{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361418518806380928.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1128/cdli.12.2.361-362.2005"}},{"identifier":{"@type":"URI","@value":"https://journals.asm.org/doi/pdf/10.1128/CDLI.12.2.361-362.2005"}}],"dc:title":[{"@value":"Antibody Responses to Asian and American Genotypes of Dengue 2 Virus in Immunized Mice"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>ABSTRACT</jats:title>\n          <jats:p>The possibility of a correlation between dengue virus genotype groups and disease severity is currently under discussion. The objective of this investigation was to identify any immunogenic difference between the American and Asian dengue 2 virus genotypes through the study of antibody development (virus-binding immunoglobulin G and neutralizing antibodies) in mice. Differences in the neutralization pattern between the strains studied were observed, suggesting the presence of slight antigenic variations among them. The lack of recognition of one of the Asian genotype strains was remarkable.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381418518806380928","@type":"Researcher","foaf:name":[{"@value":"Lidice Bernardo"}],"jpcoar:affiliationName":[{"@value":"Virology Department, PAHO/WHO Collaborating Center for Viral Diseases, “Pedro Kourí” Tropical Medicine Institute, Autopista Novia del Mediodía, Havana, Cuba"}]},{"@id":"https://cir.nii.ac.jp/crid/1381418518806380930","@type":"Researcher","foaf:name":[{"@value":"Adriana Yndart"}],"jpcoar:affiliationName":[{"@value":"Virology Department, PAHO/WHO Collaborating Center for Viral Diseases, “Pedro Kourí” Tropical Medicine Institute, Autopista Novia del Mediodía, Havana, Cuba"}]},{"@id":"https://cir.nii.ac.jp/crid/1381418518806380929","@type":"Researcher","foaf:name":[{"@value":"Susana Vázquez"}],"jpcoar:affiliationName":[{"@value":"Virology Department, PAHO/WHO Collaborating Center for Viral Diseases, “Pedro Kourí” Tropical Medicine Institute, Autopista Novia del Mediodía, Havana, Cuba"}]},{"@id":"https://cir.nii.ac.jp/crid/1381418518806380931","@type":"Researcher","foaf:name":[{"@value":"Luis Morier"}],"jpcoar:affiliationName":[{"@value":"Virology Department, PAHO/WHO Collaborating Center for Viral Diseases, “Pedro Kourí” Tropical Medicine Institute, Autopista Novia del Mediodía, Havana, Cuba"}]},{"@id":"https://cir.nii.ac.jp/crid/1381418518806380800","@type":"Researcher","foaf:name":[{"@value":"María G. Guzmán"}],"jpcoar:affiliationName":[{"@value":"Virology Department, PAHO/WHO Collaborating Center for Viral Diseases, “Pedro Kourí” Tropical Medicine Institute, Autopista Novia del Mediodía, Havana, Cuba"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"15566811"},{"@type":"EISSN","@value":"1556679X"}],"prism:publicationName":[{"@value":"Clinical and Vaccine Immunology"}],"dc:publisher":[{"@value":"American Society for Microbiology"}],"prism:publicationDate":"2005-02","prism:volume":"12","prism:number":"2","prism:startingPage":"361","prism:endingPage":"362"},"reviewed":"false","dc:rights":["https://journals.asm.org/non-commercial-tdm-license"],"url":[{"@id":"https://journals.asm.org/doi/pdf/10.1128/CDLI.12.2.361-362.2005"}],"createdAt":"2005-02-07","modifiedAt":"2021-07-29","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Microbiology%20(medical)","dc:title":"Microbiology (medical)"},{"@id":"https://cir.nii.ac.jp/all?q=Clinical%20Biochemistry","dc:title":"Clinical Biochemistry"},{"@id":"https://cir.nii.ac.jp/all?q=Immunology","dc:title":"Immunology"},{"@id":"https://cir.nii.ac.jp/all?q=Immunology%20and%20Allergy","dc:title":"Immunology and Allergy"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050568772240586240","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Human antibody response to dengue virus: implications for dengue vaccine design"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1128/cdli.12.2.361-362.2005"},{"@type":"CROSSREF","@value":"10.1186/s41182-016-0004-y_references_DOI_F3XWWTAhN9zRgsaFRbUPxDmvD9y"}]}