{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137045532547712.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1126/science.2845584"}},{"identifier":{"@type":"URI","@value":"https://www.science.org/doi/pdf/10.1126/science.2845584"}},{"identifier":{"@type":"NAID","@value":"80004324416"}}],"dc:title":[{"@value":"Mineralocorticoid Action: Target Tissue Specificity Is Enzyme, Not Receptor, Mediated"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Mineralocorticoid receptors, both when in tissue extracts and when recombinant-derived, have equal affinity for the physiological mineralocorticoid aldosterone and for the glucocorticoids cortisol and corticosterone, which circulate at much higher concentrations than aldosterone. Such receptors are found in physiological mineralocorticoid target tissues (kidney, parotid, and colon) and in nontarget tissues such as hippocampus and heart. In mineralocorticoid target tissues the receptors are selective for aldosterone in vivo because of the presence of the enzyme 11 β-hydroxy-steroid dehydrogenase, which converts cortisol and corticosterone, but not aldosterone, to their 11-keto analogs. These analogs cannot bind to mineralocorticoid receptors.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381137045532547715","@type":"Researcher","foaf:name":[{"@value":"John W. Funder"}],"jpcoar:affiliationName":[{"@value":"Medical Research Centre, Prince Henry's Hospital, Melbourne, Australia 3004."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137045532547713","@type":"Researcher","foaf:name":[{"@value":"Paul T. Pearce"}],"jpcoar:affiliationName":[{"@value":"Medical Research Centre, Prince Henry's Hospital, Melbourne, Australia 3004."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137045532547712","@type":"Researcher","foaf:name":[{"@value":"Robin Smith"}],"jpcoar:affiliationName":[{"@value":"Medical Research Centre, Prince Henry's Hospital, Melbourne, Australia 3004."}]},{"@id":"https://cir.nii.ac.jp/crid/1381137045532547714","@type":"Researcher","foaf:name":[{"@value":"A. Ian Smith"}],"jpcoar:affiliationName":[{"@value":"Medical Research Centre, Prince Henry's Hospital, Melbourne, Australia 3004."}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00368075"},{"@type":"EISSN","@value":"10959203"},{"@type":"PISSN","@value":"https://id.crossref.org/issn/00368075"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/00368075"}],"prism:publicationName":[{"@value":"Science"}],"dc:publisher":[{"@value":"American Association for the Advancement of Science (AAAS)"}],"prism:publicationDate":"1988-10-28","prism:volume":"242","prism:number":"4878","prism:startingPage":"583","prism:endingPage":"585"},"reviewed":"false","url":[{"@id":"https://www.science.org/doi/pdf/10.1126/science.2845584"}],"createdAt":"2006-10-05","modifiedAt":"2024-01-13","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050001202648866944","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Liquorice-induced hypokalaemia in patients treated with Yokukansan preparations: identification of the risk factors in a retrospective cohort study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004232001001472","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Mineralocorticoid receptor function in bone metabolism and its role in glucocorticoid-induced osteopenia"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004232548428800","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Construction of sensitive reporter assay yeasts for comprehensive detection of ligand activities of human corticosteroid receptors through inactivation of CWP and PDR genes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004234890455808","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Effects of mineralocorticoid receptor blockade on glucocorticoid-induced renal injury in adrenalectomized rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004237936200960","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor and NaCl transport mechanisms in the renal distal nephron"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004239460417792","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The Amphibious Mudskipper: A Unique Model Bridging the Gap of Central Actions of Osmoregulatory Hormones Between Terrestrial and Aquatic Vertebrates"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142766395520","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The Mineralocorticoid Receptor in Salt-Sensitive Hypertension and Renal Injury"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285707300465152","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A possible principal function of corticosteroid signaling that is conserved in vertebrate evolution: Lessons from receptor-knockout small fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285714487495808","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"‘Central’ Actions of Corticosteroid Signaling Suggested by Constitutive Knockout of Corticosteroid Receptors in Small Fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565168684878848","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Renal Dysfunction Induced by Kidney-Specific Gene Deletion of\n            <i>Hsd11b2</i>\n            as a Primary Cause of Salt-Dependent Hypertension"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567180120913920","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Wild‐type and specific mutant androgen receptor mediates transcription via 17β‐estradiol in sex hormone‐sensitive cancer cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567182206046592","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Development of suitable method for large-scale urinary glucocorticoid analysis by liquid chromatography–mass spectrometry"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567183617048576","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Electrolyte transport in the renal collecting duct and its regulation by the renin–angiotensin–aldosterone system"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846641048030592","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Corticosteroids stimulate the amphibious behavior in mudskipper: Potential role of mineralocorticoid receptors in teleost fish"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846642438488576","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The Role of Aldosterone in Obesity-Related Hypertension"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848655085544064","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Characterization of <i>Oryzias latipes</i> glucocorticoid receptors and their unique response to progestins"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848657444248576","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The effect of water loading on the urinary ratio of cortisone to cortisol in healthy subjects and a new approach to the evaluation of the ratio as an index for in vivo human 11β-hydroxysteroid dehydrogenase 2 activity"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848661362456192","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Atrial Natriuretic Peptide Locally Counteracts the Deleterious Effects of Cardiomyocyte Mineralocorticoid Receptor Activation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360850094099077376","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Two Mineralocorticoid Receptor–Mediated Mechanisms of Pendrin Activation in Distal Nephrons"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861707114591104","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Characteristics of psychiatric patients with hypokalemia after yokukansan administration: A retrospective study"}]},{"@id":"https://cir.nii.ac.jp/crid/1361975845368977024","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Postoperative renal impairment and longitudinal change in renal function after adrenalectomy in patients with Cushing's syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204260738048","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Inner Ear and Hormones."},{"@value":"内耳とホルモン"},{"@language":"ja-Kana","@value":"ナイジ ト ホルモン"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001206297618176","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The Role of 11.BETA.-Hydroxysteroid Dehydrogenases in the Cardiovascular System"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001206297833216","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Expression of 11.BETA.-Hydroxysteroid Dehydrogenase Type 1 in Alveolar Epithelial Cells in Rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001206303180800","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Hypothalamic-pituitary-adrenal axis activity is associated with the prevalence of chronic kidney disease in diabetic patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001206443321472","@type":"Article","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"内分泌性高血圧症：診断と治療の進歩　　ＩＩＩ．原発性アルドステロン症の類縁疾患　　１．Ａｐｐａｒｅｎｔ　Ｍｉｎｅｒａｌｏｃｏｒｔｉｃｏｉｄ　Ｅｘｃｅｓｓ症候群"},{"@value":"Apparent Mineralocorticoid Excess症候群"},{"@language":"ja-Kana","@value":"Apparent Mineralocorticoid Excess ショウコウグン"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679475264000","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Inhibition of 11.BETA.-Hydroxysteroid Dehydrogenase Improves Glucose Metabolism in Insulin Resistant Otsuka Long-Evans Tokushima Fatty Rats"},{"@value":"Inhibition of 11β-hydroxysteroid dehydrogenase improves glucose metabolism in insulin resistant Otsuka Long-Evans Tokushima Fatty rats"},{"@language":"ja-Kana","@value":"Inhibition of 11 v hydroxysteroid dehydrogenase improves glucose metabolism in insulin resistant Otsuka Long Evans Tokushima Fatty rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679695538560","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"11.BETA.-Hydroxysteroid Dehydrogenase Activity in Human Aortic Smooth Muscle Cells."}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679695856256","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Endocrine and Auto-Paracrine Factors in the Pathogenesis of Primary Hypertension."}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679877862528","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Immunolocalization of corticosteroid hormone receptors in the mechanoreceptors in rat oral tissues"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680021601280","@type":"Article","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Licorice Extract Does Not Impair the Male Reproductive Function of Rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681276104320","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Longer <i>HSD11B2</i> CA-repeat in impaired glucose tolerance and type 2 diabetes"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681413306368","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Two Cases of with Hyponatremia due to Hypoaldosteronism, accompanyed by Adult onset Still's Disease"},{"@language":"ja","@value":"成人Still病に対するプレドニゾロン長期投与中にアルドステロン分泌不全を伴う低Na血症を来した二例"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681421205376","@type":"Article","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"5) Renal Failure and Aldosterone"},{"@language":"ja","@value":"5）腎疾患とアルドステロン"},{"@value":"腎疾患とアルドステロン"},{"@language":"ja-Kana","@value":"ジンシッカン ト アルドステロン"}]},{"@id":"https://cir.nii.ac.jp/crid/1390851020849722368","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Pathology of Aldosterone Biosynthesis and its Action"}]},{"@id":"https://cir.nii.ac.jp/crid/1520290885483620480","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@value":"Regional Difference of 11β-Hydroxysteroid Dehydrogenase Activity in Quail oviduct"},{"@language":"ja-Kana","@value":"Regional Difference of 11 ベーターHydroxyst"}]},{"@id":"https://cir.nii.ac.jp/crid/1570291226047691392","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Aldosterone, hypertension and heart failure : insights from clinical trials"}]},{"@id":"https://cir.nii.ac.jp/crid/1570572700774774912","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Regulatory mechanism of \"K^+-recycling\" for Na^+-reabsorption in renal tubules"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854174944444672","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Alveolar Epithelial Cells in Rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854175157835648","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The Role of 11β-Hydroxysteroid Dehydrogenases in the Cardiovascular System"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854175470664448","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"うっ血性心不全と尿閉を合併した偽性アルドステロン症の1例"},{"@language":"en","@value":"PSEUDOALDOSTERONISM ASSOCIATED WITH CONGESTIVE HEART FAILURE AND URINARY RETENTION : A CASE REPORT"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854175813310336","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Regulation and dysregulation of epithelial Na^+ channels"}]},{"@id":"https://cir.nii.ac.jp/crid/1571135649340394240","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Distribution of glucocorticoid receptor immunoreactivity and mRNA in the rat brain: an immunohistochemical and in situ hybridization study"}]},{"@id":"https://cir.nii.ac.jp/crid/1571135651253319296","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Activation of the aldosterone/mineralocorticoid receptor system in chronic kidney disease and metabolic syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1571417124464561280","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Increased ACTH Levels Do not Alter Renal 11β- Hydroxysteroid Dehydrogenase Type 2 Gene Expression in the Sheep"}]},{"@id":"https://cir.nii.ac.jp/crid/1572261549955553792","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"In vivo induction of prostasin mRNA in colonic epithelial cells by dietary sodium depletion and aldosterone infusion in rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1572824499341654400","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"In vitro and in vivo immunocytochemistry for the distribution of mineralocorticoid receptor with the use of specific antibody"}]},{"@id":"https://cir.nii.ac.jp/crid/1573387450310778368","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Spironolactone Modulates Expressions of Cardiac Mineralocorticoid Receptor and 11β-Hydroxysteroid Dehydrogenase 2 and Prevents Ventricular Remodeling in Post-Infarct Rat Hearts"}]},{"@id":"https://cir.nii.ac.jp/crid/1573387450814504448","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Involvement of the bone morphogenetic protein system in endothelin- and aldosterone-induced cell proliferation of pulmonary arterial smooth muscle cells isolated from human patients with pulmonary arterial hypertension"}]},{"@id":"https://cir.nii.ac.jp/crid/2051996266980601600","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Activation of the aldosterone/mineralocorticoid receptor system in chronic kidney disease and metabolic syndrome"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1126/science.2845584"},{"@type":"CIA","@value":"80004324416"},{"@type":"CROSSREF","@value":"10.1007/s10157-010-0298-8_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1097/hjh.0b013e32834103a9_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1136/bmjopen-2016-014218_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1530/joe-16-0669_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.3389/fphys.2018.01112_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1538/expanim.57.11_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1248/jhs.57.378_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1016/j.steroids.2012.07.008_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1507/endocrj.ej12-0108_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.2169/naika.97.2171_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.2220/biomedres.25.35_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1507/endocrj.ej15-0360_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1681/asn.2020071041_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.3390/nu11030611_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1016/j.vascn.2015.06.001_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1507/endocrj.50.485_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1161/hypertensionaha.116.08966_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1002/jcp.24906_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1042/cs20180194_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.2169/naika.95.662_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1291/hypres.24.33_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1093/ajh/hpw003_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1002/jat.3020_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1161/circheartfailure.113.000885_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1507/endocrj.50.445_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1681/asn.2019080804_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1620/tjem.254.1_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1016/j.bbrc.2014.03.149_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1002/pcn5.76_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1016/j.physbeh.2011.06.002_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1016/j.jchromb.2017.04.031_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1111/iju.14205_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"},{"@type":"CROSSREF","@value":"10.1016/j.jsbmb.2018.02.011_references_DOI_U1v2eFxYbdUfw55hFfoqYB3C7jD"}]}