{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360576118740094080.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3390/cells10112975"}},{"identifier":{"@type":"URI","@value":"https://www.mdpi.com/2073-4409/10/11/2975/pdf"}},{"identifier":{"@type":"PMID","@value":"34831198"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Trogocytosis in Unicellular Eukaryotes"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Trogocytosis is a mode of internalization of a part of a live cell by nibbling and is mechanistically distinct from phagocytosis, which implies internalization of a whole cell or a particle. Trogocytosis has been demonstrated in a broad range of cell types in multicellular organisms and is also known to be involved in a plethora of functions. In immune cells, trogocytosis is involved in the “cross-dressing” between antigen presenting cells and T cells, and is thus considered to mediate intercellular communication. On the other hand, trogocytosis has also been reported in a variety of unicellular organisms including the protistan (protozoan) parasite Entamoeba histolytica. E. histolytica ingests human T cell line by trogocytosis and acquires complement resistance and cross-dresses major histocompatibility complex (MHC) class I on the cell surface. Furthermore, trogocytosis and trogocytosis-like phenomena (nibbling of a live cell, not previously described as trogocytosis) have also been reported in other parasitic protists such as Trichomonas, Plasmodium, Toxoplasma, and free-living amoebae. Thus, trogocytosis is conserved in diverse eukaryotic supergroups as a means of intercellular communication. It is depicting the universality of trogocytosis among eukaryotes. In this review, we summarize our current understanding of trogocytosis in unicellular organisms, including the history of its discovery, taxonomical distribution, roles, and molecular mechanisms.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380576118740094209","@type":"Researcher","foaf:name":[{"@value":"Kumiko Nakada-Tsukui"}],"jpcoar:affiliationName":[{"@value":"Department of Parasitology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118740094336","@type":"Researcher","foaf:name":[{"@value":"Tomoyoshi Nozaki"}],"jpcoar:affiliationName":[{"@value":"Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8654, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"20734409"}],"prism:publicationName":[{"@value":"Cells"}],"dc:publisher":[{"@value":"MDPI AG"}],"prism:publicationDate":"2021-11-01","prism:volume":"10","prism:number":"11","prism:startingPage":"2975"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","dc:rights":["https://creativecommons.org/licenses/by/4.0/"],"url":[{"@id":"https://www.mdpi.com/2073-4409/10/11/2975/pdf"}],"createdAt":"2021-11-01","modifiedAt":"2025-10-11","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=QH573-671","dc:title":"QH573-671"},{"@id":"https://cir.nii.ac.jp/all?q=Entamoeba%20histolytica","dc:title":"Entamoeba histolytica"},{"@id":"https://cir.nii.ac.jp/all?q=phagocytosis","dc:title":"phagocytosis"},{"@id":"https://cir.nii.ac.jp/all?q=Eukaryota","dc:title":"Eukaryota"},{"@id":"https://cir.nii.ac.jp/all?q=unicellular%20eukaryotes","dc:title":"unicellular eukaryotes"},{"@id":"https://cir.nii.ac.jp/all?q=parasites","dc:title":"parasites"},{"@id":"https://cir.nii.ac.jp/all?q=Models,%20Biological","dc:title":"Models, Biological"},{"@id":"https://cir.nii.ac.jp/all?q=Trogocytosis","dc:title":"Trogocytosis"},{"@id":"https://cir.nii.ac.jp/all?q=Phagosomes","dc:title":"Phagosomes"},{"@id":"https://cir.nii.ac.jp/all?q=Animals","dc:title":"Animals"},{"@id":"https://cir.nii.ac.jp/all?q=cross-dressing","dc:title":"cross-dressing"},{"@id":"https://cir.nii.ac.jp/all?q=Parasites","dc:title":"Parasites"},{"@id":"https://cir.nii.ac.jp/all?q=trogocytosis","dc:title":"trogocytosis"},{"@id":"https://cir.nii.ac.jp/all?q=Cytology","dc:title":"Cytology"},{"@id":"https://cir.nii.ac.jp/all?q=%3Ci%3EEntamoeba%20histolytica%3C/i%3E","dc:title":"<i>Entamoeba histolytica</i>"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040000782014704384","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"19H03463"},{"@type":"JGN","@value":"JP19H03463"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H03463/"}],"notation":[{"@language":"ja","@value":"腸管寄生性原虫赤痢アメーバのホスファチジルイノシトールシグナルの解明"},{"@language":"en","@value":"Phoshatidylinositol signal in the enteric protozoan parasite Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1040285300696961792","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"20H05353"},{"@type":"JGN","@value":"JP20H05353"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-20H05353/"}],"notation":[{"@language":"ja","@value":"腸管寄生性原虫赤痢アメーバにおけるオートファジータンパク質の機能解明"},{"@language":"en","@value":"Functional analysis of autophagy proteins in enteric protozoan parasite Entamoeba histolytica"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050575520346423808","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360002219512548864","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Novel Transmembrane Receptor Involved in Phagosome Transport of Lysozymes and β-Hexosaminidase in the Enteric Protozoan Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004232204189312","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ligand heterogeneity of the cysteine protease binding protein family in the parasitic protist Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011143964702080","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Differences in morphology of phagosomes and kinetics of acidification and degradation in phagosomes between the pathogenicEntamoeba histolytica and the non-pathogenicEntamoeba dispar"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011145915826048","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Adherence and ingestion of Escherichia coli serotype 055 by trophozoites of Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011146418206464","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Self-Recognition in Social Amoebae Is Mediated by Allelic Pairs of\n                    <i>Tiger</i>\n                    Genes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013171506838272","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The parasite <i>Toxoplasma</i> sequesters diverse Rab host vesicles within an intravacuolar network"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013171739130368","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A predatory slime mould"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172310582144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Generation of Mechanical Forces in Phagocytosing Amoebae: Light and Electron Microscopic Study<sup>1</sup>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172392933120","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Developmentally programmed germ cell remodelling by endodermal cell cannibalism"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172514209408","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Species recognition in social amoebae"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172575439360","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Pinocytotic Uptake and the Digestion of Hemoglobin in Malaria Parasites*<sup>†</sup>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172702000384","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"PATHOGENIC <i>NAEGLERIA</i> AND <i>HARTMANNELLA (ACANTHAMOEBA)</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172797923840","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Activation of the Complement System in the Lower Genital Tract During Pregnancy and Delivery"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172872925056","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Trichomonas vaginalis: Pathogenesis, Symbiont Interactions, and Host Cell Immune Responses"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172969826944","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Sleeping Sickness: A Tale of Two Clocks"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013172998673024","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Communicative functions of GPI-anchored surface proteins in unicellular eukaryotes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013173035614592","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A Novel, Phospholipase C-independent Pathway of Inositol 1,4,5-Trisphosphate Formation in Dictyostelium and Rat Liver"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013173041728000","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013173251455616","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Structural Bases of the Cytolytic Mechanisms of Entamoeba histolytica<sup>1</sup>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017280671849472","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Proteomic analysis of Atg8-dependent recruitment of phagosomal proteins in the enteric protozoan parasite Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360283692109216640","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Fratricide of natural killer cells dressed with tumor-derived NKG2D ligand"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285708939801856","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Trogocytosis of peptide–MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285710473337728","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Atg8 is involved in endosomal and phagosomal acidification in the parasitic protist\n            <i>E</i>\n            <i>ntamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285710776850944","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Inositol 1,4,5‐trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist <i><scp>T</scp>rypanosoma cruzi</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292618681677824","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Biting Off What Can Be Chewed: Trogocytosis in Health, Infection, and Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619142237056","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Rat and human colonic mucins bind to and inhibit adherence lectin of Entamoeba histolytica."}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620075479936","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The parasite Entamoeba histolytica exploits the activities of human matrix metalloproteinases to invade colonic tissue"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620139470080","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"RHO GTPASES: Biochemistry and Biology"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294645354570112","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Neutrophils kill the parasite Trichomonas vaginalis using trogocytosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294646135875328","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Pathogenicity of Soil Amebas"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294646584704128","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Autophosphorylation at Thr279 of Entamoeba histolytica atypical kinase EhAK1 is required for activity and regulation of erythrophagocytosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294646591822464","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"<i>Giardia intestinalis</i> can interact, change its shape and internalize large particles and microorganisms"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294646625007360","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Trichomonas vaginalis: a review of epidemiologic, clinical and treatment issues"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294646747240192","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cellular landmarks of Trypanosoma brucei and Leishmania mexicana"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294646836065792","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"THE EXISTENCE OF A CYTOSTOME AND THE OCCURRENCE OF PINOCYTOSIS IN THE TRYPANOSOME, <i>TRYPANOSOMA MEGA </i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647054815360","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Evidence for two mechanisms of human erythrocyte endocytosis by Entamoeba histolytica‐like amoebae (Laredo strain)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647113242496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Form and Function of the Cytostome‐Cytopharynx of the Culture Forms of the Elasmobranch Haemoflagellate Trypanosoma raiae Laveran & Mesnil"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647308060928","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Phagocytic behavior of the predatory slime mold, Dictyostelium caveatum"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647345799296","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Between a bug and a hard place:<i>Trypanosoma cruzi</i>genetic diversity and the clinical outcomes of Chagas disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647454471168","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"On the Fine Structure of <i>Trypanosoma cruzi</i> in Tissue Cultures of Pigment Epithelium from the Chick Embryo. Uptake of Melanin Granules by the Parasite*"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647562779392","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Immunolocalization of Actin in <i>Paramecium</i> Cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647688228736","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A new model for hemoglobin ingestion and transport by the human malaria parasite <i>Plasmodium falciparum</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647708648832","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Emerging Mechanisms of Endocytosis in Toxoplasma gondii"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294647796229632","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The global cysteine peptidase landscape in parasites"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294648132259328","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Amino acid efflux by asexual blood-stage Plasmodium falciparum and its utility in interrogating the kinetics of hemoglobin endocytosis and catabolism in vivo"}]},{"@id":"https://cir.nii.ac.jp/crid/1360301162841605504","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Receptors for Phagocytosis and Trogocytosis in Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565167085026304","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Natural killer (NK)–dendritic cell interactions generate MHC class II-dressed NK cells that regulate CD4\n                    <sup>+</sup>\n                    T cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567183435065728","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Hetero-oligomer of dynamin-related proteins participates in the fission of highly divergent mitochondria from Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567185577366400","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A novel class of cysteine protease receptors that mediate lysosomal transport"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095238843264","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Toxoplasma gondii Sequesters Lysosomes from Mammalian Hosts in the Vacuolar Space"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095682892672","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Apoptotic Killing and Phagocytosis of Host Cells by the Parasite<i>Entamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576120135672960","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A Contiguous Compartment Functions as Endoplasmic Reticulum and Endosome/Lysosome in\n            <i>Giardia lamblia</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576121113227520","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Phagocytosis: Our Current Understanding of a Universal Biological Process"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576121489892480","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Discrimination Experiments in <i>Entamoeba</i> and Evidence from Other Protists Suggest Pathogenic Amebas Cooperate with Kin to Colonize Hosts and Deter Rivals"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576121521821184","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Observations on Ameba Feeding on Infusoria, and Their Bearing on the Surface-Tension Theory"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576121545591424","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Toxoplasma gondii Ingests and Digests Host Cytosolic Proteins"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576121844797568","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"An In Vitro Model of the Blood–Brain Barrier: <i>Naegleria fowleri</i> Affects the Tight Junction Proteins and Activates the Microvascular Endothelial Cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576121927925504","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Near-chromosome level genome assembly reveals ploidy diversity and plasticity in the intestinal protozoan parasite Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576122230285824","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The ancestry and cumulative evolution of immune reactions."}]},{"@id":"https://cir.nii.ac.jp/crid/1360576122556331904","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Trypanosomatid Flagellar Pocket from Structure to Function"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576122584474240","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Analysis of the protein kinome of <i>Entamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576122627305344","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endocytosis at the micropore ofToxoplasma gondii"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576122642920064","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Cytostome of Trypanosoma cruzi and T. conorhini*"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576122671172480","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Observations on Amoeba Feeding on The Ciliate Frontonia"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576123031131136","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Microbial Phagocytic Receptors and Their Potential Involvement in Cytokine Induction in Macrophages"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576123178348288","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"<i>Trypanosoma lucknowi</i>, a New Species of Trypanosome from <i>Macaca mulatta</i> with Observations on Its Fine Structure1"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576123181081728","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The release of glycosylphosphatidylinositol-anchored proteins from the cell surface"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576123201191040","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Acquisition of Host Cytosolic Protein by Toxoplasma gondii Bradyzoites"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576123233113472","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Phagocytosis by <i>Trichomonas vaginalis</i>: new insights"}]},{"@id":"https://cir.nii.ac.jp/crid/1360845539135142528","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Apoptotic cell recognition receptors and scavenger receptors"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848658395154432","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"AGC family kinase 1 participates in trogocytosis but not in phagocytosis in Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848660904428544","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cysteine Protease-Binding Protein Family 6 Mediates the Trafficking of Amylases to Phagosomes in the Enteric Protozoan Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569448822784","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Entamoeba histolytica. Phagocytosis as a virulence factor."}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569708114176","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Regulation of Adherence and Virulence by the<i>Entamoeba histolytica</i>Lectin Cytoplasmic Domain, Which Contains a β2 Integrin Motif"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569964126592","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"In Vivo Transfer of GPI-Linked Complement Restriction Factors from Erythrocytes to the Endothelium"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570461830016","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"<i>Trichomonas vaginalis</i>\n                    kills and eats – evidence for phagocytic activity as a cytopathic effect"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570780405888","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Toxoplasmosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857595028574592","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Brains and Brawn: Toxoplasma Infections of the Central Nervous System and Skeletal Muscle"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857595413571072","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Immune Response to<i>Giardia duodenalis</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857595788685696","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Inhibition of Amebic Cysteine Proteases Blocks Amebic Trogocytosis but Not Phagocytosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857596613836928","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Traffic to the Malaria Parasite Food Vacuole"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857596713822336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A mechanical perspective on phagocytic cup formation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857596867352704","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Membrane structure of Entamoeba histolytica: Fine structure of freeze-fractured membranes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857596929917696","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Resolvin D1 promotes the targeting and clearance of necroptotic cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857597045974528","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Phospholipase‐C‐Independent Inositol 1,4,5‐Trisphosphate Formation in <i>Dictyostelium</i> Cells — Activation of a Plasma‐Membrane‐Bound Phosphatase by Receptor‐Stimulated Ca<sup>2+</sup> Influx"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857597270598912","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Membrane Skeleton in Paramecium: Molecular Characterization of a Novel Epiplasmin Family and Preliminary GFP Expression Results"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857597396119552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"<i>Plasmodium falciparum</i> Atg18 localizes to the food vacuole via interaction with the multi-drug resistance protein 1 and phosphatidylinositol 3-phosphate"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857597496393600","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Evidence for a Bacterial Lipopolysaccharide-Recognizing G-Protein-Coupled Receptor in the Bacterial Engulfment by Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857597684343424","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857597836318848","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Breakdown of self/nonself recognition in cannibalistic strains of the predatory slime mold, Dictyostelium caveatum."}]},{"@id":"https://cir.nii.ac.jp/crid/1360857598090974720","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Loss of the cytostome-cytopharynx and endocytic ability are late events in Trypanosoma cruzi metacyclogenesis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857598120823552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"<i>Entamoeba</i> Clone‐Recognition Experiments: Morphometrics, Aggregative Behavior, and Cell‐Signaling Characterization"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857598208413184","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Complement-Mediated Regulation of <i>Trichomonas vaginalis</i> Infection in Mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044746565376","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The phagotrophic origin of eukaryotes and phylogenetic classification of Protozoa."}]},{"@id":"https://cir.nii.ac.jp/crid/1361137046450513536","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Binding and Internalization of Rat Colonic Mucins by the Galactose/N-Acetyl-n-Galactosamine Adherence Lectin of Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418519660524288","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Entamoeba histolytica and pathogenesis: A calcium connection"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418519921484928","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mechanics of membrane–cytoskeleton attachment in<i>Paramecium</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520140884608","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cytopathogenicity of entamoeba histolytica: The role of amebic adherence and contact-dependent cytolysis in pathogenesis"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520504325760","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Role of Adherence in Cytopathogenic Mechanisms of Entamoeba Histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520725283840","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The nuts and bolts of AGC protein kinases"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520809745920","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Elastolytic Proteases"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418521454251136","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Molecular and Biochemical Properties of a Cysteine Protease of Acanthamoeba castellanii"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993751082496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A contractile activity that closes phagosomes in macrophages"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993846778496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"THE FEEDING MECHANISM OF AVIAN MALARIAL PARASITES"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993866849920","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Trogocytosis by Entamoeba histolytica Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994711536256","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Digestive-vacuole genesis and endocytic processes in the early intraerythrocytic stages of<i>Plasmodium falciparum</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995206819840","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Malaria: Biology and Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995824007680","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape"}]},{"@id":"https://cir.nii.ac.jp/crid/1361975845333902208","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Two isotypes of phosphatidylinositol 3‐phosphate\n            <b>‐</b>\n            binding sorting nexins play distinct roles in trogocytosis in\n            <i>Entamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469107730560","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Predation and eukaryote cell origins: A coevolutionary perspective"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981470413726336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Actin dynamics and turnover in cell motility"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981470886106880","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Overexpression of cysteine proteinase 2 in Entamoeba histolytica or Entamoeba dispar increases amoeba-induced monolayer destruction in vitro but does not augment amoebic liver abscess formation in gerbils"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981471209050368","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Relative importance of inositol (1,4,5)trisphosphate and inositol (1,3,4,5)tetrakisphosphate in <i>Entamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262943769462400","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Trogocytosis by Entamoeba histolytica contributes to cell killing and tissue invasion"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944377335424","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Phosphatidylinositol-phosphates mediate cytoskeletal reorganization during phagocytosis via a unique modular protein consisting of RhoGEF/DH and FYVE domains in the parasitic protozoon<i>Entamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944914916864","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A C2 domain protein kinase initiates phagocytosis in the protozoan parasite Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262945070347776","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Proteomic analysis of Gal/GalNAc lectin-associated proteins in Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262945298989184","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A Retromerlike Complex Is a Novel Rab7 Effector That Is Involved in the Transport of the Virulence Factor Cysteine Protease in the Enteric Protozoan Parasite<i>Entamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262946419461504","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Calmodulin-like Calcium Binding Protein EhCaBP3 of Entamoeba histolytica Regulates Phagocytosis and Is Involved in Actin Dynamics"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544418465748352","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cells nibble one another via the under-appreciated process of trogocytosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544419381888384","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"<i>Toxoplasma gondii</i>\n                    salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544419989418496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Four distinct pathways of hemoglobin uptake in the malaria parasite\n                    <i>Plasmodium falciparum</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544420118831104","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Rab5-associated Vacuoles Play a Unique Role in Phagocytosis of the Enteric Protozoan Parasite Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544420414221056","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cysteine proteases of parasitic organisms"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893439456256","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"OBSERVATIONS BY IMMUNOFLUORESCENCE MICROSCOPY AND ELECTRON MICROSCOPY ON THE CYTOPATHOGENICITY OF NAEGLERIA FOWLERI IN MOUSE EMBRYO-CELL CULTURES"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893623703680","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Newly visualized fibrillar collagen scaffolds dictate Entamoeba histolytica invasion route in the human colon"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825896001622784","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Identification of Intracellular and Plasma Membrane Calcium Channel Homologues in Pathogenic Parasites"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369328756736","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Isolation of the galactose-binding lectin that mediates the in vitro adherence of Entamoeba histolytica."}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369919187328","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Tissue Destruction by Neutrophils"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107370067601280","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Antigen‐presenting cell exosomes are protected from complement‐mediated lysis by expression of CD55 and CD59"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107370091442560","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Structure and function of the Entamoeba histolytica Gal/GalNAc lectin"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388843223545216","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Identification of Entamoeba histolytica thiol-specific antioxidant as a GalNAc lectin-associated protein"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845055016832","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Entamoeba histolytica: Differences in phagosome acidification and degradation between attenuated and virulent strains"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845139221504","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Polymorphic Members of the lag Gene Family Mediate Kin Discrimination in Dictyostelium"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670318417639168","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The current status of zoonotic leishmaniases and approaches to disease control"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670319255535104","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Involvement of lectin pathway activation in the complement killing of Giardia intestinalis"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670319495415296","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The origins of phagocytosis and eukaryogenesis"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670320025354880","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Involvement of p21racA, phosphoinositide 3-kinase, and vacuolar ATPase in phagocytosis of bacteria and erythrocytes by Entamoeba histolytica: suggestive evidence for coincidental evolution of amebic invasiveness"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951794058826752","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"EhRho1 regulates plasma membrane blebbing through PI3 kinase in<i>Entamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951795422389760","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Malarial hemozoin: From target to tool"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951795638418688","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"EhRho1 regulates phagocytosis by modulating actin dynamics through EhFormin1 and EhProfilin1 in<i>Entamoeba histolytica</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233268620464512","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cutaneous leishmaniasis"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269555910144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Fine Structure of Human Malaria <i>In Vitro</i>*†"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270885666432","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Sequestration of host-CD59 as potential immune evasion strategy of Trichomonas vaginalis"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233271196628992","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Myo-inositol trisphosphate-mediated calcium release from internal stores of Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1370576118740094080","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Cell Surface of Trypanosoma cruzi: A Fracture-Flip, Replica-Staining Label-Fracture Survey"}]},{"@id":"https://cir.nii.ac.jp/crid/1370576118740094096","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ultrastructural and Immunohistochemical Studies on Trichomonas vaginalis Adhering to and Phagocytizing Genitourinary Epithelial Cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1370576118740094105","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ultrastructure of Plasmodium falciparum “in Vitro”. I. Base-Line for Drug Effects Evaluation"}]},{"@id":"https://cir.nii.ac.jp/crid/1370576118740094214","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Amoebic Dysentery"}]},{"@id":"https://cir.nii.ac.jp/crid/1370582635653680257","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"From Darwin and Metchnikoff to Burnet and Beyond"}]},{"@id":"https://cir.nii.ac.jp/crid/1370582635653680512","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Leishmaniasis: A Review"}]},{"@id":"https://cir.nii.ac.jp/crid/1370582635653680768","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Polymorphic Proteins TgrB1 and TgrC1 Function as a Ligand-Receptor Pair in Dictyostelium Allorecognition"}]},{"@id":"https://cir.nii.ac.jp/crid/1370582635653680769","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Rab7D Small GTPase Is Involved in Phago-, Trogocytosis and Cytoskeletal Reorganization in the Enteric Protozoan Entamoeba histolytica"}]},{"@id":"https://cir.nii.ac.jp/crid/1370582635653680771","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Small GTP-Binding Protein RacG Regulates Uroid Formation in the Protozoan Parasite Entamoeba histolytica"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.3390/cells10112975"},{"@type":"KAKEN","@value":"PRODUCT-23808379"},{"@type":"KAKEN","@value":"PRODUCT-23864262"},{"@type":"OPENAIRE","@value":"doi_dedup___::16a6e176f2c173b502b197f5eefacf3d"},{"@type":"CROSSREF","@value":"10.3389/fcimb.2022.961645_references_DOI_V9ffkFXgohOdjokpOG5u0BwCKkk"}]}