{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361137045991831040.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/ejoc.201600521"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fejoc.201600521"}},{"identifier":{"@type":"URI","@value":"https://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/ejoc.201600521"}}],"dc:title":[{"@value":"Preorganized Fluorescent Receptor for the Preferential Binding of the Glutarate Anion"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>A carbazolo[1,2‐<jats:italic>a</jats:italic>]carbazole‐2,11‐dicarboxamide has been synthesized and studied as a dicarboxylate anion receptor. The preorganized structure of this ligand affords a size‐selective response when a homologous series of dicarboxylates are analyzed. The structural correlation between the receptor and the different dianions was confirmed by <jats:sup>1</jats:sup>H NMR studies, and different binding modes were also studied by X‐ray crystal structure analysis. The fluorescent properties of the carbazolocarbazole unit give a ratiometric response for those anions that have the best size fit. During the recognition process, the selective signaling of the glutarate anion results in a switch in the fluorescence color between the free and bound species. The detection of glutarate metabolites is important for the diagnosis of glutaric aciduria.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380298341643959424","@type":"Researcher","foaf:name":[{"@value":"Miriam Más‐Montoya"}],"jpcoar:affiliationName":[{"@value":"Faculty of Chemistry University of Murcia Campus of Espinardo 30100 Murcia Spain"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137045991831041","@type":"Researcher","foaf:name":[{"@value":"David Curiel"}],"jpcoar:affiliationName":[{"@value":"Faculty of Chemistry University of Murcia Campus of Espinardo 30100 Murcia Spain"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137045991831042","@type":"Researcher","foaf:name":[{"@value":"Carmen Ramírez de Arellano"}],"jpcoar:affiliationName":[{"@value":"Department of Organic Chemistry Faculty of Pharmacy University of Valencia c/ Vicente Andres Estelles s/n 46100 Burjasot Valencia Spain"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137045991831043","@type":"Researcher","foaf:name":[{"@value":"Alberto Tárraga"}],"jpcoar:affiliationName":[{"@value":"Faculty of Chemistry University of Murcia Campus of Espinardo 30100 Murcia Spain"}]},{"@id":"https://cir.nii.ac.jp/crid/1381137045991831040","@type":"Researcher","foaf:name":[{"@value":"Pedro Molina"}],"jpcoar:affiliationName":[{"@value":"Faculty of Chemistry University of Murcia Campus of Espinardo 30100 Murcia Spain"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"1434193X"},{"@type":"EISSN","@value":"10990690"}],"prism:publicationName":[{"@value":"European Journal of Organic Chemistry"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2016-07-18","prism:volume":"2016","prism:number":"22","prism:startingPage":"3878","prism:endingPage":"3883"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fejoc.201600521"},{"@id":"https://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/ejoc.201600521"}],"createdAt":"2016-07-18","modifiedAt":"2025-10-15","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360017282222285312","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Highly-selective recognition of dicarboxylic acid using 9-(diphenylmethylene)fluorene-based diamidine"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576118830765184","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Carboxylic acid recognition of an N-ethyl-substituted diamidine having a diphenylnaphthalene unit in competing protic solvents"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857593805850880","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Carboxylic acid recognition of a tetraamidine having a tetraphenylethylene unit based on aggregation-induced emission"}]},{"@id":"https://cir.nii.ac.jp/crid/1360869856052216192","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Recognition of carboxylic acids and phosphonic acids using a 1,8-diphenylanthracene-based diguanidine in solution and solid states"}]},{"@id":"https://cir.nii.ac.jp/crid/1361412889559582848","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Efficient Synthesis, Structural Characterization, and Optical Properties of 6<i>H</i>‐Dibenzo[<i>b</i>,<i>h</i>]carbazole and Its Derivatives"}]},{"@id":"https://cir.nii.ac.jp/crid/2051433317038778880","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Naked-eye-detectable supramolecular sensing system for glutaric acid and isophthalic acid"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/ejoc.201600521"},{"@type":"CROSSREF","@value":"10.1016/j.tet.2022.133139_references_DOI_XsOKMgPwAWtirYZPKQYBrRorDSb"},{"@type":"CROSSREF","@value":"10.1246/bcsj.20220195_references_DOI_XsOKMgPwAWtirYZPKQYBrRorDSb"},{"@type":"CROSSREF","@value":"10.1016/j.tet.2021.132373_references_DOI_XsOKMgPwAWtirYZPKQYBrRorDSb"},{"@type":"CROSSREF","@value":"10.1016/j.tet.2021.132254_references_DOI_XsOKMgPwAWtirYZPKQYBrRorDSb"},{"@type":"CROSSREF","@value":"10.1016/j.tet.2024.134314_references_DOI_XsOKMgPwAWtirYZPKQYBrRorDSb"},{"@type":"CROSSREF","@value":"10.1002/ejoc.201900464_references_DOI_XsOKMgPwAWtirYZPKQYBrRorDSb"}]}