{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361418521121535360.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1073/pnas.1212977109"}},{"identifier":{"@type":"URI","@value":"https://pnas.org/doi/pdf/10.1073/pnas.1212977109"}}],"dc:title":[{"@value":"Splice variant of the SND1 transcription factor is a dominant negative of SND1 members and their regulation in\n            <i>Populus trichocarpa</i>"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>\n            Secondary Wall-Associated NAC Domain 1s (SND1s) are transcription factors (TFs) known to activate a cascade of\n            <jats:italic>TF</jats:italic>\n            and pathway genes affecting secondary cell wall biosynthesis (xylogenesis) in\n            <jats:italic>Arabidopsis</jats:italic>\n            and poplars. Elevated SND1 transcriptional activation leads to ectopic xylogenesis and stunted growth. Nothing is known about the upstream regulators of\n            <jats:italic>SND1</jats:italic>\n            . Here we report the discovery of a stem-differentiating xylem (SDX)-specific alternative\n            <jats:italic>SND1</jats:italic>\n            splice variant,\n            <jats:italic>PtrSND1</jats:italic>\n            -\n            <jats:italic>A2</jats:italic>\n            <jats:sup>\n              <jats:italic>IR</jats:italic>\n            </jats:sup>\n            , that acts as a dominant negative of SND1 transcriptional network genes in\n            <jats:italic>Populus trichocarpa</jats:italic>\n            .\n            <jats:italic>PtrSND1</jats:italic>\n            -\n            <jats:italic>A2</jats:italic>\n            <jats:sup>\n              <jats:italic>IR</jats:italic>\n            </jats:sup>\n            derives from\n            <jats:italic>PtrSND1-A2</jats:italic>\n            , one of the four fully spliced\n            <jats:italic>PtrSND1</jats:italic>\n            gene family members (\n            <jats:italic>PtrSND1</jats:italic>\n            -\n            <jats:italic>A1</jats:italic>\n            , -\n            <jats:italic>A2</jats:italic>\n            , -\n            <jats:italic>B1</jats:italic>\n            , and -\n            <jats:italic>B2</jats:italic>\n            ). Each full-size PtrSND1 activates its own gene, and all four full-size members activate a common\n            <jats:italic>MYB</jats:italic>\n            gene (\n            <jats:italic>PtrMYB021</jats:italic>\n            ). PtrSND1-A2\n            <jats:sup>IR</jats:sup>\n            represses the expression of its\n            <jats:italic>PtrSND1</jats:italic>\n            member genes and\n            <jats:italic>PtrMYB021</jats:italic>\n            . Repression of the autoregulation of a TF family by its only splice variant has not been previously reported in plants. PtrSND1-A2\n            <jats:sup>IR</jats:sup>\n            lacks DNA binding and transactivation abilities but retains dimerization capability. PtrSND1-A2\n            <jats:sup>IR</jats:sup>\n            is localized exclusively in cytoplasmic foci. In the presence of any full-size PtrSND1 member, PtrSND1-A2\n            <jats:sup>IR</jats:sup>\n            is translocated into the nucleus exclusively as a heterodimeric partner with full-size PtrSND1s. Our findings are consistent with a model in which the translocated PtrSND1-A2\n            <jats:sup>IR</jats:sup>\n            lacking DNA-binding and transactivating abilities can disrupt the function of full-size PtrSND1s, making them nonproductive through heterodimerization, and thereby modulating the SND1 transcriptional network. PtrSND1-A2\n            <jats:sup>IR</jats:sup>\n            may contribute to transcriptional homeostasis to avoid deleterious effects on xylogenesis and plant growth.\n          </jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380013246454003584","@type":"Researcher","foaf:name":[{"@value":"Quanzi Li"}],"jpcoar:affiliationName":[{"@value":"Forest Biotechnology Group, Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695; and"}]},{"@id":"https://cir.nii.ac.jp/crid/1380013246454003587","@type":"Researcher","foaf:name":[{"@value":"Ying-Chung Lin"}],"jpcoar:affiliationName":[{"@value":"Forest Biotechnology Group, Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695; and"}]},{"@id":"https://cir.nii.ac.jp/crid/1380013246454003586","@type":"Researcher","foaf:name":[{"@value":"Ying-Hsuan Sun"}],"jpcoar:affiliationName":[{"@value":"Forest Biotechnology Group, Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695; and"}]},{"@id":"https://cir.nii.ac.jp/crid/1380013246454003591","@type":"Researcher","foaf:name":[{"@value":"Jian Song"}],"jpcoar:affiliationName":[{"@value":"Forest Biotechnology Group, Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695; and"}]},{"@id":"https://cir.nii.ac.jp/crid/1380013246454003585","@type":"Researcher","foaf:name":[{"@value":"Hao Chen"}],"jpcoar:affiliationName":[{"@value":"Forest Biotechnology Group, Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695; and"}]},{"@id":"https://cir.nii.ac.jp/crid/1380013246454003588","@type":"Researcher","foaf:name":[{"@value":"Xing-Hai Zhang"}],"jpcoar:affiliationName":[{"@value":"Department of Biological Sciences, Florida Atlantic University, Boca Raton, FL 33431"}]},{"@id":"https://cir.nii.ac.jp/crid/1380013246454003589","@type":"Researcher","foaf:name":[{"@value":"Ronald R. Sederoff"}],"jpcoar:affiliationName":[{"@value":"Forest Biotechnology Group, Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695; and"}]},{"@id":"https://cir.nii.ac.jp/crid/1380013246454003590","@type":"Researcher","foaf:name":[{"@value":"Vincent L. Chiang"}],"jpcoar:affiliationName":[{"@value":"Forest Biotechnology Group, Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695; and"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00278424"},{"@type":"EISSN","@value":"10916490"}],"prism:publicationName":[{"@value":"Proceedings of the National Academy of Sciences"}],"dc:publisher":[{"@value":"Proceedings of the National Academy of Sciences"}],"prism:publicationDate":"2012-08-22","prism:volume":"109","prism:number":"36","prism:startingPage":"14699","prism:endingPage":"14704"},"reviewed":"false","url":[{"@id":"https://pnas.org/doi/pdf/10.1073/pnas.1212977109"}],"createdAt":"2012-08-23","modifiedAt":"2022-04-13","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050009640091045760","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Identifying transcription factors that reduce wood recalcitrance and improve enzymatic degradation of xylem cell wall in Populus"}]},{"@id":"https://cir.nii.ac.jp/crid/1050287297269461376","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"MYB-mediated regulation of lignin biosynthesis in grasses"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013168786302208","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Prior secondary cell wall formation is required for gelatinous layer deposition and posture control in gravi‐stimulated aspen"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285708509317248","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Wood reinforcement of poplar by rice NAC transcription factor"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567184719351552","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Populus NST/SND orthologs are key regulators of secondary cell wall formation in wood fibers, phloem fibers and xylem ray parenchyma cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846645591549440","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"NAC-MYB-based transcriptional regulation of secondary cell wall biosynthesis in land plants"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204326864768","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Continuous expression of genes for xylem cysteine peptidases in long-lived ray parenchyma cells in <i>Populus</i>"},{"@value":"Continuous expression of genes for xylem cysteine peptidases in long-lived ray parenchyma cells in Populus"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1073/pnas.1212977109"},{"@type":"CROSSREF","@value":"10.1038/s41598-020-78781-6_references_DOI_DixNS9CRSPBml2oocJpeHOzAJ4K"},{"@type":"CROSSREF","@value":"10.1111/tpj.15466_references_DOI_DixNS9CRSPBml2oocJpeHOzAJ4K"},{"@type":"CROSSREF","@value":"10.1038/srep19925_references_DOI_DixNS9CRSPBml2oocJpeHOzAJ4K"},{"@type":"CROSSREF","@value":"10.1016/j.cpb.2020.100174_references_DOI_DixNS9CRSPBml2oocJpeHOzAJ4K"},{"@type":"CROSSREF","@value":"10.1093/treephys/tpz004_references_DOI_DixNS9CRSPBml2oocJpeHOzAJ4K"},{"@type":"CROSSREF","@value":"10.3389/fpls.2015.00288_references_DOI_DixNS9CRSPBml2oocJpeHOzAJ4K"},{"@type":"CROSSREF","@value":"10.5511/plantbiotechnology.14.1208a_references_DOI_DixNS9CRSPBml2oocJpeHOzAJ4K"}]}