{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360579820494897024.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1177/17474930221138014"}},{"identifier":{"@type":"URI","@value":"https://journals.sagepub.com/doi/pdf/10.1177/17474930221138014"}},{"identifier":{"@type":"URI","@value":"https://journals.sagepub.com/doi/full-xml/10.1177/17474930221138014"}},{"identifier":{"@type":"PMID","@value":"36305084"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Primary results of mechanical thrombectomy for acute ischemic stroke: The K-NET registry in the Japanese metropolitan area"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:sec><jats:title>Background:</jats:title><jats:p> Endovascular treatment (EVT) for acute large vessel occlusion has proven to be effective in randomized controlled trials. We conducted a prospective cohort study to evaluate the real-world efficacy of EVT in a metropolitan area with a large number of comprehensive stroke centers and to compare it with the results of other registries and randomized controlled trials (RCTs). </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> We analyzed the Kanagawa Intravenous and Endovascular Treatment of Acute Ischemic Stroke registry, a prospective, multicenter observational study of patients treated by EVT and/or intravenous tissue-type plasminogen activator (tPA). Of the 2488 patients enrolled from January 2018 to June 2020, 1764 patients treated with EVT were included. The primary outcome was a good outcome, which was defined as a modified Rankin Scale (mRS) of 0–2 at 90 days. Secondary analysis included predicting a good outcome using multivariate logistic regression analysis. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> The median age was 77 years, and the median National Institute of Health Stroke Scale (NIHSS) score was 18. Pretreatment mRS score 0–2 was 87%, and direct transport was 92%. The rate of occlusion in anterior circulation was 90.3%. Successful recanalization was observed in 88.7%. The median time from onset to recanalization was 193 min. Good outcomes at 90 days were 43.3% in anterior circulation and 41.9% in posterior circulation. Overall mortality was 12.6%. Significant predictors for a good outcome were as follows: age, male, direct transfer, NIHSS score, Alberta Stroke Program Early Computed Tomography Score, intravenous tPA, and successful recanalization. </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> EVT in routine clinical use in a metropolitan area showed comparable good outcomes and lower mortality compared to previous studies, despite the high proportion of patients with older age, pretreatment mRS score of >2, posterior circulation occlusion, and higher NIHSS. Those results may have been associated with more direct transport and faster onset-to-recanalization times. </jats:p></jats:sec>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380579820494897033","@type":"Researcher","foaf:name":[{"@value":"Toshihiro Ueda"}],"jpcoar:affiliationName":[{"@value":"Department of Strokology and Neuroendovascular Therapy, Stroke Center, St. Marianna University Toyoko Hospital, Kawasaki, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897032","@type":"Researcher","foaf:name":[{"@value":"Yasuhiro Hasegawa"}],"jpcoar:affiliationName":[{"@value":"St. Marianna University School of Medicine, Kawasaki, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897041","@type":"Researcher","foaf:name":[{"@value":"Masataka Takeuchi"}],"jpcoar:affiliationName":[{"@value":"Seisho Hospital, Odawara, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897025","@type":"Researcher","foaf:name":[{"@value":"Masafumi Morimoto"}],"jpcoar:affiliationName":[{"@value":"Yokohama Shintoshi Neurosurgical Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897027","@type":"Researcher","foaf:name":[{"@value":"Yoshifumi Tsuboi"}],"jpcoar:affiliationName":[{"@value":"Kawasaki Saiwai Hospital, Kawasaki, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897045","@type":"Researcher","foaf:name":[{"@value":"Ryoo Yamamoto"}],"jpcoar:affiliationName":[{"@value":"Yokohama Brain and Spine Center, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897024","@type":"Researcher","foaf:name":[{"@value":"Shogo Kaku"}],"jpcoar:affiliationName":[{"@value":"Neurosurgical East Yokohama Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897044","@type":"Researcher","foaf:name":[{"@value":"Junichi Ayabe"}],"jpcoar:affiliationName":[{"@value":"Yokosuka Kyosai Hospital, Yokosuka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897038","@type":"Researcher","foaf:name":[{"@value":"Takekazu Akiyama"}],"jpcoar:affiliationName":[{"@value":"Akiyama Neurosurgical Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897029","@type":"Researcher","foaf:name":[{"@value":"Daisuke Ishima"}],"jpcoar:affiliationName":[{"@value":"Kitasato University Hospital, Sagamihara, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897026","@type":"Researcher","foaf:name":[{"@value":"Kentaro Mori"}],"jpcoar:affiliationName":[{"@value":"Yokohama Sakae Kyosai Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897047","@type":"Researcher","foaf:name":[{"@value":"Hiroshi Kagami"}],"jpcoar:affiliationName":[{"@value":"Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897031","@type":"Researcher","foaf:name":[{"@value":"Hidemichi Ito"}],"jpcoar:affiliationName":[{"@value":"St. Marianna University School of Medicine, Kawasaki, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897043","@type":"Researcher","foaf:name":[{"@value":"Hidetaka Onodera"}],"jpcoar:affiliationName":[{"@value":"St. Marianna University Yokohama Seibu Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897037","@type":"Researcher","foaf:name":[{"@value":"Hiroshi Doi"}],"jpcoar:affiliationName":[{"@value":"Yokohama City University Graduate School of Medicine, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897028","@type":"Researcher","foaf:name":[{"@value":"Tomoyuki Tsumoto"}],"jpcoar:affiliationName":[{"@value":"Showa University Fujigaoka Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897036","@type":"Researcher","foaf:name":[{"@value":"Shunsuke Hataoka"}],"jpcoar:affiliationName":[{"@value":"National Hospital Organization, Yokohama Medical Center, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897039","@type":"Researcher","foaf:name":[{"@value":"Masayuki Noda"}],"jpcoar:affiliationName":[{"@value":"Yokohama Shinmidori General Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897034","@type":"Researcher","foaf:name":[{"@value":"Nagatsuki Tomura"}],"jpcoar:affiliationName":[{"@value":"Yokohama Rosai Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897040","@type":"Researcher","foaf:name":[{"@value":"Osamu Masuo"}],"jpcoar:affiliationName":[{"@value":"Yokohama Municipal Citizen’s Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897042","@type":"Researcher","foaf:name":[{"@value":"Yoichi Yoshida"}],"jpcoar:affiliationName":[{"@value":"Yokohama Asahi Chuo General Hospital, Yokohama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897046","@type":"Researcher","foaf:name":[{"@value":"Yasuyuki Kaga"}],"jpcoar:affiliationName":[{"@value":"St. Marianna University School of Medicine, Kawasaki, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897035","@type":"Researcher","foaf:name":[{"@value":"Kentaro Tatsuno"}],"jpcoar:affiliationName":[{"@value":"Department of Strokology and Neuroendovascular Therapy, Stroke Center, St. Marianna University Toyoko Hospital, Kawasaki, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897153","@type":"Researcher","foaf:name":[{"@value":"Tomohide Yoshie"}],"jpcoar:affiliationName":[{"@value":"Department of Strokology and Neuroendovascular Therapy, Stroke Center, St. Marianna University Toyoko Hospital, Kawasaki, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897152","@type":"Researcher","foaf:name":[{"@value":"Satoshi Takaishi"}],"jpcoar:affiliationName":[{"@value":"Department of Strokology and Neuroendovascular Therapy, Stroke Center, St. Marianna University Toyoko Hospital, Kawasaki, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579820494897030","@type":"Researcher","foaf:name":[{"@value":"Yoshihisa Yamano"}],"jpcoar:affiliationName":[{"@value":"St. Marianna University School of Medicine, Kawasaki, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"17474930"},{"@type":"EISSN","@value":"17474949"}],"prism:publicationName":[{"@value":"International Journal of Stroke"}],"dc:publisher":[{"@value":"SAGE Publications"}],"prism:publicationDate":"2022-11-25","prism:volume":"18","prism:number":"5","prism:startingPage":"607","prism:endingPage":"614"},"reviewed":"false","dc:rights":["https://creativecommons.org/licenses/by-nc/4.0/"],"url":[{"@id":"https://journals.sagepub.com/doi/pdf/10.1177/17474930221138014"},{"@id":"https://journals.sagepub.com/doi/full-xml/10.1177/17474930221138014"}],"createdAt":"2022-10-28","modifiedAt":"2025-03-03","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Research","dc:title":"Research"},{"@id":"https://cir.nii.ac.jp/all?q=Endovascular%20Procedures","dc:title":"Endovascular Procedures"},{"@id":"https://cir.nii.ac.jp/all?q=East%20Asian%20People","dc:title":"East Asian People"},{"@id":"https://cir.nii.ac.jp/all?q=Brain%20Ischemia","dc:title":"Brain Ischemia"},{"@id":"https://cir.nii.ac.jp/all?q=Stroke","dc:title":"Stroke"},{"@id":"https://cir.nii.ac.jp/all?q=Treatment%20Outcome","dc:title":"Treatment Outcome"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Registries","dc:title":"Registries"},{"@id":"https://cir.nii.ac.jp/all?q=Aged","dc:title":"Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Thrombectomy","dc:title":"Thrombectomy"},{"@id":"https://cir.nii.ac.jp/all?q=Ischemic%20Stroke","dc:title":"Ischemic Stroke"},{"@id":"https://cir.nii.ac.jp/all?q=Retrospective%20Studies","dc:title":"Retrospective Studies"},{"@id":"https://cir.nii.ac.jp/all?q=Randomized%20Controlled%20Trials%20as%20Topic","dc:title":"Randomized Controlled Trials as Topic"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040858752029091200","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"23K11941"},{"@type":"JGN","@value":"JP23K11941"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K11941/"}],"notation":[{"@language":"ja","@value":"橈骨動脈アプローチによる脳カテーテル手技の安全性評価とトレーニングシステムの確立"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011145293905152","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017290209383680","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Functional Outcome Following Stroke Thrombectomy in Clinical Practice"}]},{"@id":"https://cir.nii.ac.jp/crid/1360021393787887360","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Safety and Outcome of Endovascular Treatment in Prestroke-Dependent Patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1360021394464254464","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Safety and outcomes of routine endovascular thrombectomy in large artery occlusion recorded in the SITS Register: An observational study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360302871115929984","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Direct admission versus secondary transfer for acute ischemic stroke patients treated with thrombectomy: a systematic review and meta-analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360584339779262976","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Increased door-to-puncture time during off-duty hours results in poor treatment outcomes for acute ischemic stroke: A subanalysis of the K-NET registry"}]},{"@id":"https://cir.nii.ac.jp/crid/1360584341833198080","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Ischemic stroke patients with low DWI ASPECTS scores require puncture to recanalization within 30 min for large vessel occlusion"}]},{"@id":"https://cir.nii.ac.jp/crid/1360865815512928640","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Efficacy and safety of thrombectomy for acute ischaemic stroke in patients with pre-stroke mRS scores of 2–3: Real-world evaluation from an open-label, prospective, multicentre, observational study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360865820402953600","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"First-line thrombectomy strategy for anterior large vessel occlusions: results of the prospective ETIS egistry"}]},{"@id":"https://cir.nii.ac.jp/crid/1360865820402993664","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Use of Imaging to Select Patients for Late Window Endovascular Therapy"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045924920832","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Early Ischemic Change on CT Versus Diffusion-Weighted Imaging for Patients With Stroke Receiving Intravenous Recombinant Tissue-Type Plasminogen Activator Therapy"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994016389888","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Association of Time From Stroke Onset to Groin Puncture With Quality of Reperfusion After Mechanical Thrombectomy"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994375126016","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699996307581184","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mothership versus drip and ship for thrombectomy in patients who had an acute stroke: a systematic review and meta-analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670319863468288","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670320899877888","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269675789568","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269828983296","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endovascular Therapy in Ischemic Stroke With Acute Large‐Vessel Occlusion: Recovery by Endovascular Salvage for Cerebral Ultra‐Acute Embolism Japan Registry 2"}]},{"@id":"https://cir.nii.ac.jp/crid/1390305201349644032","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Comparison of Aspiration and Stent Retriever in Acute Basilar Artery Occlusion: A Subanalysis of the K-NET Registry"}]},{"@id":"https://cir.nii.ac.jp/crid/1390860255282447872","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Registry Studies of Stroke in Japan"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1177/17474930221138014"},{"@type":"KAKEN","@value":"PRODUCT-24978772"},{"@type":"OPENAIRE","@value":"doi_dedup___::7d1b040a6393aa0752c5391a76b3a6d7"},{"@type":"CROSSREF","@value":"10.5797/jnet.oa.2025-0067_references_DOI_WLH9smwCiGl2xd0CApMY8JpZm2i"},{"@type":"CROSSREF","@value":"10.1177/15910199231205050_references_DOI_WLH9smwCiGl2xd0CApMY8JpZm2i"},{"@type":"CROSSREF","@value":"10.1016/j.jns.2023.120852_references_DOI_WLH9smwCiGl2xd0CApMY8JpZm2i"},{"@type":"CROSSREF","@value":"10.5551/jat.rv22008_references_DOI_WLH9smwCiGl2xd0CApMY8JpZm2i"},{"@type":"CROSSREF","@value":"10.1177/15910199231185637_references_DOI_WLH9smwCiGl2xd0CApMY8JpZm2i"}]}