{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360576118802401152.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3389/fcvm.2021.631807"}},{"identifier":{"@type":"URI","@value":"https://www.frontiersin.org/articles/10.3389/fcvm.2021.631807/full"}},{"identifier":{"@type":"PMID","@value":"33869301"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Cardio-Ankle Vascular Index Reflects Impaired Exercise Capacity and Predicts Adverse Prognosis in Patients With Heart Failure"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p><jats:bold>Aims:</jats:bold> We aimed to assess the associations of CAVI with exercise capacity in heart failure (HF) patients. In addition, we further examined their prognosis.</jats:p><jats:p><jats:bold>Methods:</jats:bold> We collected the clinical data of 223 patients who had been hospitalized for decompensated HF and had undergone both CAVI and cardiopulmonary exercise testing.</jats:p><jats:p><jats:bold>Results:</jats:bold> For the prediction of an impaired peak oxygen uptake (VO<jats:sub>2</jats:sub>) of &lt; 14 mL/kg/min, receiver-operating characteristic curve demonstrated that the cutoff value of CAVI was 8.9. In the multivariate logistic regression analysis for predicting impaired peak VO<jats:sub>2</jats:sub>, high CAVI was found to be an independent factor (odds ratio 2.343, <jats:italic>P</jats:italic> = 0.045). We divided these patients based on CAVI: the low-CAVI group (CAVI &lt; 8.9, <jats:italic>n</jats:italic> = 145) and the high-CAVI group (CAVI ≥ 8.9, <jats:italic>n</jats:italic> = 78). Patient characteristics and post-discharge cardiac events were compared between the two groups. The high-CAVI group was older (69.0 vs. 58.0 years old, <jats:italic>P</jats:italic> &lt; 0.001) and had lower body mass index (23.0 vs. 24.1 kg/m<jats:sup>2</jats:sup>, <jats:italic>P</jats:italic> = 0.013). During the post-discharge follow-up period of median 1,623 days, 58 cardiac events occurred. The Kaplan–Meier analysis demonstrated that the cardiac event rate was higher in the high-CAVI group than in the low-CAVI group (log–rank <jats:italic>P</jats:italic> = 0.004). The multivariate Cox proportional hazard analysis revealed that high CAVI was an independent predictor of cardiac events (hazard ratio 1.845, <jats:italic>P</jats:italic> = 0.035).</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> High CAVI is independently associated with impaired exercise capacity and a high cardiac event rate in HF patients.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380576118802401168","@type":"Researcher","foaf:name":[{"@value":"Koichiro Watanabe"}]},{"@id":"https://cir.nii.ac.jp/crid/1420282801197320448","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"40448642"},{"@type":"NRID","@value":"1000040448642"},{"@type":"NRID","@value":"9000412546234"},{"@type":"NRID","@value":"9000014116060"},{"@type":"NRID","@value":"9000004290831"},{"@type":"NRID","@value":"9000243898304"},{"@type":"NRID","@value":"9000403401352"},{"@type":"NRID","@value":"9000399362083"},{"@type":"NRID","@value":"9000003869698"},{"@type":"NRID","@value":"9000345256156"},{"@type":"NRID","@value":"9000243877647"},{"@type":"NRID","@value":"9000243882139"},{"@type":"NRID","@value":"9000402897693"},{"@type":"NRID","@value":"9000403405001"},{"@type":"NRID","@value":"9000398260203"},{"@type":"NRID","@value":"9000021656039"},{"@type":"NRID","@value":"9000410737750"},{"@type":"NRID","@value":"9000403424715"},{"@type":"NRID","@value":"9000402240610"},{"@type":"NRID","@value":"9000402247070"},{"@type":"NRID","@value":"9000406283047"},{"@type":"NRID","@value":"9000382669415"},{"@type":"NRID","@value":"9000240055920"},{"@type":"NRID","@value":"9000414812911"},{"@type":"NRID","@value":"9000403988989"},{"@type":"NRID","@value":"9000405664048"},{"@type":"NRID","@value":"9000318139170"},{"@type":"NRID","@value":"9000362823603"},{"@type":"NRID","@value":"9000412034028"},{"@type":"NRID","@value":"9000258743200"},{"@type":"NRID","@value":"9000350623291"},{"@type":"NRID","@value":"9000283595403"},{"@type":"NRID","@value":"9000316692705"},{"@type":"NRID","@value":"9000411211990"},{"@type":"NRID","@value":"9000413357763"},{"@type":"NRID","@value":"9000399218820"},{"@type":"NRID","@value":"9000404510496"},{"@type":"NRID","@value":"9000014667083"},{"@type":"NRID","@value":"9000019985120"},{"@type":"NRID","@value":"9000022017384"},{"@type":"NRID","@value":"9000362231107"},{"@type":"NRID","@value":"9000415052034"},{"@type":"NRID","@value":"9000397684454"},{"@type":"NRID","@value":"9000283225902"},{"@type":"NRID","@value":"9000022025760"},{"@type":"NRID","@value":"9000368940247"},{"@type":"NRID","@value":"9000240094236"},{"@type":"NRID","@value":"9000398612232"},{"@type":"NRID","@value":"9000283595069"},{"@type":"NRID","@value":"9000020605726"},{"@type":"NRID","@value":"9000391376235"},{"@type":"NRID","@value":"9000240094112"},{"@type":"NRID","@value":"9000397951705"},{"@type":"NRID","@value":"9000287355322"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0143634"}],"foaf:name":[{"@value":"Akiomi Yoshihisa"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401174","@type":"Researcher","foaf:name":[{"@value":"Yu Sato"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401156","@type":"Researcher","foaf:name":[{"@value":"Yu Hotsuki"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401286","@type":"Researcher","foaf:name":[{"@value":"Fumiya Anzai"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401176","@type":"Researcher","foaf:name":[{"@value":"Yasuhiro Ichijo"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401281","@type":"Researcher","foaf:name":[{"@value":"Yusuke Kimishima"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401153","@type":"Researcher","foaf:name":[{"@value":"Tetsuro Yokokawa"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401177","@type":"Researcher","foaf:name":[{"@value":"Tomofumi Misaka"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401029","@type":"Researcher","foaf:name":[{"@value":"Takamasa Sato"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401282","@type":"Researcher","foaf:name":[{"@value":"Takashi Kaneshiro"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401166","@type":"Researcher","foaf:name":[{"@value":"Masayoshi Oikawa"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401154","@type":"Researcher","foaf:name":[{"@value":"Atsushi Kobayashi"}]},{"@id":"https://cir.nii.ac.jp/crid/1380576118802401179","@type":"Researcher","foaf:name":[{"@value":"Yasuchika Takeishi"}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"2297055X"}],"prism:publicationName":[{"@value":"Frontiers in Cardiovascular Medicine"}],"dc:publisher":[{"@value":"Frontiers Media SA"}],"prism:publicationDate":"2021-03-29","prism:volume":"8"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","dc:rights":["https://creativecommons.org/licenses/by/4.0/"],"url":[{"@id":"https://www.frontiersin.org/articles/10.3389/fcvm.2021.631807/full"}],"createdAt":"2021-03-29","modifiedAt":"2021-03-29","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=arterial%20stiffness","dc:title":"arterial stiffness"},{"@id":"https://cir.nii.ac.jp/all?q=cardio-ankle%20vascular%20index","dc:title":"cardio-ankle vascular index"},{"@id":"https://cir.nii.ac.jp/all?q=RC666-701","dc:title":"RC666-701"},{"@id":"https://cir.nii.ac.jp/all?q=cardiopulmonary%20exercise%20testing","dc:title":"cardiopulmonary exercise testing"},{"@id":"https://cir.nii.ac.jp/all?q=heart%20failure","dc:title":"heart failure"},{"@id":"https://cir.nii.ac.jp/all?q=Diseases%20of%20the%20circulatory%20(Cardiovascular)%20system","dc:title":"Diseases of the circulatory (Cardiovascular) 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Peripheral Artery Disease on Prognosis in Hospitalized Heart Failure Patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679408898432","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Cardio-Ankle Vascular Index (CAVI) as a Novel Indicator of Arterial Stiffness: Theory, Evidence and Perspectives"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680081785600","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Elevated Arterial Stiffness Evaluated by Brachial-Ankle Pulse Wave Velocity is Deleterious for the Prognosis of Patients With Heart Failure"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680083595904","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Clinical Impact of the Cardio-Ankle Vascular Index for Predicting Cardiovascular Events After Acute Coronary Syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680085490048","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Prognostic Significance of Insomnia in Heart Failure"}]},{"@id":"https://cir.nii.ac.jp/crid/1390285300179298048","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Physical Function and Cardio-Ankle Vascular Index in Elderly Heart Failure Patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1390564227306263808","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure　― Digest Version ―"},{"@value":"JCS GUIDELINES : JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure : Digest Version"},{"@value":"Japanese Circulation Society and the Japanese Heart Failure Society Joint Working Group. JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure- Digest Version"},{"@value":"JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure—Digest Version"},{"@value":"JCS 2017/JHFS 2017 Guideline on diagnosis and treatment of acute and chronic heart failure — digest version —"},{"@value":"JCS 2017/JHFS 2017 guideline on diagnosis and treatment of acute and chronic heart failure"},{"@value":"JCS 2017/JHFS 2017 guideline on diagnosis and treatment of acute and chronic heart failure- digest version. JCS 2017/JHFS 2017 guideline on diagnosis and treatment of acute and chronic heart failure- digest version"},{"@value":"Japanese Circulation Society and the Japanese Heart Failure Society Joint Working Group. JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure—Digest Version"},{"@value":"Japanese Circulation Society and the Japanese Heart Failure Society Joint Working Group. Guidelines for diagnosis and treatment of acute and chronic heart failure"}]},{"@id":"https://cir.nii.ac.jp/crid/1390583159490843904","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Short Physical Performance Battery and Cardio-Ankle Vascular Index Association in Older Patients with Heart Failure"}]},{"@id":"https://cir.nii.ac.jp/crid/1870302167842033408","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Prognostic factors in heart failure patients with cardiac cachexia."}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.3389/fcvm.2021.631807"},{"@type":"KAKEN","@value":"PRODUCT-23997938"},{"@type":"OPENAIRE","@value":"doi_dedup___::b047993aa2bc2ef56397757cd03d1010"},{"@type":"CROSSREF","@value":"10.1536/ihj.24-378_references_DOI_XnNTZzmanv2wV0F5B4so88kBA9v"}]}