{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360567184851574400.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1097/md.0000000000000405"}},{"identifier":{"@type":"URI","@value":"https://journals.lww.com/10.1097/MD.0000000000000405"}},{"identifier":{"@type":"PMID","@value":"25621687"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Simplified Classification of Capillary Pattern in Barrett Esophagus Using Magnifying Endoscopy With Narrow Band Imaging"}],"dcterms:alternative":[{"@value":"Implications for Malignant Potential and Interobserver Agreement"}],"description":[{"notation":[{"@value":"The classification of Barrett esophagus (BE) using magnifying endoscopy with narrow band imaging (ME-NBI) is not widely used in clinical settings because of its complexity. To establish a new simplified available classification using ME-NBI.We conducted a cross-sectional study in a single-referral center. One hundred eight consecutive patients with BE using ME-NBI and crystal violet (CV) chromoendoscopy, and histological findings were enrolled. BE areas observed by ME-NBI were classified as type I or II on the basis of capillary pattern (CP), and as closed or open type on the basis of a mucosal pit pattern using CV chromoendoscopy; then, biopsy samples were obtained. We evaluated the relation between CP and pit pattern, expression of the factors with malignant potential, percentage of microvascular density, and interobserver agreement.One hundred thirty lesions from 91 patients were analyzed. Type II CP had more open type pit pattern areas and significantly greater microvascular density than type I. The presence of dysplasia, specialized intestinal metaplasia, expressions of COX-2, CDX2, and CD34, and PCNA index were significantly higher in type II, whereas the multivariate analysis showed that type II was the best predictor for the presence of dysplasia (OR 11.14), CD34 expression (OR 3.60), and PCNA (OR 3.29). Interobserver agreement for this classification was substantial (κ = 0.66).A simplified CP classification based on observation with ME-NBI is presented. Our results indicate that the classification may be useful for surveillance of BE with high malignant potential."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380567184851574273","@type":"Researcher","foaf:name":[{"@value":"Yuji Tamagawa"}]},{"@id":"https://cir.nii.ac.jp/crid/1380567184851574406","@type":"Researcher","foaf:name":[{"@value":"Goichi Uno"}]},{"@id":"https://cir.nii.ac.jp/crid/1380567184851574400","@type":"Researcher","foaf:name":[{"@value":"Norihisa Ishimura"}]},{"@id":"https://cir.nii.ac.jp/crid/1380567184851574403","@type":"Researcher","foaf:name":[{"@value":"Yasumasa Tada"}]},{"@id":"https://cir.nii.ac.jp/crid/1380567184851574272","@type":"Researcher","foaf:name":[{"@value":"Shunji Ishihara"}]},{"@id":"https://cir.nii.ac.jp/crid/1380567184851574274","@type":"Researcher","foaf:name":[{"@value":"Takafumi Yuki"}]},{"@id":"https://cir.nii.ac.jp/crid/1380567184851574402","@type":"Researcher","foaf:name":[{"@value":"Takashi Matsushita"}]},{"@id":"https://cir.nii.ac.jp/crid/1380567184851574405","@type":"Researcher","foaf:name":[{"@value":"Riruke Maruyama"}]},{"@id":"https://cir.nii.ac.jp/crid/1380567184851574404","@type":"Researcher","foaf:name":[{"@value":"Yuji Amano"}]},{"@id":"https://cir.nii.ac.jp/crid/1420567172283931520","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"30243306"},{"@type":"NRID","@value":"1000030243306"},{"@type":"NRID","@value":"9000019240063"},{"@type":"NRID","@value":"9000000311551"},{"@type":"NRID","@value":"9000020618012"},{"@type":"NRID","@value":"9000283273504"},{"@type":"NRID","@value":"9000265249583"},{"@type":"NRID","@value":"9000001677634"},{"@type":"NRID","@value":"9000021734378"},{"@type":"NRID","@value":"9000001205043"},{"@type":"NRID","@value":"9000023336763"},{"@type":"NRID","@value":"9000020087237"},{"@type":"NRID","@value":"9000283421677"},{"@type":"NRID","@value":"9000283422652"},{"@type":"NRID","@value":"9000261014670"},{"@type":"NRID","@value":"9000010694468"},{"@type":"NRID","@value":"9000001470194"},{"@type":"NRID","@value":"9000020806762"},{"@type":"NRID","@value":"9000283423185"},{"@type":"NRID","@value":"9000001952190"},{"@type":"NRID","@value":"9000398302987"},{"@type":"NRID","@value":"9000020600803"},{"@type":"NRID","@value":"9000283494024"},{"@type":"NRID","@value":"9000001205118"},{"@type":"NRID","@value":"9000339141311"},{"@type":"NRID","@value":"9000347189152"},{"@type":"NRID","@value":"9000001816652"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0014797"}],"foaf:name":[{"@value":"Yoshikazu Kinoshita"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00257974"}],"prism:publicationName":[{"@value":"Medicine"}],"dc:publisher":[{"@value":"Ovid Technologies (Wolters Kluwer Health)"}],"prism:publicationDate":"2015-01","prism:volume":"94","prism:number":"3","prism:startingPage":"e405"},"reviewed":"false","url":[{"@id":"https://journals.lww.com/10.1097/MD.0000000000000405"}],"createdAt":"2015-01-24","modifiedAt":"2021-05-14","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Esophageal%20Neoplasms","dc:title":"Esophageal Neoplasms"},{"@id":"https://cir.nii.ac.jp/all?q=Biopsy","dc:title":"Biopsy"},{"@id":"https://cir.nii.ac.jp/all?q=Antigens,%20CD34","dc:title":"Antigens, CD34"},{"@id":"https://cir.nii.ac.jp/all?q=Barrett%20Esophagus","dc:title":"Barrett Esophagus"},{"@id":"https://cir.nii.ac.jp/all?q=Narrow%20Band%20Imaging","dc:title":"Narrow Band Imaging"},{"@id":"https://cir.nii.ac.jp/all?q=Esophagus","dc:title":"Esophagus"},{"@id":"https://cir.nii.ac.jp/all?q=Risk%20Factors","dc:title":"Risk Factors"},{"@id":"https://cir.nii.ac.jp/all?q=Proliferating%20Cell%20Nuclear%20Antigen","dc:title":"Proliferating Cell Nuclear Antigen"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=CDX2%20Transcription%20Factor","dc:title":"CDX2 Transcription Factor"},{"@id":"https://cir.nii.ac.jp/all?q=Aged","dc:title":"Aged"},{"@id":"https://cir.nii.ac.jp/all?q=4500","dc:title":"4500"},{"@id":"https://cir.nii.ac.jp/all?q=Homeodomain%20Proteins","dc:title":"Homeodomain Proteins"},{"@id":"https://cir.nii.ac.jp/all?q=Observer%20Variation","dc:title":"Observer Variation"},{"@id":"https://cir.nii.ac.jp/all?q=Endoscopy","dc:title":"Endoscopy"},{"@id":"https://cir.nii.ac.jp/all?q=Middle%20Aged","dc:title":"Middle Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Capillaries","dc:title":"Capillaries"},{"@id":"https://cir.nii.ac.jp/all?q=Cross-Sectional%20Studies","dc:title":"Cross-Sectional Studies"},{"@id":"https://cir.nii.ac.jp/all?q=Cyclooxygenase%202","dc:title":"Cyclooxygenase 2"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Biomarkers","dc:title":"Biomarkers"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040000782302850304","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"26460937"},{"@type":"JGN","@value":"JP26460937"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26460937/"}],"notation":[{"@language":"ja","@value":"Notchシグナル再活性化によるバレット食道の発癌・進展機序の解明"},{"@language":"en","@value":"Evaluation of reactivation of Notch signaling in the development and progression of adenocarcinoma in Barrett's esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1040282256808390016","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"15H04763"},{"@type":"JGN","@value":"JP15H04763"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H04763/"}],"notation":[{"@language":"ja","@value":"ラマン分光法を用いた，好酸球性食道炎の非生検診断法の開発"},{"@language":"en","@value":"The development of a Raman spectroscopic technique to diagnose Eosinophil Esophagitis  non-bioptically"}]},{"@id":"https://cir.nii.ac.jp/crid/1040282257235777152","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"25460928"},{"@type":"JGN","@value":"JP25460928"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25460928/"}],"notation":[{"@language":"ja","@value":"好酸球性食道炎の病態に及ぼす胃酸の影響についての研究"},{"@language":"en","@value":"Effect of gastric acid on the eosinophilic esophagitis"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050001202733270272","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification"}]},{"@id":"https://cir.nii.ac.jp/crid/1360001113980919808","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Barrett's esophagus with high-grade dysplasia: Focus on current treatment options"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004234897837696","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Fatty Acid Synthase Expression in Barrett's Esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011142934672640","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"An Endoscopic Recognition of the Atrophic Border and its Significance in Chronic Gastritis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011144012312192","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Narrow-band imaging with magnification in Barrett’s esophagus: validation of a simplified grading system of mucosal morphology patterns against histology"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011145824238080","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The ‘angiogenic switch’ in the progression from Barrett's metaplasia to esophageal adenocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011146558520192","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Clinical utility and interobserver agreement of autofluorescence imaging and magnification narrow-band imaging for the evaluation of Barrett's esophagus: a prospective tandem study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360290617410393472","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Is Malignant Potential of Barrett’s Esophagus Predictable by Endoscopy Findings?"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619646079104","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Role of hiatus hernia and gastric mucosal atrophy in the development of reflux esophagitis in the elderly"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619669345536","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Effects of Dropping the Requirement for Goblet Cells From the Diagnosis of Barrett's Esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620683352192","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Evaluation of microvascular density in Barrett's associated neoplasia"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292621292955904","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Role of Overdiagnosis and Reclassification in the Marked Increase of Esophageal Adenocarcinoma Incidence"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574093729818112","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"American Gastroenterological Association Technical Review on the Management of Barrett's Esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855568525874048","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mortality in Barrett’s esophagus: three decades of experience at a single center"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569311859200","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Zooming in on Barrett oesophagus using narrow-band imaging: an international observer agreement study"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044913643776","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Evaluation of modified crystal violet chromoendoscopy procedure using new mucosal pit pattern classification for detection of Barrett's dysplastic lesions"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045586682368","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Development and Validation of an Endoscopic Grading System for Barrett’s Esophagus: The Prague C & M Criteria"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045934067968","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Magnification chromoendoscopy for the detection of intestinal metaplasia and dysplasia in Barrett’s oesophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137046471558272","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Updated Guidelines 2008 for the Diagnosis, Surveillance and Therapy of Barrett's Esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418518640146944","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418519690355712","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Narrow band imaging for characterization of high grade dysplasia and specialized intestinal metaplasia in Barrett’s esophagus: a meta-analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520948334080","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Barrett's oesophagus with predominant intestinal metaplasia correlates with superficial cyclo‐oxygenase‐2 expression, increased proliferation and reduced apoptosis: changes that are partially reversed by non‐steroidal anti‐inflammatory drugs usage"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993356926208","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endoscopic assessment and grading of Barrett's esophagus using magnification endoscopy and narrow band imaging: Impact of structured learning and experience on the accuracy of the Amsterdam classification system"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993900613376","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Esophageal adenocarcinoma arising in Barrett esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994554812416","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Predictors for squamous re‐epithelialization of Barrett’s esophagus after endoscopic biopsy"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995092257536","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endotherapy versus surgery for early neoplasia in Barrett's esophagus: a meta-analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995214249344","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Crystal Violet Chromoendoscopy with Mucosal Pit Pattern Diagnosis is Useful for Surveillance of Short-Segment Barrett's Esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469918476800","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Time Trends of US Hospitalization for Esophageal Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981471314821760","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Prostaglandins and the Regulation of Tumor Growth"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944179027328","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Advanced Imaging Technologies Increase Detection of Dysplasia and Neoplasia in Patients With Barrett's Esophagus: A Meta-analysis and Systematic Review"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944401769088","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Long-term follow-up of Barrett's high-grade dysplasia"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944822900992","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Long-term outcomes of patients with Barrett's esophagus and high-grade dysplasia or early cancer treated with endoluminal therapies with intention to complete eradication"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544418508700672","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endoscopic diagnosis of early <scp>B</scp>arrett's neoplasia: <scp>P</scp>erspectives for advanced endoscopic technology"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544418682537344","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Diverging Trends in the Incidence of Reflux-related and Helicobacter pylori-related Gastric Cardia Cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544418843104512","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Does the Incidence of Adenocarcinoma of the Esophagus and Gastric Cardia Continue to Rise in the Twenty-First Century?—a SEER Database Analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825894494197888","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Two cases of superficial cancer in Barrett's esophagus detected by chromoendoscopy with crystal violet"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895029455232","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Standard endoscopy with random biopsies versus narrow band imaging targeted biopsies in Barrett's oesophagus: a prospective, international, randomised controlled trial"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895065383552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Gastrointestinal epithelial neoplasia: Vienna revisited"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895355834752","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Methylene blue selectively stains intestinal metaplasia in Barrett's esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895539856896","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Prevalence of and risk factors for Barrett's esophagus with intestinal predominant mucin phenotype"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107368305284736","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endoscopic assessment and grading of Barrett's esophagus using magnification endoscopy and narrow-band imaging: accuracy and interobserver agreement of different classification systems (with videos)"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369243211648","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The utility of a novel narrow band imaging endoscopy system in patients with Barrett's esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845107114496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Practice Guidelines on the Diagnosis, Surveillance, and Therapy of Barrett's Esophagus"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951794297464960","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Adherence to Biopsy Guidelines for Barrett's Esophagus Surveillance in the Community Setting in the United States"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951796084280832","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mucosal morphology in Barrett’s esophagus: interobserver agreement and role of narrow band imaging"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951796288291840","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Incipient Angiogenesis in Barrett’s Epithelium and Lymphangiogenesis in Barrett’s Adenocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233268969205248","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Detection and classification of the mucosal and vascular patterns (mucosal morphology) in Barrett's esophagus by using narrow band imaging"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270390344576","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Observer agreement in the assessment of narrowband imaging system surface patterns in Barrett’s esophagus: a multicenter study"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270392848768","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Classification of Barrett's epithelium by magnifying endoscopy"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270683166592","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Inflammation and Barrett's carcinogenesis"}]},{"@id":"https://cir.nii.ac.jp/crid/1374228030203636224","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Inhibition of cyclooxygenase-2 and activation of peroxisome proliferator-activated receptor-gamma synergistically induces apoptosis and inhibits growth of human breast cancer cells."}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1097/md.0000000000000405"},{"@type":"KAKEN","@value":"PRODUCT-15263007"},{"@type":"KAKEN","@value":"PRODUCT-20454101"},{"@type":"KAKEN","@value":"PRODUCT-20539458"},{"@type":"OPENAIRE","@value":"doi_dedup___::c07d0424e73f330ce937d2ba464c8ec8"},{"@type":"CROSSREF","@value":"10.3390/life10100244_references_DOI_2PQYG4H61AxfYDfPXkVzkNd926M"}]}