{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137044220464896.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1053/j.gastro.2007.01.046"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0016508507001850?httpAccept=text/xml"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0016508507001850?httpAccept=text/plain"}}],"dc:title":[{"@value":"Immune Activation in Patients With Irritable Bowel Syndrome"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381137044220465025","@type":"Researcher","foaf:name":[{"@value":"Tobias Liebregts"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220465024","@type":"Researcher","foaf:name":[{"@value":"Birgit Adam"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220464898","@type":"Researcher","foaf:name":[{"@value":"Christoph Bredack"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220465027","@type":"Researcher","foaf:name":[{"@value":"Alexander Röth"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220465026","@type":"Researcher","foaf:name":[{"@value":"Susanne Heinzel"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220464899","@type":"Researcher","foaf:name":[{"@value":"Sue Lester"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220465030","@type":"Researcher","foaf:name":[{"@value":"Sarah Downie–Doyle"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220465029","@type":"Researcher","foaf:name":[{"@value":"Eric Smith"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220465028","@type":"Researcher","foaf:name":[{"@value":"Paul Drew"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220464897","@type":"Researcher","foaf:name":[{"@value":"Nicholas J. Talley"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044220464896","@type":"Researcher","foaf:name":[{"@value":"Gerald Holtmann"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00165085"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/00165085"}],"prism:publicationName":[{"@value":"Gastroenterology"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2007-03","prism:volume":"132","prism:number":"3","prism:startingPage":"913","prism:endingPage":"920"},"reviewed":"false","dc:rights":["https://www.elsevier.com/tdm/userlicense/1.0/"],"url":[{"@id":"https://api.elsevier.com/content/article/PII:S0016508507001850?httpAccept=text/xml"},{"@id":"https://api.elsevier.com/content/article/PII:S0016508507001850?httpAccept=text/plain"}],"createdAt":"2007-01-27","modifiedAt":"2023-05-10","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050018296277441152","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Lovastatin inhibits visceral allodynia and increased colonic permeability induced by lipopolysaccharide or repeated water avoidance stress in rats."}]},{"@id":"https://cir.nii.ac.jp/crid/1050585803064890112","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Peripheral apelin mediates visceral hypersensitivity and impaired gut barrier in a rat irritable bowel syndrome model"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004235779801472","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004236401514240","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pathogenesis of Irritable Bowel Syndrome - Review Regarding Associated Infection and Immune Activation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004237936272768","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Altered colonic sensory and barrier functions by CRF: roles of TLR4 and IL-1"}]},{"@id":"https://cir.nii.ac.jp/crid/1360016864709012608","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pathophysiological Commonality Between Irritable Bowel Syndrome and Metabolic Syndrome: Role of Corticotropin-releasing Factor-Toll-like Receptor 4-Proinflammatory Cytokine Signaling"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285706237557120","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Colorectal distention induces acute and delayed visceral hypersensitivity: role of peripheral corticotropin-releasing factor and interleukin-1 in rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285707291754368","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pioglitazone improves visceral sensation and colonic permeability in a rat model of irritable bowel syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285710756309504","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Repeated water avoidance stress induces visceral hypersensitivity: Role of interleukin‐1, interleukin‐6, and peripheral corticotropin‐releasing factor"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567181214522112","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Lipopolysaccharide induces visceral hypersensitivity: role of interleukin-1, interleukin-6, and peripheral corticotropin-releasing factor in rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567184575155200","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Phase separation of myelin sheath in Triton X-114 solution: predominant localization of the 21.5-kDa isoform of myelin basic protein in the lipid raft-associated domain"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846643266865792","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Glucagon‐like peptide‐1 analog, liraglutide, improves visceral sensation and gut permeability in rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846646019685376","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Biopsychosocial Model of Irritable Bowel Syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1360849943307694208","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Butyrate inhibits visceral allodynia and colonic hyperpermeability in rat models of irritable bowel syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1361975841508665856","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The role of peripheral corticotropin-releasing factor signaling in a rat model of stress-induced gastric hyperalgesia"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204667431040","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Probiotics and Irritable Bowel Syndrome"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1053/j.gastro.2007.01.046"},{"@type":"CROSSREF","@value":"10.1111/jgh.14367_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1530/joe-18-0441_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1016/j.npep.2022.102248_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.5056/jnm21002_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1007/s00535-015-1070-3_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1111/jgh.13787_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1016/j.jphs.2018.11.006_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1007/s00535-016-1208-y_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1093/jb/mvu005_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1159/000350054_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1111/jgh.13808_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.5056/jnm.2011.17.2.131_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1038/s41598-019-56132-4_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1016/j.ejphar.2017.10.056_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.12938/bifidus.28.119_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"},{"@type":"CROSSREF","@value":"10.1016/j.bbrc.2019.09.040_references_DOI_J08zHusyzrhF0tVK2qF2gJGY93c"}]}