{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360580239492874752.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1123/pes.2015-0122"}},{"identifier":{"@type":"URI","@value":"https://journals.humankinetics.com/view/journals/pes/28/2/article-p264.xml"}},{"identifier":{"@type":"URI","@value":"https://journals.humankinetics.com/downloadpdf/journals/pes/28/2/article-p264.xml"}}],"dc:title":[{"@value":"Obesity, Asthma, and Exercise in Child and Adolescent Health"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Obesity increases the risk of asthma throughout life but the underlying mechanisms linking these all too common threats to child health are poorly understood. Acute bouts of exercise, aerobic fitness, and levels of physical activity clearly play a role in the pathogenesis and/or management of both childhood obesity and asthma. Moreover, both obesity and physical inactivity are associated with asthma symptoms and response to therapy (a particularly challenging feature of obesity-related asthma). In this article, we review current understandings of the link between physical activity, aerobic fitness and the asthma-obesity link in children and adolescents (e.g., the impact of chronic low-grade inflammation, lung mechanics, and direct effects of metabolic health on the lung). Gaps in our knowledge regarding the physiological mechanisms linking asthma, obesity and exercise are often compounded by imprecise estimations of adiposity and challenges of assessing aerobic fitness in children. Addressing these gaps could lead to practical interventions and clinical approaches that could mitigate the profound health care crisis of the increasing comorbidity of asthma, physical inactivity, and obesity in children.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380580239492874755","@type":"Researcher","foaf:name":[{"@value":"Kim D. Lu"}],"jpcoar:affiliationName":[{"@value":"UC Irvine School of Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1380580239492874754","@type":"Researcher","foaf:name":[{"@value":"Krikor Manoukian"}],"jpcoar:affiliationName":[{"@value":"UC Irvine School of Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1380580239492874753","@type":"Researcher","foaf:name":[{"@value":"Shlomit Radom-Aizik"}],"jpcoar:affiliationName":[{"@value":"UC Irvine School of Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1380580239492874752","@type":"Researcher","foaf:name":[{"@value":"Dan M. Cooper"}],"jpcoar:affiliationName":[{"@value":"UC Irvine School of Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1380580239492874756","@type":"Researcher","foaf:name":[{"@value":"Stanley P. Galant"}],"jpcoar:affiliationName":[{"@value":"UC Irvine School of Medicine"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"08998493"},{"@type":"EISSN","@value":"15432920"}],"prism:publicationName":[{"@value":"Pediatric Exercise Science"}],"dc:publisher":[{"@value":"Human Kinetics"}],"prism:publicationDate":"2016-05","prism:volume":"28","prism:number":"2","prism:startingPage":"264","prism:endingPage":"274"},"reviewed":"false","url":[{"@id":"https://journals.humankinetics.com/view/journals/pes/28/2/article-p264.xml"},{"@id":"https://journals.humankinetics.com/downloadpdf/journals/pes/28/2/article-p264.xml"}],"createdAt":"2015-11-30","modifiedAt":"2025-08-27","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360021390753978752","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Prospective Real-World Analysis of Asthma Patients With Preserved and Reduced Physical Activity"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580229818198016","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1123/pes.2015-0122"},{"@type":"CROSSREF","@value":"10.1016/j.jaip.2023.04.040_references_DOI_GCzXHERacTy5U2tyS2QUSXcXB9L"},{"@type":"CROSSREF","@value":"10.1371/journal.pone.0266608_references_DOI_GCzXHERacTy5U2tyS2QUSXcXB9L"}]}