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Nonlinear concentration gradients regulated by the width of channels for observation of half maximal inhibitory concentration (IC<sub>50</sub>) of transporter proteins
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- Yuta Abe
- Kanagawa Academy of Science and Technology (KAST), KSP EAST 303, 3-2-1, Sakado, Takatsu-ku, Kawasaki, Kanagawa, Japan
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- Koki Kamiya
- Kanagawa Academy of Science and Technology (KAST), KSP EAST 303, 3-2-1, Sakado, Takatsu-ku, Kawasaki, Kanagawa, Japan
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- Toshihisa Osaki
- Kanagawa Academy of Science and Technology (KAST), KSP EAST 303, 3-2-1, Sakado, Takatsu-ku, Kawasaki, Kanagawa, Japan
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- Hirotaka Sasaki
- Kanagawa Academy of Science and Technology (KAST), KSP EAST 303, 3-2-1, Sakado, Takatsu-ku, Kawasaki, Kanagawa, Japan
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- Ryuji Kawano
- Kanagawa Academy of Science and Technology (KAST), KSP EAST 303, 3-2-1, Sakado, Takatsu-ku, Kawasaki, Kanagawa, Japan
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- Norihisa Miki
- Kanagawa Academy of Science and Technology (KAST), KSP EAST 303, 3-2-1, Sakado, Takatsu-ku, Kawasaki, Kanagawa, Japan
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- Shoji Takeuchi
- Kanagawa Academy of Science and Technology (KAST), KSP EAST 303, 3-2-1, Sakado, Takatsu-ku, Kawasaki, Kanagawa, Japan
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Description
<jats:p>We determine a probable IC<jats:sub>50</jats:sub> value of ABC transporter proteins by using a width-modulated nonlinear concentration gradient generator.</jats:p>
Journal
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- The Analyst
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The Analyst 140 (16), 5557-5562, 2015
Royal Society of Chemistry (RSC)
