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Conventional systems generally provide the probabilities of disease types in terms of numerical values, a method that may not be efficient for radiologists who are trained by reading a large number of images. Presentation of reference images similar to those of a new case being diagnosed can supplement the probability outputs based on computerized analysis as an intuitive guide, and it can assist radiologists in their diagnosis, reporting, and treatment planning. Many studies on content-based medical image retrievals have been reported on. For retrieval of perceptually similar and diagnostically relevant images, incorporation of perceptual similarity data by radiologists has been suggested. In this paper, studies on image retrieval methods are reviewed with a special focus on quantification, utilization, and the evaluation of subjective similarities between pairs of 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