0c11437"},{"@type":"KAKEN","@value":"PRODUCT-23768005"},{"@type":"KAKEN","@value":"PRODUCT-23731763"},{"@type":"KAKEN","@value":"PRODUCT-23410185"},{"@type":"OPENAIRE","@value":"doi_dedup___::29bcd4a12be0f0042be0993b321390fa"},{"@type":"CROSSREF","@value":"10.1039/d4ob00947a_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1007/s10847-024-01224-6_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1039/d3sc05042d_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1039/d0cc07771b_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1039/d2sc00926a_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1038/s41428-023-00776-7_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1039/d2cc06179a_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1039/d1cc00553g_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1039/d2sc06534g_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"},{"@type":"CROSSREF","@value":"10.1038/s41467-023-40353-3_references_DOI_Y0gbjXR1N6P8b9f5Il8nHPRWctj"}]}