{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137043686593408.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1212/01.wnl.0000144274.12174.cb"}},{"identifier":{"@type":"URI","@value":"https://www.neurology.org/doi/pdfdirect/10.1212/01.WNL.0000144274.12174.CB"}},{"identifier":{"@type":"PMID","@value":"15858866"}}],"dc:title":[{"@value":"Clinically mild encephalitis/encephalopathy with a reversible splenial lesion"}],"description":[{"notation":[{"@value":"To clarify whether patients with clinical diagnoses of encephalitis/encephalopathy with a reversible lesion in the splenium of the corpus callosum (SCC) share common clinical features.Possible encephalitis/encephalopathy patients with a reversible isolated SCC lesion on MRI were collected retrospectively. Their clinical, laboratory, and radiologic data were reviewed.Fifteen encephalitis/encephalopathy patients with a reversible isolated SCC lesion were identified among 22 patients referred for this study. All 15 patients had relatively mild clinical courses. Twelve of the 15 patients had disorders of consciousness. Eight patients had seizures, and three of them received antiepileptic drugs. All 15 patients clinically recovered completely within 1 month (8 patients within a week) after the onset of neurologic symptoms. The SCC lesion was ovoid in six patients; it extended irregularly from the center to the lateral portion of SCC in the other eight patients. Homogeneously reduced diffusion was seen in all seven patients who underwent diffusion-weighted imaging. There was no enhancement in the five patients so examined. The SCC lesion had completely disappeared in all patients at follow-up MRI exams between 3 days and 2 months after the initial MRI (within 1 week in eight patients).The clinical features among the affected patients were nearly identical, consisting of relatively mild CNS manifestations and complete recovery within 1 month."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380004236857696905","@type":"Researcher","foaf:name":[{"@value":"H. Tada"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593415","@type":"Researcher","foaf:name":[{"@value":"J. Takanashi"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593413","@type":"Researcher","foaf:name":[{"@value":"A. J. Barkovich"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593419","@type":"Researcher","foaf:name":[{"@value":"H. Oba"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593416","@type":"Researcher","foaf:name":[{"@value":"M. Maeda"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593414","@type":"Researcher","foaf:name":[{"@value":"H. Tsukahara"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593412","@type":"Researcher","foaf:name":[{"@value":"M. Suzuki"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593418","@type":"Researcher","foaf:name":[{"@value":"T. Yamamoto"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593420","@type":"Researcher","foaf:name":[{"@value":"T. Shimono"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593411","@type":"Researcher","foaf:name":[{"@value":"T. Ichiyama"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593410","@type":"Researcher","foaf:name":[{"@value":"T. Taoka"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593536","@type":"Researcher","foaf:name":[{"@value":"O. Sohma"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593408","@type":"Researcher","foaf:name":[{"@value":"H. Yoshikawa"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137043686593417","@type":"Researcher","foaf:name":[{"@value":"Y. Kohno"}],"jpcoar:affiliationName":[{"@value":"From the Department of Pediatrics (Drs. Tada, Takanashi, and Kohno), Chiba University Graduate School of Medicine, Chiba, Department of Radiology (Dr. Oba), Teikyo University School of Medicine, Tokyo, Department of Radiology (Dr. Maeda), Mie University School of Medicine, Mie, Department of Pediatrics (Dr. Tsukahara), Faculty of Medical Sciences, University of Fukui, Fukui, Department of Pediatrics (Dr. Suzuki), Okazaki City Hospital, Okazaki, Division of Medical Genetics (Dr. Yamamoto), Kanagawa..."}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00283878"},{"@type":"EISSN","@value":"1526632X"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/00283878"},{"@type":"PISSN","@value":"https://id.crossref.org/issn/00283878"}],"prism:publicationName":[{"@value":"Neurology"}],"dc:publisher":[{"@value":"Ovid Technologies (Wolters Kluwer Health)"}],"prism:publicationDate":"2004-11-23","prism:volume":"63","prism:number":"10","prism:startingPage":"1854","prism:endingPage":"1858"},"reviewed":"false","url":[{"@id":"https://www.neurology.org/doi/pdfdirect/10.1212/01.WNL.0000144274.12174.CB"}],"createdAt":"2012-05-13","modifiedAt":"2024-03-28","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Adult","dc:title":"Adult"},{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Brain%20Diseases","dc:title":"Brain Diseases"},{"@id":"https://cir.nii.ac.jp/all?q=Adolescent","dc:title":"Adolescent"},{"@id":"https://cir.nii.ac.jp/all?q=Remission,%20Spontaneous","dc:title":"Remission, Spontaneous"},{"@id":"https://cir.nii.ac.jp/all?q=Middle%20Aged","dc:title":"Middle Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Corpus%20Callosum","dc:title":"Corpus Callosum"},{"@id":"https://cir.nii.ac.jp/all?q=Diffusion%20Magnetic%20Resonance%20Imaging","dc:title":"Diffusion Magnetic Resonance Imaging"},{"@id":"https://cir.nii.ac.jp/all?q=Meningoencephalitis","dc:title":"Meningoencephalitis"},{"@id":"https://cir.nii.ac.jp/all?q=Seizures","dc:title":"Seizures"},{"@id":"https://cir.nii.ac.jp/all?q=Child,%20Preschool","dc:title":"Child, Preschool"},{"@id":"https://cir.nii.ac.jp/all?q=Consciousness%20Disorders","dc:title":"Consciousness Disorders"},{"@id":"https://cir.nii.ac.jp/all?q=Encephalitis","dc:title":"Encephalitis"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Anticonvulsants","dc:title":"Anticonvulsants"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Encephalitis,%20Viral","dc:title":"Encephalitis, Viral"},{"@id":"https://cir.nii.ac.jp/all?q=Child","dc:title":"Child"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050863629122626560","@type":"Article","resourceType":"学術雑誌論文(journal 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Accompanied by Epstein-Barr Virus Hemophagocytic Lymphohistiocytosis: A Case Report and Review of the Literature"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142632125952","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A trial of lacosamide for benign convulsions with gastroenteritis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142697145728","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Clinical Features of Cytotoxic Lesions of the Corpus Callosum Associated with Aneurysmal Subarachnoid Hemorrhage"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013168806945024","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Increased cytokines/chemokines and hyponatremia as a possible cause of clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with acute focal bacterial nephritis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360017279839516928","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Case report: Mild encephalitis with a reversible splenial lesion associated with SARS-CoV-2 infection in a patient with MYRF variant"}]},{"@id":"https://cir.nii.ac.jp/crid/1360025430638533120","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"International consensus definitions for infection‐triggered encephalopathy syndromes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285707111443712","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"White matter abnormalities in patients with temporal lobe epilepsy and amygdala enlargement: Comparison with hippocampal sclerosis and healthy 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Infection"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285714961441920","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Abscess in the Splenium of the Corpus Callosum Treated with Direct Drainage via an Occipital Interhemispheric Approach"}]},{"@id":"https://cir.nii.ac.jp/crid/1360290617662436992","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Guidelines for the diagnosis and treatment of acute encephalopathy in childhood"}]},{"@id":"https://cir.nii.ac.jp/crid/1360298755630212864","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Severe pediatric acute encephalopathy syndromes related to SARS-CoV-2"}]},{"@id":"https://cir.nii.ac.jp/crid/1360306904399712640","@type":"Article","resourceType":"学術雑誌論文(journal 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encephalitis/encephalopathy with transient splenial lesion"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567182254055552","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Clinically mild encephalitis with a reversible splenial lesion (MERS) after mumps vaccination"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567182254292224","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Reversible splenial lesion of the corpus callosum associated with meningococcal meningitis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567187942160000","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Late Delirious Behavior With 2009 H1N1 Influenza: Mild Autoimmune-Mediated Encephalitis?"}]},{"@id":"https://cir.nii.ac.jp/crid/1360568466651206400","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Serum and cerebrospinal fluid cytokines in children with acute encephalopathy"}]},{"@id":"https://cir.nii.ac.jp/crid/1360568466651223680","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Epidemiological changes of acute encephalopathy in Japan based on national surveillance for 2014–2017"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576118722123904","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Cerebral Blood Flow Abnormalities Associated With Clinically Mild Encephalopathy With a Reversible Splenial Lesion Type 2"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580230580903680","@type":"Article","resourceType":"学術雑誌論文(journal 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