{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137045106526592.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/jssc.200600002"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjssc.200600002"}},{"identifier":{"@type":"URI","@value":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/pdf/10.1002/jssc.200600002"}},{"identifier":{"@type":"NAID","@value":"80018958694"}}],"dc:title":[{"@value":"Isotope‐ratio detection for gas chromatography"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>Instrumentation and methods exist for highly precise analyses of the stable‐isotopic composition of organic compounds separated by GC. The general approach combines a conventional GC, a chemical reaction interface, and a specialized isotope‐ratio mass spectrometer (IRMS). Most existing GC hardware and methods are amenable to isotope‐ratio detection. The interface continuously and quantitatively converts all organic matter, including column bleed, to a common molecular form for isotopic measurement. C and N are analyzed as CO<jats:sub>2</jats:sub> and N<jats:sub>2</jats:sub>, respectively, derived from combustion of analytes. H and O are analyzed as H<jats:sub>2</jats:sub> and CO produced by pyrolysis/reduction. IRMS instruments are optimized to provide intense, highly stable ion beams, with extremely high precision realized <jats:italic>via</jats:italic> a system of differential measurements in which ion currents for all major isotopologs are simultaneously monitored. Calibration to an internationally recognized scale is achieved through comparison of closely spaced sample and standard peaks. Such systems are capable of measuring <jats:sup>13</jats:sup>C/<jats:sup>12</jats:sup>C ratios with a precision approaching 0.1‰ (for values reported in the standard delta notation), four orders of magnitude better than that typically achieved by conventional “organic” mass spectrometers. Detection limits to achieve this level of precision are typically <1 nmol C (roughly 10 ng of a typical hydrocarbon) injected on‐column. Achievable precision and detection limits are correspondingly higher for N, O, and H, in that order.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381137045106526592","@type":"Researcher","foaf:name":[{"@value":"Alex L. Sessions"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"16159306"},{"@type":"EISSN","@value":"16159314"}],"prism:publicationName":[{"@value":"Journal of Separation Science"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2006-08","prism:volume":"29","prism:number":"12","prism:startingPage":"1946","prism:endingPage":"1961"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjssc.200600002"},{"@id":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/pdf/10.1002/jssc.200600002"}],"createdAt":"2006-07-20","modifiedAt":"2025-10-19","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360283691084155392","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Advances in the application of amino acid nitrogen isotopic analysis in ecological and biogeochemical studies"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285705266231936","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Determination of carbon isotope ratios for honey samples by means of a liquid chromatography/isotope ratio mass spectrometry system coupled with a post‐column pump"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567180163073920","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A new analytical method for determination of the nitrogen isotopic composition of methionine: Its application to aquatic ecosystems with mixed resources"}]},{"@id":"https://cir.nii.ac.jp/crid/1360865815494794240","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Stable Carbon Isotope Ratio of Volatile Organic Compounds in Air Using Solid-Phase Microextraction Coupled with Chromatography, Combustion, and Isotope Ratio Mass Spectrometry"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001206129190016","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"安定同位体比分析を用いた酒類原料の起源推定技術について"},{"@language":"en","@value":"Analysis of Stable Isotope Ratio for Discrimination of Origin of Ethanol"},{"@language":"ja-Kana","@value":"アンテイ ドウイタイヒ ブンセキ オ モチイタ サケルイ ゲンリョウ ノ キゲン スイテイ ギジュツ ニ ツイテ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680389439360","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"脂質・色素分子の安定水素同位体組成"},{"@language":"en","@value":"Stable hydrogen isotopic composition of lipids and pigments"},{"@language":"ja-Kana","@value":"シシツ シキソ ブンシ ノ アンテイ スイソ ドウイタイ ソセイ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680389625856","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"ガスクロマトグラフ/同位体比質量分析計による分子レベル安定同位体比分析法"},{"@language":"en","@value":"Compound-specific isotope analysis (CSIA) by gas chromatograph/isotope ratio mass spectrometer (GC/IRMS)"},{"@language":"ja-Kana","@value":"ガスクロマトグラフ ドウイタイヒ シツリョウ ブンセキケイ ニ ヨル ブンシ レベル アンテイ ドウイタイヒ ブンセキホウ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680390832768","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"微少有機化合物の水素同位体比測定法"},{"@language":"en","@value":"Compound-specific stable hydrogen isotope analysis of small amount of organic compounds"},{"@language":"ja-Kana","@value":"ビショウ ユウキ カゴウブツ ノ スイソ ドウイタイヒ ソクテイホウ"}]},{"@id":"https://cir.nii.ac.jp/crid/1520572359393937536","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@value":"安定同位体利用技術 生態学指標としての安定同位体--アミノ酸の窒素同位体分析による新展開"},{"@language":"ja-Kana","@value":"アンテイ ドウイタイ リヨウ ギジュツ セイタイガク シヒョウ ト シテ ノ アンテイ ドウイタイ アミノサン ノ チッソ ドウイタイ ブンセキ ニ ヨル シン テンカイ"}]},{"@id":"https://cir.nii.ac.jp/crid/2051714792052381184","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Amino acid compositions in heated carbonaceous chondrites and their compound-specific nitrogen isotopic ratios"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/jssc.200600002"},{"@type":"CIA","@value":"80018958694"},{"@type":"CROSSREF","@value":"10.1016/j.orggeochem.2017.07.009_references_DOI_KwWeZeu27YxYHlvR6rqk1GxjHFn"},{"@type":"CROSSREF","@value":"10.1002/rcm.8170_references_DOI_KwWeZeu27YxYHlvR6rqk1GxjHFn"},{"@type":"CROSSREF","@value":"10.1002/lom3.10272_references_DOI_KwWeZeu27YxYHlvR6rqk1GxjHFn"},{"@type":"CROSSREF","@value":"10.1186/s40623-016-0382-8_references_DOI_KwWeZeu27YxYHlvR6rqk1GxjHFn"},{"@type":"CROSSREF","@value":"10.1007/s10337-022-04203-6_references_DOI_KwWeZeu27YxYHlvR6rqk1GxjHFn"},{"@type":"CROSSREF","@value":"10.6013/jbrewsocjapan.109.212_references_DOI_KwWeZeu27YxYHlvR6rqk1GxjHFn"}]}