{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137044710115968.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/anie.201609337"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fanie.201609337"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201609337"}}],"dc:title":[{"@value":"An Enantioselective Bidentate Auxiliary Directed Palladium‐Catalyzed Benzylic C−H Arylation of Amines Using a BINOL Phosphate Ligand"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>A new enantioselective palladium(II)‐catalyzed benzylic C−H arylation reaction of amines is enabled by the bidentate picolinamide (PA) directing group. This reaction provides the first example of enantioselective benzylic γ‐C−H arylations of alkyl amines, and proceeds with up to 97 % <jats:italic>ee</jats:italic>. The 2,2′‐dihydroxy‐1,1′‐binaphthyl (BINOL) phosphoric acid ligand, Cs<jats:sub>2</jats:sub>CO<jats:sub>3</jats:sub>, and solvent‐free conditions are essential for high enantioselectivity. Mechanistic studies suggest that multiple BINOL ligands are involved in the stereodetermining C−H palladation step.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381137044710115969","@type":"Researcher","foaf:name":[{"@value":"Hao Wang"}],"jpcoar:affiliationName":[{"@value":"State Key Laboratory and Institute of Elemento-Organic Chemistry Collaborative Innovation, Center of Chemical Science and Engineering (Tianjin) Nankai University  Tianjin 300071 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1380016866269787648","@type":"Researcher","foaf:name":[{"@value":"Hua‐Rong Tong"}],"jpcoar:affiliationName":[{"@value":"State Key Laboratory and Institute of Elemento-Organic Chemistry Collaborative Innovation, Center of Chemical Science and Engineering (Tianjin) Nankai University  Tianjin 300071 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044710115968","@type":"Researcher","foaf:name":[{"@value":"Gang He"}],"jpcoar:affiliationName":[{"@value":"State Key Laboratory and Institute of Elemento-Organic Chemistry Collaborative Innovation, Center of Chemical Science and Engineering (Tianjin) Nankai University  Tianjin 300071 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044710115970","@type":"Researcher","foaf:name":[{"@value":"Gong Chen"}],"jpcoar:affiliationName":[{"@value":"State Key Laboratory and Institute of Elemento-Organic Chemistry Collaborative Innovation, Center of Chemical Science and Engineering (Tianjin) Nankai University  Tianjin 300071 China"},{"@value":"Department of Chemistry The Pennsylvania State University  University Park Pennsylvania 16802 USA"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"14337851"},{"@type":"EISSN","@value":"15213773"}],"prism:publicationName":[{"@value":"Angewandte Chemie International 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