PRIASE 2021 guidelines for reporting animal studies in Endodontology: explanation and elaboration

DOI Web Site Web Site 2 Citations
  • M. H. Nekoofar
    Department of Endodontics School of Dentistry Tehran University of Medical Sciences Tehran Iran
  • J. A. P. de Figueiredo
    Federal University, Rio Grande do Sul Porto Alegre Brazil
  • E. Priya
    Division of Children and Community Oral Health School of Dentistry International Medical University Kuala Lumpur Malaysia
  • P. M. H. Dummer
    School of Dentistry College of Biomedical and Life Sciences Cardiff University Cardiff UK
  • A. Kishen
    Faculty of Dentistry University of Toronto Toronto ON Canada
  • J. Jayaraman
    Department of Developmental Dentistry University of Texas Health School of Dentistry San Antonio TX USA
  • V. Nagendrababu
    Department of Preventive and Restorative Dentistry College of Dental Medicine University of Sharjah Sharjah UAE
  • P. E. Murray
    Private Consultant Fort Lauderdale FL USA
  • A. Jakovljevic
    Department of Pathophysiology School of Dental Medicine University of Belgrade Belgrade Serbia
  • S. J. Pulikkotil
    Division of Clinical Dentistry School of Dentistry International Medical University Kuala Lumpur Malaysia

Bibliographic Information

Published
2021-03-07
Rights Information
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/iej.13481
Publisher
Wiley

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<jats:title>Abstract</jats:title><jats:p>Laws and ethics require that before conducting human clinical trials, a new material, device or drug may have to undergo testing in animals in order to minimize health risks to humans, unless suitable supporting <jats:italic>grandfather</jats:italic> data already exist. The Preferred Reporting Items for Animal Studies in Endodontology (PRIASE) 2021 guidelines were developed exclusively for the specialty of Endodontology by integrating and adapting the ARRIVE (Animals in Research: Reporting <jats:italic>In Vivo</jats:italic> Experiments) guidelines and the Clinical and Laboratory Images in Publications (CLIP) principles using a validated consensus‐based methodology. Implementation of the PRIASE 2021 guidelines will reduce potential sources of bias and thus improve the quality, accuracy, reproducibility, completeness and transparency of reports describing animal studies in Endodontology. The PRIASE 2021 guidelines consist of a checklist with 11 domains and 43 individual items and a flowchart. The aim of the current document is to provide an explanation for each item in the PRIASE 2021 checklist and flowchart and is supplemented with examples from the literature in order for readers to understand their significance and to provide usage guidance. A link to the PRIASE 2021 explanation and elaboration document and PRIASE 2021 checklist and flowchart is available on the Preferred Reporting Items for study Designs in Endodontology (PRIDE) website (<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="http://pride-endodonticguidelines.org/priase/">http://pride‐endodonticguidelines.org/priase/</jats:ext-link>).</jats:p>

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