{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1360869854371956352.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1055/a-2207-7715"}},{"identifier":{"@type":"URI","@value":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-2207-7715.pdf"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"A Predictive Model for Cancer-Associated Thrombosis in Japanese Cancer Patients: Findings from the J-Khorana Registry"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>\n          Background Although the close relationship between cancer and venous thromboembolism (VTE) has been identified, risk stratification for VTE in Japanese patients with cancer remains unclear.</jats:p><jats:p>\n          Objectives This study aimed to validate the Khorana VTE risk assessment score (KRS) for VTE diagnosis and establish an optimal predictive model for VTE in Japanese patients with cancer.</jats:p><jats:p>\n          Methods A total of 7,955 Japanese patients with cancer were subdivided into low- (0), intermediate- (1–2), and high-score (3) groups according to the KRS. Using 37 explanatory variables, a total of 2,833 patients with cancer were divided into derivation and validation cohorts (5:5). A risk model for Japanese participants was developed using the derivation cohort data.</jats:p><jats:p>\n          Results The prevalence of VTE in low-, intermediate-, and high-score patients was 1.2, 2.5, and 4.3%, respectively. Logistic regression analysis demonstrated that cancer stage (III–IV) and KRS ≥ 2 were independent and significant predictors of VTE onset. The risk model for VTE assigned 1 point to body mass index ≥25 kg/m2 and 2 points each to the prevalence of osteochondral cancer and D-dimer level ≥1.47 µg/mL. The areas under the curve of the risk model were 0.763 and 0.656 in the derivation and validation cohorts, respectively.</jats:p><jats:p>\n          Conclusion The KRS was useful in Japanese patients, and our new predictive model may be helpful for the diagnosis of VTE in Japanese patients with cancer.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380869854371956489","@type":"Researcher","foaf:name":[{"@value":"Masaaki Shoji"}],"jpcoar:affiliationName":[{"@value":"Department of General Internal Medicine, National Cancer Center Hospital, Tokyo, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956493","@type":"Researcher","foaf:name":[{"@value":"Yugo Yamashita"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956488","@type":"Researcher","foaf:name":[{"@value":"Masanobu Ishii"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956483","@type":"Researcher","foaf:name":[{"@value":"Hitoki Inoue"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiology, National Hospital Organization (NHO) Hokkaido Cancer Center, Hokkaido, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956521","@type":"Researcher","foaf:name":[{"@value":"Hiroshi Kato"}],"jpcoar:affiliationName":[{"@value":"Division of Onco-Cardiology, Miyagi Cancer Center, Miyagi, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956512","@type":"Researcher","foaf:name":[{"@value":"Shin Fujita"}],"jpcoar:affiliationName":[{"@value":"Department of Surgery, Tochigi Cancer Center, Tochigi, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956355","@type":"Researcher","foaf:name":[{"@value":"Kazuhiro Matsui"}],"jpcoar:affiliationName":[{"@value":"Department of Internal Medicine, Onco-Cardiology Unit, Saitama Cancer Center, Saitama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956492","@type":"Researcher","foaf:name":[{"@value":"Kazuko Tajiri"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiology, National Cancer Center Hospital East, Chiba, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956497","@type":"Researcher","foaf:name":[{"@value":"Mizuo Nameki"}],"jpcoar:affiliationName":[{"@value":"Division of Cardiology, Chiba Cancer Center, Chiba, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956515","@type":"Researcher","foaf:name":[{"@value":"Nao Muraoka"}],"jpcoar:affiliationName":[{"@value":"Division of Cardiology, Shizuoka Cancer Center, Shizuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956484","@type":"Researcher","foaf:name":[{"@value":"Akiko Nonaka"}],"jpcoar:affiliationName":[{"@value":"Division of Onco-Cardiology, Hyogo Cancer Center, Hyogo, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956491","@type":"Researcher","foaf:name":[{"@value":"Hiroshi Sugino"}],"jpcoar:affiliationName":[{"@value":"Division of Cardiology, NHO Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956508","@type":"Researcher","foaf:name":[{"@value":"Mihoko Kono"}],"jpcoar:affiliationName":[{"@value":"Department of Onco-Cardiology, NHO Kyushu Cancer Center, Fukuoka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956357","@type":"Researcher","foaf:name":[{"@value":"Toru Oka"}],"jpcoar:affiliationName":[{"@value":"Department of Internal Medicine, Onco-Cardiology Unit, Saitama Cancer Center, Saitama, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1420564276166610944","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70750040"},{"@type":"NRID","@value":"1000070750040"},{"@type":"NRID","@value":"9000415313860"},{"@type":"NRID","@value":"9000319551071"},{"@type":"NRID","@value":"9000345371986"},{"@type":"NRID","@value":"9000411005796"},{"@type":"NRID","@value":"9000006808473"},{"@type":"NRID","@value":"9000345298556"},{"@type":"NRID","@value":"9000403033567"},{"@type":"NRID","@value":"9000410737730"},{"@type":"NRID","@value":"9000415204468"},{"@type":"NRID","@value":"9000406388294"},{"@type":"NRID","@value":"9000399224889"},{"@type":"NRID","@value":"9000408424661"},{"@type":"NRID","@value":"9000391593201"},{"@type":"NRID","@value":"9000296663907"},{"@type":"NRID","@value":"9000411507083"},{"@type":"NRID","@value":"9000403033594"},{"@type":"NRID","@value":"9000404853524"},{"@type":"NRID","@value":"9000413887824"},{"@type":"NRID","@value":"9000413543252"},{"@type":"NRID","@value":"9000409597717"},{"@type":"NRID","@value":"9000414546742"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/7000017013"}],"foaf:name":[{"@value":"Daisuke Sueta"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956365","@type":"Researcher","foaf:name":[{"@value":"Issei Komuro"}],"jpcoar:affiliationName":[{"@value":"Department of Frontier Cardiovascular Science, International University of Health and Welfare, Tokyo, Japan"},{"@value":"Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1380869854371956505","@type":"Researcher","foaf:name":[{"@value":"Kenichi Tsujita"}],"jpcoar:affiliationName":[{"@value":"Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"25129465"},{"@type":"PISSN","@value":"https://id.crossref.org/issn/25129465"}],"prism:publicationName":[{"@value":"TH Open"}],"dc:publisher":[{"@value":"Georg Thieme Verlag KG"}],"prism:publicationDate":"2023-11-09","prism:volume":"08","prism:number":"01","prism:startingPage":"e9","prism:endingPage":"e18"},"reviewed":"false","dc:rights":["https://creativecommons.org/licenses/by/4.0/"],"url":[{"@id":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-2207-7715.pdf"}],"createdAt":"2023-11-10","modifiedAt":"2024-11-05","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=predictive%20model","dc:title":"predictive model"},{"@id":"https://cir.nii.ac.jp/all?q=RC666-701","dc:title":"RC666-701"},{"@id":"https://cir.nii.ac.jp/all?q=venous%20thromboembolism","dc:title":"venous thromboembolism"},{"@id":"https://cir.nii.ac.jp/all?q=cancer","dc:title":"cancer"},{"@id":"https://cir.nii.ac.jp/all?q=Diseases%20of%20the%20circulatory%20(Cardiovascular)%20system","dc:title":"Diseases of the circulatory (Cardiovascular) 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