{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360301166320820608.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1111/aor.12191"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Faor.12191"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/aor.12191"}},{"identifier":{"@type":"PMID","@value":"24117701"}}],"dc:title":[{"@value":"Extracorporeal Life Support After Cardiac Surgery in Children: Outcomes From a Single Institution"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>Extracorporeal life support (<jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content>) is used after congenital heart surgery for several indications, including failure to separate from cardiopulmonary bypass, postoperative low cardiac output syndrome, and extracorporeal cardiopulmonary resuscitation. Here, we assessed the outcomes of <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content> in children after cardiac surgery at our institution. Medical records of all children who required postoperative <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content> at our institution were reviewed. Between 2003 and 2011, 36 (1.4%) of 2541 pediatric cardiac surgical cases required postoperative <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content>. Median age of patients was 64 days (range: 0 days–4.1 years). <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content> was in the form of either extracorporeal membrane oxygenation (<jats:styled-content style=\"fixed-case\">ECMO</jats:styled-content>; <jats:italic>n</jats:italic> = 24) or ventricular assist system (<jats:styled-content style=\"fixed-case\">VAS</jats:styled-content>; <jats:italic>n</jats:italic> = 12). Mean duration of <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content> was 4.9 ± 4.2 days. Overall, 21 patients (58%) were weaned off <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content>, and 17 patients (47%) were successfully discharged from the hospital. Patients with biventricular heart (<jats:styled-content style=\"fixed-case\">BVH</jats:styled-content>) had higher survival‐to‐hospital discharge rates compared with those with univentricular heart (<jats:styled-content style=\"fixed-case\">UVH</jats:styled-content>) (<jats:italic>P</jats:italic> = 0.019). Regarding <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content> type, <jats:styled-content style=\"fixed-case\">UVH</jats:styled-content> patients who received <jats:styled-content style=\"fixed-case\">VAS</jats:styled-content> showed higher rates of device discontinuation than <jats:styled-content style=\"fixed-case\">UVH</jats:styled-content> patients who received <jats:styled-content style=\"fixed-case\">ECMO</jats:styled-content> (<jats:italic>P</jats:italic> = 0.012). However, rates of hospital discharge were not significantly different between <jats:styled-content style=\"fixed-case\">UVH</jats:styled-content> patients who received <jats:styled-content style=\"fixed-case\">VAS</jats:styled-content> or <jats:styled-content style=\"fixed-case\">ECMO</jats:styled-content>. Surgical interventions, such as banding of <jats:styled-content style=\"fixed-case\">B</jats:styled-content>lalock–<jats:styled-content style=\"fixed-case\">T</jats:styled-content>aussig shunt to reduce pulmonary blood flow or placing bidirectional cavopulmonary shunt to minimize ventricular volume overload, were effective for weaning off <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content> in patients with <jats:styled-content style=\"fixed-case\">UVH</jats:styled-content>. <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content> is beneficial to children with low cardiac output after cardiac surgery. Rates of survival‐to‐hospital discharge were higher in <jats:styled-content style=\"fixed-case\">BVH</jats:styled-content> patients than <jats:styled-content style=\"fixed-case\">UVH</jats:styled-content> patients. Additional interventions to reduce ventricular volume load may be effective for discontinuing <jats:styled-content style=\"fixed-case\">ECLS</jats:styled-content> in patients with <jats:styled-content style=\"fixed-case\">UVH</jats:styled-content>.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380301166320820610","@type":"Researcher","foaf:name":[{"@value":"Takashi Sasaki"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Surgery Kanagawa Children's Medical Center  Yokohama Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380301166320820613","@type":"Researcher","foaf:name":[{"@value":"Toshihide Asou"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Surgery Kanagawa Children's Medical Center  Yokohama Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380301166320820611","@type":"Researcher","foaf:name":[{"@value":"Yuko Takeda"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Surgery Kanagawa Children's Medical Center  Yokohama Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380301166320820612","@type":"Researcher","foaf:name":[{"@value":"Yasuko Onakatomi"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Surgery Kanagawa Children's Medical Center  Yokohama Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380301166320820608","@type":"Researcher","foaf:name":[{"@value":"Takashi Tominaga"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Surgery Kanagawa Children's Medical Center  Yokohama Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380301166320820609","@type":"Researcher","foaf:name":[{"@value":"Yusuke Yamamoto"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Surgery Kanagawa Children's Medical Center  Yokohama Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"0160564X"},{"@type":"EISSN","@value":"15251594"}],"prism:publicationName":[{"@value":"Artificial Organs"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2013-10-14","prism:volume":"38","prism:number":"1","prism:startingPage":"34","prism:endingPage":"40"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Faor.12191"},{"@id":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/aor.12191"}],"createdAt":"2013-10-14","modifiedAt":"2023-09-26","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Heart%20Defects,%20Congenital","dc:title":"Heart Defects, Congenital"},{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Infant,%20Newborn","dc:title":"Infant, Newborn"},{"@id":"https://cir.nii.ac.jp/all?q=Infant","dc:title":"Infant"},{"@id":"https://cir.nii.ac.jp/all?q=Extracorporeal%20Membrane%20Oxygenation","dc:title":"Extracorporeal Membrane Oxygenation"},{"@id":"https://cir.nii.ac.jp/all?q=Treatment%20Outcome","dc:title":"Treatment Outcome"},{"@id":"https://cir.nii.ac.jp/all?q=Child,%20Preschool","dc:title":"Child, Preschool"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Heart-Assist%20Devices","dc:title":"Heart-Assist Devices"},{"@id":"https://cir.nii.ac.jp/all?q=Life%20Support%20Systems","dc:title":"Life Support Systems"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1390019204223720704","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Circulatory Support for Severe Heart Failure in Children"},{"@language":"ja","@value":"小児重症心不全に対する補助循環・補助人工心臓治療：先天性心疾患も含めて"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1111/aor.12191"},{"@type":"OPENAIRE","@value":"doi_dedup___::d8a109a809472eed15a6fc7b24a95ea2"},{"@type":"CROSSREF","@value":"10.9794/jspccs.39.161_references_DOI_VnVIGNiw28SQ5XybvggRvQW7m0J"}]}