Salt Effect on Stability and Solvation Structure of Peptide: An Integral Equation Study

DOI PDF 4 Citations 32 References
  • Takashi Imai
    Department of Functional Molecular Science, The Graduate University for Advanced Studies Okazaki, Aichi 444-8585
  • Masahiro Kinoshita
    Advanced Energy Utilization Division, Institute of Advanced Energy Uji, Kyoto 611-0011
  • Fumio Hirata
    Department of Theoretical Study, Institute for Molecular Science and Department of Functional Molecular Science, The Graduate University for Advanced Studies Okazaki, Aichi 444-8585

Bibliographic Information

Published
2000-05-01
Rights Information
  • https://academic.oup.com/pages/standard-publication-reuse-rights
DOI
  • 10.1246/bcsj.73.1113
Publisher
Oxford University Press (OUP)

Search this article

Description

<jats:title>Abstract</jats:title> <jats:p>Salt effects on the stability and on the solvation structure of a peptide in a variety of aqueous solutions of the alkali-halide ions are studied by means of the reference interaction site model (RISM) theory. The order of salt effect on the peptide stability is consistent with the experimental results; the order follows the Hofmeister series. The results are further analyzed in order to clarify the nature of the salt effect which determines the Hofmeister series and to find the reason why the Hofmeister series applies so generally to a variety of solutes in aqueous solutions. A heuristic model for explaining salt effects on the solvation structure of the peptide is proposed based on changes in the peptide-water pair correlation functions due to the ion perturbation.</jats:p>

Journal

Citations (4)*help

See more

References(32)*help

See more

Details 詳細情報について

Report a problem

Back to top