Role of Dectin-2 in the Phagocytosis of Cryptococcus neoformans by Dendritic Cells

  • Yuki Kitai
    Department of Medical Microbiology, Mycology, and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Ko Sato
    Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Daiki Tanno
    Department of Medical Microbiology, Mycology, and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Xiaoliang Yuan
    Department of Medical Microbiology, Mycology, and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Aya Umeki
    Department of Medical Microbiology, Mycology, and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Jun Kasamatsu
    Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Emi Kanno
    Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Hiromasa Tanno
    Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Hiromitsu Hara
    Department of Immunology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
  • Sho Yamasaki
    Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
  • Shinobu Saijo
    Division of Molecular Immunology, Medical Mycology Research Center, Chiba University, Chiba, Japan
  • Yoichiro Iwakura
    Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba, Japan
  • Keiko Ishii
    Department of Medical Microbiology, Mycology, and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
  • Kazuyoshi Kawakami
    Department of Medical Microbiology, Mycology, and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

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説明

<jats:p> The cell walls and capsules of <jats:named-content content-type="genus-species">Cryptococcus neoformans</jats:named-content> , a yeast-type fungal pathogen, are rich in polysaccharides. Dectin-2 is a C-type lectin receptor (CLR) that recognizes high-mannose polysaccharides. </jats:p>

収録刊行物

  • Infection and Immunity

    Infection and Immunity 89 (10), e0033021-, 2021-09-16

    American Society for Microbiology

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