Prevalence of newly isolated, cytopathic small round virus (Aichi strain) in Japan

DOI Web Site 7 Citations
  • T Yamashita
    Department of Virology, Aichi Prefectural Institute of Public Health, Nagoya, Japan.
  • K Sakae
    Department of Virology, Aichi Prefectural Institute of Public Health, Nagoya, Japan.
  • Y Ishihara
    Department of Virology, Aichi Prefectural Institute of Public Health, Nagoya, Japan.
  • S Isomura
    Department of Virology, Aichi Prefectural Institute of Public Health, Nagoya, Japan.
  • E Utagawa
    Department of Virology, Aichi Prefectural Institute of Public Health, Nagoya, Japan.

Bibliographic Information

Published
1993-11
Rights Information
  • https://journals.asm.org/non-commercial-tdm-license
DOI
  • 10.1128/jcm.31.11.2938-2943.1993
Publisher
American Society for Microbiology

Search this article

Description

<jats:p>Cytopathic small round virus (Aichi strain), isolated from a patient with oyster-associated gastroenteritis, showed no reaction in the polymerase chain reaction method for enteroviruses or in the enzyme-linked immunosorbent assay (ELISA) for the five serotypes of astroviruses. Our ELISA was sensitive in detecting the Aichi strain antigen in stool samples, but there was no reaction in this ELISA with any non-Aichi strains of enteric viruses, with such origins as enterovirus, rotavirus, Norwalk virus, calicivirus, or astrovirus. In the ELISA, 13 of 47 stool samples from adult patients in five of nine oyster-associated gastroenteritis outbreaks were positive, but only 1 of 397 pediatric stool samples in Aichi Prefecture was positive. The prevalence rate for Aichi strain antibody was found to be 7.2% for persons aged 7 months to 4 years. The prevalence rate for antibody to Aichi strain increased with age, to about 80% in persons 35 years old. On the basis of the results of the present study, it was hypothesized that Aichi strain could be a new type of small round virus that mainly produces diarrhea in patients in the 15- to 34-year-old age group, 50 to 76% of whom possess neutralizing antibody.</jats:p>

Journal

Citations (7)*help

See more

Details 詳細情報について

Report a problem

Back to top