{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360579820399865088.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1021/jacsau.2c00117"}},{"identifier":{"@type":"URI","@value":"https://pubs.acs.org/doi/pdf/10.1021/jacsau.2c00117"}},{"identifier":{"@type":"DOI","@value":"10.26434/chemrxiv-2021-p71pl-v2"}},{"identifier":{"@type":"URI","@value":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/61a70cc77848051383a0ffbb/original/pattern-recognition-of-micro-rna-expression-in-body-fluids-using-nanopore-decoding-at-sub-femtomolar-concentration.pdf"}},{"identifier":{"@type":"DOI","@value":"10.26434/chemrxiv-2021-p71pl"}},{"identifier":{"@type":"PMID","@value":"36032536"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Pattern Recognition of microRNA Expression in Body Fluids Using Nanopore Decoding at Subfemtomolar Concentrations"}],"description":[{"notation":[{"@value":"<jats:p>This paper describes nanopore decoding for microRNA (miRNA) expression patterns using DNA computing technology. miRNAs have shown promise as markers for cancer diagnosis due to their cancer type-specificity, and therefore simple strategies for miRNA-pattern recognition are required. We propose a system for pattern recognition of five types of miRNAs overexpressed in bile duct cancer (BDC). The information of miRNAs from BDC is encoded in diagnostic DNAs (dgDNAs) and decoded electrically by nanopore measurement. With this system, we succeeded in distinguishing miRNA expression patterns in the plasma of BDC patients using a label-free method and in real-time. Moreover, our dgDNA-miRNAs complexes can be captured by the nanopore at ultralow concentration, such as 0.1 fM. Such nanopore decoding with dgDNAs could be applied as a simple and early diagnostic tool for cancer in the future.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380579820399865090","@type":"Researcher","foaf:name":[{"@value":"Nanami Takeuchi"}],"jpcoar:affiliationName":[{"@value":"Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820399865088","@type":"Researcher","foaf:name":[{"@value":"Moe Hiratani"}],"jpcoar:affiliationName":[{"@value":"Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1420001326237159552","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"90401702"},{"@type":"NRID","@value":"1000090401702"},{"@type":"NRID","@value":"9000018747694"},{"@type":"NRID","@value":"9000238280358"},{"@type":"NRID","@value":"9000278462703"},{"@type":"NRID","@value":"9000303638319"},{"@type":"NRID","@value":"9000323295278"},{"@type":"NRID","@value":"9000392782962"},{"@type":"NRID","@value":"9000356891134"},{"@type":"NRID","@value":"9000024950563"},{"@type":"NRID","@value":"9000303640488"},{"@type":"NRID","@value":"9000277501578"},{"@type":"NRID","@value":"9000380968615"},{"@type":"NRID","@value":"9000411621224"},{"@type":"NRID","@value":"9000258576509"},{"@type":"NRID","@value":"9000313624413"},{"@type":"NRID","@value":"9000404629373"},{"@type":"NRID","@value":"9000329433630"},{"@type":"NRID","@value":"9000309159917"},{"@type":"NRID","@value":"9000386208428"},{"@type":"NRID","@value":"9000390889281"},{"@type":"NRID","@value":"9000286623122"},{"@type":"NRID","@value":"9000356656732"},{"@type":"NRID","@value":"9000017715086"},{"@type":"NRID","@value":"9000238282876"},{"@type":"NRID","@value":"9000313199064"},{"@type":"NRID","@value":"9000253358225"},{"@type":"NRID","@value":"9000402476847"},{"@type":"NRID","@value":"9000238282975"},{"@type":"NRID","@value":"9000000753167"},{"@type":"NRID","@value":"9000238282901"},{"@type":"NRID","@value":"9000303641952"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/rjkawano"}],"foaf:name":[{"@value":"Ryuji Kawano"}],"jpcoar:affiliationName":[{"@value":"Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"26913704"},{"@type":"EISSN","@value":"26913704"}],"prism:publicationName":[{"@value":"JACS Au"}],"dc:publisher":[{"@value":"American Chemical Society (ACS)"}],"prism:publicationDate":"2022-06-26","prism:volume":"2","prism:number":"8","prism:startingPage":"1829","prism:endingPage":"1838"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","dc:rights":["https://creativecommons.org/licenses/by-nc-nd/4.0/"],"url":[{"@id":"https://pubs.acs.org/doi/pdf/10.1021/jacsau.2c00117"},{"@id":"https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/61a70cc77848051383a0ffbb/original/pattern-recognition-of-micro-rna-expression-in-body-fluids-using-nanopore-decoding-at-sub-femtomolar-concentration.pdf"}],"createdAt":"2022-06-26","modifiedAt":"2023-04-27","project":[{"@id":"https://cir.nii.ac.jp/crid/1040282256990286976","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"19H00901"},{"@type":"JGN","@value":"JP19H00901"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H00901/"}],"notation":[{"@language":"ja","@value":"分子演算システムによる腫瘍由来核酸の高速パターン診断"},{"@language":"en","@value":"Rapid pattern recognition of OncomiR by DNA computation"}]},{"@id":"https://cir.nii.ac.jp/crid/1040577354308451456","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"22KJ1231"},{"@type":"JGN","@value":"JP22KJ1231"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22KJ1231/"}],"notation":[{"@language":"ja","@value":"ナノポア計測とDNAコンピューティング技術による超低濃度microRNAの検出"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360004233118495616","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Amplification and Quantification of an Antisense Oligonucleotide from Target microRNA Using Programmable DNA and a Biological Nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142475506944","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Analytical Model for Particle Capture in Nanopores Elucidates Competition among Electrophoresis, Electroosmosis, and Dielectrophoresis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011144252687872","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013168776503936","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Recognition of Single‐Point Mutation Using a Biological Nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017282189066880","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Cell-Free Expression of <i>De Novo</i> Designed Peptides That Form β-Barrel Nanopores"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017284661779840","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cellular microRNA detection with miRacles: microRNA- activated conditional looping of engineered switches"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017285493987456","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Probing molecular pathways for DNA orientational trapping, unzipping and translocation in nanopores by using a tunable overhang sensor"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017287199493120","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cancer diagnosis with DNA molecular computation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017288451894272","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Logic devices based on nucleic acid self‐assembly"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017288452171520","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"MicroRNA-155 complementation on a chemically functionalized dual electrode surface for determining breast cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017288452946304","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Current Simultaneous Discrimination of Mismatched MicroRNAs Using Base-Flipping within the α-Hemolysin Latch"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017288454004224","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A new method for early detection of pancreatic cancer biomarkers: detection of microRNAs by nanochannels"}]},{"@id":"https://cir.nii.ac.jp/crid/1360021390742461184","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Simultaneous Recognition of Over- and Under-Expressed MicroRNAs Using Nanopore Decoding"}]},{"@id":"https://cir.nii.ac.jp/crid/1360025429442224000","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Electrophysiological Evaluation for Gel-Supported Giant Unilamellar Vesicles"}]},{"@id":"https://cir.nii.ac.jp/crid/1360283691580504832","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Analysis of Pore Formation and Protein Translocation Using Large Biological Nanopores"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294648137723648","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nanopore decoding for a Hamiltonian path problem"}]},{"@id":"https://cir.nii.ac.jp/crid/1360298341516107648","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Plasmoelectronic-Based Ultrasensitive Assay of Tumor Suppressor microRNAs Directly in Patient Plasma: Design of Highly Specific Early Cancer Diagnostic Technology"}]},{"@id":"https://cir.nii.ac.jp/crid/1360298345427386496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Bottom-up fabrication of a proteasome–nanopore that unravels and processes single proteins"}]},{"@id":"https://cir.nii.ac.jp/crid/1360298761983801856","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Propelling DNA Computing with Materials’ Power: Recent Advancements in Innovative DNA Logic Computing Systems and Smart Bio‐Applications"}]},{"@id":"https://cir.nii.ac.jp/crid/1360302866834267648","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Nanopore Filter: A Method for Counting and Extracting Single DNA Molecules Using a Biological Nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1360306905609507968","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Harnessing DNA computing and nanopore decoding for practical applications: from informatics to microRNA-targeting diagnostics"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565169868324096","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A combination of circulating miRNAs for the early detection of ovarian cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567183109110144","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nanopore Logic Operation with DNA to RNA Transcription in a Droplet System"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567183572648960","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"MicroRNA detection at femtomolar concentrations with isothermal amplification and a biological nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567187540225536","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Logic Gate Operation by DNA Translocation through Biological Nanopores"}]},{"@id":"https://cir.nii.ac.jp/crid/1360568464482808704","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nanopore Decoding of Oligonucleotides in DNA Computing"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574093615679744","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094003645952","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Molecular Computation of Solutions to Combinatorial Problems"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576118716045824","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"De novo design of a nanopore for single-molecule detection that incorporates a β-hairpin peptide"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576120579961344","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580235943940224","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nanopore sensing: A physical-chemical approach"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580236819943936","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Revisiting the Origin of Nanopore Current Blockage for Volume Difference Sensing at the Atomic Level"}]},{"@id":"https://cir.nii.ac.jp/crid/1360584340510114944","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Lipid vesicle-based molecular robots"}]},{"@id":"https://cir.nii.ac.jp/crid/1360853567830680576","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569743161728","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570227262464","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"γ-Hemolysin Nanopore Is Sensitive to Guanine-to-Inosine Substitutions in Double-Stranded DNA at the Single-Molecule Level"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857593706628480","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Single polypeptide detection using a translocon EXP2 nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861710164947328","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A bifunctional DNA probe for sensing pH and microRNA using a nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861710913363200","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Programmable nano-reactors for stochastic sensing"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861711985776768","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861712703276032","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Lateral flow test for visual detection of multiple MicroRNAs"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861713215129472","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Capture and analysis of double‐stranded DNA with the α‐hemolysin nanopore: Fundamentals and applications"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861713216446336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Displacement chemistry-based nanopore analysis of nucleic acids in complicated matrices"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861714815053440","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Gold Nanoflares with Computing Function as Smart Diagnostic Automata for Multi-miRNA Patterns in Living Cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861714815340416","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A DNA logic gate based on strand displacement reaction and rolling circle amplification, responding to multiple low-abundance DNA fragment input signals, and its application in detecting miRNAs"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137046470357504","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Correction to Spatially Resolved Chemical Detection with a Nanoneedle-Probe-Supported Biological Nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1361412892866314624","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"DNA Logic Operation with Nanopore Decoding To Recognize MicroRNA Patterns in Small Cell Lung Cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995959858816","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nanopore-Based Selective Discrimination of MicroRNAs with Single-Nucleotide Difference Using Locked Nucleic Acid-Modified Probes"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699996080683264","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Programmable and autonomous computing machine made of biomolecules"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544420971411840","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Biomolecular computing systems: principles, progress and potential"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825894355775744","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"An autonomous molecular computer for logical control of gene expression"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825896020385024","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ionic Current Blockades from DNA and RNA Molecules in the α-Hemolysin Nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107368769405824","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nanopore-based detection of circulating microRNAs in lung cancer patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388843347639168","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Programming Nanopore Ion Flow for Encoded Multiplex MicroRNA Detection"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670318763630336","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Salt Gradient Modulation of MicroRNA Translocation through a Biological Nanopore"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670319969479936","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Circulating MicroRNAs in Cancer: Potential and Challenge"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951793686581120","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Alpha-Hederin Nanopore for Single Nucleotide Discrimination"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951795541453184","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Relaxing the Rule of Ten Events per Variable in Logistic and Cox Regression"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233268954657280","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"DNA nanotechnology assisted nanopore-based analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270222236288","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nanopore Unzipping of Individual DNA Hairpin Molecules"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681476324608","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Hairpin DNA Unzipping Analysis Using a Biological Nanopore Array"}]},{"@id":"https://cir.nii.ac.jp/crid/1390576811711412992","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Accelerating biophysical studies and applications by label-free nanopore sensing"}]},{"@id":"https://cir.nii.ac.jp/crid/1881429166466524800","@type":"Dataset","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Salt gradient modulation of microRNA translocation through a biological nanopore"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1021/jacsau.2c00117"},{"@type":"CROSSREF","@value":"10.26434/chemrxiv-2021-p71pl-v2"},{"@type":"KAKEN","@value":"PRODUCT-24493881"},{"@type":"KAKEN","@value":"PRODUCT-24382995"},{"@type":"OPENAIRE","@value":"doi_dedup___::754299b95d3994be86618013a6e69d45"},{"@type":"CROSSREF","@value":"10.1021/acsnano.2c07970_references_DOI_NrcQZjGCuy5hRvT97QjgPdTFPFB"},{"@type":"CROSSREF","@value":"10.1021/acs.analchem.3c02560_references_DOI_NrcQZjGCuy5hRvT97QjgPdTFPFB"},{"@type":"CROSSREF","@value":"10.1109/bmeicon64021.2024.10896372_references_DOI_NrcQZjGCuy5hRvT97QjgPdTFPFB"},{"@type":"CROSSREF","@value":"10.1021/acs.analchem.3c00573_references_DOI_NrcQZjGCuy5hRvT97QjgPdTFPFB"},{"@type":"CROSSREF","@value":"10.1021/jacsau.2c00117_hasPreprint_DOI_FtuHtmKTGH97dCChJ3fWGcMFnKa"},{"@type":"CROSSREF","@value":"10.1039/d3cs00396e_references_DOI_NrcQZjGCuy5hRvT97QjgPdTFPFB"},{"@type":"CROSSREF","@value":"10.1039/d3lc00860f_references_DOI_NrcQZjGCuy5hRvT97QjgPdTFPFB"},{"@type":"CROSSREF","@value":"10.26434/chemrxiv-2021-p71pl-v2_isPreprintOf_DOI_NrcQZjGCuy5hRvT97QjgPdTFPFB"},{"@type":"CROSSREF","@value":"10.2142/biophysico.bppb-v20.0010_references_DOI_NrcQZjGCuy5hRvT97QjgPdTFPFB"}]}