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The EEPs were elicited by 1 to 5 mA of transcorneal electrical stimulation. The first positive wave, the P1 component, was analyzed. After euthanasia, the number of axons in the optic nerve was counted.The threshold current to elicit a P1 was significantly higher in Tg rabbits than WT rabbits. The amplitude of P1 elicited by 5 mA in Tg rabbits was about 24% of that in WT rabbits (P0.01). The number of axons in the optic nerve of Tg rabbits was reduced to about 59% of that of WT rabbits (P0.01). The correlation between the axon number and the amplitude of the P1 in Tg and WT rabbits was not significant. The mean ratio of the P1 amplitude/axon in Tg rabbits was decreased to 53% of that in WT rabbits (P0.05).The degree of reduction in the EEP in Tg rabbits is more severe than the reduction in the number of optic nerve axons. The use of transcorneal electrical stimulation to determine the suitable candidates for prosthesis at the end-stage of retinitis pigmentosa may underestimate the condition of the optic nerves."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381131421492436481","@type":"Researcher","foaf:name":[{"@value":"Taro Kominami"}],"jpcoar:affiliationName":[{"@value":"Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1420564276167458560","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"80528670"},{"@type":"NRID","@value":"1000080528670"},{"@type":"NRID","@value":"9000402118746"},{"@type":"NRID","@value":"9000001828774"},{"@type":"NRID","@value":"9000415224215"},{"@type":"NRID","@value":"9000415075073"}],"foaf:name":[{"@value":"Shinji Ueno"}],"jpcoar:affiliationName":[{"@value":"Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381131421492436609","@type":"Researcher","foaf:name":[{"@value":"Kentaro Nishida"}],"jpcoar:affiliationName":[{"@value":"Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381131421492436353","@type":"Researcher","foaf:name":[{"@value":"Daiki Inooka"}],"jpcoar:affiliationName":[{"@value":"Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381131421492436482","@type":"Researcher","foaf:name":[{"@value":"Azusa Kominami"}],"jpcoar:affiliationName":[{"@value":"Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, 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Terasaki"}],"jpcoar:affiliationName":[{"@value":"Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"15525783"}],"prism:publicationName":[{"@value":"Investigative Opthalmology & Visual Science"}],"dc:publisher":[{"@value":"Association for Research in Vision and Ophthalmology (ARVO)"}],"prism:publicationDate":"2019-06-17","prism:volume":"60","prism:number":"7","prism:startingPage":"2543"},"reviewed":"false","dc:rights":["http://creativecommons.org/licenses/by-nc-nd/4.0/"],"url":[{"@id":"http://iovs.arvojournals.org/article.aspx?articleid=2736343"}],"createdAt":"2019-06-17","modifiedAt":"2019-06-17","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Rhodopsin","dc:title":"Rhodopsin"},{"@id":"https://cir.nii.ac.jp/all?q=Cell%20Count","dc:title":"Cell Count"},{"@id":"https://cir.nii.ac.jp/all?q=Optic%20Nerve","dc:title":"Optic Nerve"},{"@id":"https://cir.nii.ac.jp/all?q=Axons","dc:title":"Axons"},{"@id":"https://cir.nii.ac.jp/all?q=Electric%20Stimulation","dc:title":"Electric Stimulation"},{"@id":"https://cir.nii.ac.jp/all?q=Animals,%20Genetically%20Modified","dc:title":"Animals, Genetically Modified"},{"@id":"https://cir.nii.ac.jp/all?q=Disease%20Models,%20Animal","dc:title":"Disease Models, Animal"},{"@id":"https://cir.nii.ac.jp/all?q=Animals","dc:title":"Animals"},{"@id":"https://cir.nii.ac.jp/all?q=Evoked%20Potentials,%20Visual","dc:title":"Evoked Potentials, Visual"},{"@id":"https://cir.nii.ac.jp/all?q=Rabbits","dc:title":"Rabbits"},{"@id":"https://cir.nii.ac.jp/all?q=Retinitis%20Pigmentosa","dc:title":"Retinitis Pigmentosa"},{"@id":"https://cir.nii.ac.jp/all?q=Photoreceptor%20Cells,%20Vertebrate","dc:title":"Photoreceptor Cells, 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