Simple and convenient synthesis of a fluorinated GM4 analogue

DOI Web Site Web Site 被引用文献3件

この論文をさがす

説明

Abstract A series of fluorinated galactosides, dodecyl 2-deoxy-2-fluoro-β- d -galactopyranoside (2F Gal), dodecyl 4-deoxy-4-fluoro-β- d -galactopyranoside (4F Gal) and dodecyl 6-deoxy-6-fluoro-β- d -galactopyranoside (6F Gal), was chemically synthesized and introduced to B16 cells to serve as scaffolds for cellular enzyme glycosylation. Results showed that the presence of fluorine exercised significant effects on cell viability. Among the fluorinated galactosides used, 2F Gal was glycosylated to afford a GM4 analogue.

収録刊行物

被引用文献 (3)*注記

もっと見る

問題の指摘

ページトップへ