{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137045166014720.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1042/cs20050207"}},{"identifier":{"@type":"URI","@value":"https://portlandpress.com/clinsci/article-pdf/110/4/409/437417/cs1100409.pdf"}}],"dc:title":[{"@value":"Physical activity, fitness and cardiovascular disease risk in adults: interactions with insulin resistance and obesity"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>There is a considerable body of evidence gathered from studies over the past half a century indicating that a high level of physical activity and a moderately high or high degree of cardiorespiratory fitness reduces the risk of CVD (cardiovascular disease). Recent data suggest that high levels of physical activity or fitness may be particularly beneficial to individuals with insulin-resistant conditions, such as the metabolic syndrome, Type II diabetes or obesity. These individuals, if unfit and sedentary, exhibit increased CVD risk, but their dose–response relationship for physical activity/fitness appears to be particularly steep such that, when they undertake high levels of activity (or have high fitness), their level of risk becomes closer to that of their normal weight or nondiabetic peers. This may be due to effects of physical activity in normalizing the metabolic dysfunction particularly associated with insulin-resistant conditions.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381137045166014721","@type":"Researcher","foaf:name":[{"@value":"Jason M. R. Gill"}],"jpcoar:affiliationName":[{"@value":"Institute of Diet, Exercise and Lifestyle (IDEAL), Institute of Biomedical and Life Sciences, West Medical Building, University of Glasgow, Glasgow G12 8QQ, U.K."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137045166014720","@type":"Researcher","foaf:name":[{"@value":"Dalia Malkova"}],"jpcoar:affiliationName":[{"@value":"Institute of Diet, Exercise and Lifestyle (IDEAL), Institute of Biomedical and Life Sciences, West Medical Building, University of Glasgow, Glasgow G12 8QQ, U.K."},{"@value":"Division of Developmental Medicine, University of Glasgow, Yorkhill Hospitals, Glasgow G3 8SJ, U.K."}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"01435221"},{"@type":"EISSN","@value":"14708736"}],"prism:publicationName":[{"@value":"Clinical Science"}],"dc:publisher":[{"@value":"Portland Press Ltd."}],"prism:publicationDate":"2006-03-15","prism:volume":"110","prism:number":"4","prism:startingPage":"409","prism:endingPage":"425"},"reviewed":"false","url":[{"@id":"https://portlandpress.com/clinsci/article-pdf/110/4/409/437417/cs1100409.pdf"}],"createdAt":"2006-03-15","modifiedAt":"2021-12-01","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1390001204454637184","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Marital Status and Cardiovascular Risk Factors among Middle-aged Japanese Male Workers: The High-risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study"},{"@value":"Marital Status and Cardiovascular Risk Factors among Middle‐aged Japanese Male Workers: The High‐risk and Population Strategy for Occupational Health Promotion (HIPOP‐OHP) Study"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679432280192","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Comparative Study of Lipids Extracted from Herring Roe Products and Fish Oil on Plasma Glucose and Adipocytokine Levels in ICR Aged Mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680196058112","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"データサイエンスから解明される世界の食用生物の多様性とヘルスケア"},{"@language":"en","@value":"Data Intensive Study of Accessibility of Edible Species and Healthcare Across the Globe"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1042/cs20050207"},{"@type":"CROSSREF","@value":"10.3136/fstr.14.25_references_DOI_1dr5V8KmofTg0mtKvlybRfBDlLu"},{"@type":"CROSSREF","@value":"10.1539/joh.l7158_references_DOI_1dr5V8KmofTg0mtKvlybRfBDlLu"},{"@type":"CROSSREF","@value":"10.1625/jcam.15.37_references_DOI_1dr5V8KmofTg0mtKvlybRfBDlLu"}]}