{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137043407448704.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3390/s120302456"}},{"identifier":{"@type":"URI","@value":"https://www.mdpi.com/1424-8220/12/3/2456/pdf"}}],"dc:title":[{"@value":"Electrochemical L-Lactic Acid Sensor Based on Immobilized ZnO Nanorods with Lactate Oxidase"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>In this work, fabrication of gold coated glass substrate, growth of ZnO nanorods and potentiometric response of lactic acid are explained. The biosensor was developed by immobilizing the lactate oxidase on the ZnO nanorods in combination with glutaraldehyde as a cross linker for lactate oxidase enzyme. The potentiometric technique was applied for the measuring the output (EMF) response of L-lactic acid biosensor. We noticed that the present biosensor has wide linear detection range of concentration from 1 × 10−4–1 × 100 mM with acceptable sensitivity about 41.33 ± 1.58 mV/decade. In addition, the proposed biosensor showed fast response time less than 10 s, a good selectivity towards L-lactic acid in presence of common interfering substances such as ascorbic acid, urea, glucose, galactose, magnesium ions and calcium ions. The present biosensor based on immobilized ZnO nanorods with lactate oxidase sustained its stability for more than three weeks.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381137043407448707","@type":"Researcher","foaf:name":[{"@value":"Zafar Hussain Ibupoto"}],"jpcoar:affiliationName":[{"@value":"Department of Science and Technology, Campus Norrköping, Linköping University, SE-60174, Norrköping, Sweden"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043407448704","@type":"Researcher","foaf:name":[{"@value":"Syed Muhammad Usman Ali Shah"}],"jpcoar:affiliationName":[{"@value":"Department of Science and Technology, Campus Norrköping, Linköping University, SE-60174, Norrköping, Sweden"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043407448705","@type":"Researcher","foaf:name":[{"@value":"Magnus Willander"}],"jpcoar:affiliationName":[{"@value":"Department of Science and Technology, Campus Norrköping, Linköping University, SE-60174, Norrköping, Sweden"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043407448706","@type":"Researcher","foaf:name":[{"@value":"Kimleang Khun"}],"jpcoar:affiliationName":[{"@value":"Department of Science and Technology, Campus Norrköping, Linköping University, SE-60174, Norrköping, Sweden"}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"14248220"}],"prism:publicationName":[{"@value":"Sensors"}],"dc:publisher":[{"@value":"MDPI AG"}],"prism:publicationDate":"2012-02-23","prism:volume":"12","prism:number":"3","prism:startingPage":"2456","prism:endingPage":"2466"},"reviewed":"false","dc:rights":["https://creativecommons.org/licenses/by/3.0/"],"url":[{"@id":"https://www.mdpi.com/1424-8220/12/3/2456/pdf"}],"createdAt":"2012-02-23","modifiedAt":"2025-10-11","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360002215830311296","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A novel OFET-based biosensor for the selective and sensitive detection of lactate levels"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294643844882560","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"<i>In Situ</i> Single-Cell Stimulation and Real-Time Electrochemical Detection of Lactate Response Using a Microfluidic Probe"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.3390/s120302456"},{"@type":"CROSSREF","@value":"10.1021/acs.analchem.1c01054_references_DOI_CsES5gd7KmEdCmmV6OlYeQJPxne"},{"@type":"CROSSREF","@value":"10.1016/j.bios.2015.06.002_references_DOI_CsES5gd7KmEdCmmV6OlYeQJPxne"}]}