{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137044784209792.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1161/strokeaha.111.617415"}},{"identifier":{"@type":"URI","@value":"https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.111.617415"}},{"identifier":{"@type":"PMID","@value":"21817134"}}],"dc:title":[{"@value":"Prestroke Glycemic Control Is Associated With the Functional Outcome in Acute Ischemic Stroke"}],"dcterms:alternative":[{"@value":"The Fukuoka Stroke Registry"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:sec>\n            <jats:title>Background and Purpose—</jats:title>\n            <jats:p>Diabetes mellitus is an established risk factor for stroke. However, it is uncertain whether prestroke glycemic control (PSGC) status affects clinical outcomes of acute ischemic stroke. The aim of this study was to elucidate the association between PSGC status and neurological or functional outcomes in patients with acute ischemic stroke.</jats:p>\n          </jats:sec>\n          <jats:sec>\n            <jats:title>Methods—</jats:title>\n            <jats:p>From the Fukuoka Stroke Registry (FSR), a multicenter stroke registry in Japan, 3627 patients with first-ever ischemic stroke within 24 hours after onset were included in the present analysis. The patients were categorized into 4 groups based on their PSGC status: excellent (hemoglobin [Hb] A1c on admission <6.2%), good (6.2–6.8%), fair (6.9–8.3%) and poor (≥8.4%). Study outcomes were neurological improvement (≥4 points decrease in the National Institutes of Health Stroke Scale [NIHSS] score during hospitalization or 0 points on NIHSS score at discharge), neurological deterioration (≥1 point increase in NIHSS score) and poor functional outcome (death or dependency at discharge, modified Rankin Scale 2–6).</jats:p>\n          </jats:sec>\n          <jats:sec>\n            <jats:title>Results—</jats:title>\n            <jats:p>The age- and sex-adjusted ORs for neurological improvement were lower, and those for neurological deterioration and a poor functional outcome were higher in patients with poorer PSGC status. After adjusting for multiple confounding factors, these trends were unchanged (all probability values for trends were <0.002). These findings were comparable in patients with noncardioembolic and cardioembolic infarctions.</jats:p>\n          </jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions—</jats:title>\n            <jats:p>In ischemic stroke patients, HbA1c on admission was an independent significant predictor for neurological and functional outcomes.</jats:p>\n          </jats:sec>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381137044784209667","@type":"Researcher","foaf:name":[{"@value":"Masahiro Kamouchi"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044784209666","@type":"Researcher","foaf:name":[{"@value":"Takayuki Matsuki"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044784209795","@type":"Researcher","foaf:name":[{"@value":"Jun Hata"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044784209796","@type":"Researcher","foaf:name":[{"@value":"Takahiro Kuwashiro"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044784209794","@type":"Researcher","foaf:name":[{"@value":"Tetsuro Ago"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044784209792","@type":"Researcher","foaf:name":[{"@value":"Yoshiki Sambongi"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044784209664","@type":"Researcher","foaf:name":[{"@value":"Yoshihisa Fukushima"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044784209665","@type":"Researcher","foaf:name":[{"@value":"Hiroshi Sugimori"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137044784209793","@type":"Researcher","foaf:name":[{"@value":"Takanari Kitazono"}],"jpcoar:affiliationName":[{"@value":"From the Department of Nephrology, Hypertension, and Strokology (M.K., T.A., T.K.), Department of Medicine and Clinical Science (M.K., T.M., J.H., T.K., T.A., Y.S., Y.F., H.S., T.K.), Department of Environmental Medicine (J.H.), and the Emergency and Critical Care Center (T.K., H.S.), Kyushu University, Fukuoka, Japan."}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00392499"},{"@type":"EISSN","@value":"15244628"}],"prism:publicationName":[{"@value":"Stroke"}],"dc:publisher":[{"@value":"Ovid Technologies (Wolters Kluwer Health)"}],"prism:publicationDate":"2011-10","prism:volume":"42","prism:number":"10","prism:startingPage":"2788","prism:endingPage":"2794"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.111.617415"}],"createdAt":"2011-08-05","modifiedAt":"2024-05-13","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Aged,%2080%20and%20over","dc:title":"Aged, 80 and over"},{"@id":"https://cir.nii.ac.jp/all?q=Blood%20Glucose","dc:title":"Blood Glucose"},{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Middle%20Aged","dc:title":"Middle Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Prognosis","dc:title":"Prognosis"},{"@id":"https://cir.nii.ac.jp/all?q=Severity%20of%20Illness%20Index","dc:title":"Severity of Illness Index"},{"@id":"https://cir.nii.ac.jp/all?q=Brain%20Ischemia","dc:title":"Brain Ischemia"},{"@id":"https://cir.nii.ac.jp/all?q=Stroke","dc:title":"Stroke"},{"@id":"https://cir.nii.ac.jp/all?q=Treatment%20Outcome","dc:title":"Treatment Outcome"},{"@id":"https://cir.nii.ac.jp/all?q=Japan","dc:title":"Japan"},{"@id":"https://cir.nii.ac.jp/all?q=Risk%20Factors","dc:title":"Risk Factors"},{"@id":"https://cir.nii.ac.jp/all?q=Hyperglycemia","dc:title":"Hyperglycemia"},{"@id":"https://cir.nii.ac.jp/all?q=Diabetes%20Mellitus","dc:title":"Diabetes Mellitus"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Hypoglycemic%20Agents","dc:title":"Hypoglycemic Agents"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Registries","dc:title":"Registries"},{"@id":"https://cir.nii.ac.jp/all?q=Aged","dc:title":"Aged"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050580605009684352","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Control of Diabetes Mellitus and Long-Term Prognosis in Stroke Patients: The Shiga Stroke and Heart Attack Registry"}]},{"@id":"https://cir.nii.ac.jp/crid/1050587970430477440","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"β-Cell Function and Clinical Outcome in Nondiabetic Patients With Acute Ischemic Stroke"}]},{"@id":"https://cir.nii.ac.jp/crid/1360002218732688640","@type":"Article","resourceType":"学術雑誌論文(journal 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