Outcomes associated with intra-arrest hyperoxaemia in out-of-hospital cardiac arrest: A registry-based cohort study

Bibliographic Information

Published
2022-12
Resource Type
journal article
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  • https://www.elsevier.com/tdm/userlicense/1.0/
  • https://www.elsevier.com/legal/tdmrep-license
  • https://doi.org/10.15223/policy-017
  • https://doi.org/10.15223/policy-037
  • https://doi.org/10.15223/policy-012
  • https://doi.org/10.15223/policy-029
  • https://doi.org/10.15223/policy-004
DOI
  • 10.1016/j.resuscitation.2022.11.008
Publisher
Elsevier BV

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Description

An association between post-arrest hyperoxaemia and worse outcomes has been reported for out-of-hospital cardiac arrest (OHCA) patients, but little is known about the relationship between intra-arrest hyperoxaemia and clinically relevant outcomes. This study aimed to investigate the association between intra-arrest hyperoxaemia and outcomes for OHCA patients.This was an observational study using a registry database of OHCA cases that occurred between 2014 and 2017 in Japan. We included adult, non-traumatic OHCA patients who were in cardiac arrest at the time of hospital arrival and for whom partial pressure of arterial oxygen (PaOAmong 16,013 patients who met the eligibility criteria, the proportion of favourable functional survival increased as the PaOIn this observational study of adult OHCA patients, intra-arrest normoxaemia and hyperoxaemia were associated with better functional survival, compared to hypoxaemia.

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