Structure of human Vitronectin C-terminal domain and interaction with <i>Yersinia pestis</i> outer membrane protein Ail

  • Kyungsoo Shin
    Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Bernhard C. Lechtenberg
    Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Lynn M. Fujimoto
    Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Yong Yao
    Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Sara Schesser Bartra
    Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.
  • Gregory V. Plano
    Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.
  • Francesca M. Marassi
    Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

Description

<jats:p>The blood protein Vitronectin forms a four-bladed propeller that is a hub for multiple functions and binds pathogenic bacteria.</jats:p>

Journal

  • Science Advances

    Science Advances 5 (9), eaax5068-, 2019-09-06

    American Association for the Advancement of Science (AAAS)

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