Vancomycin Therapeutic Guidelines: A Summary of Consensus Recommendations from the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists

  • Michael J. Rybak
    Anti-Infective Research Laboratory, Department of Pharmacy Practice, College of Pharmacy & Health Sciences, and Detroit Receiving Hospital & University Health Center, Detroit, Michigan
  • Ben M. Lomaestro
    Albany Medical Center, Albany, New York
  • John C. Rotscahfer
    Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis
  • Robert C. Moellering
    Shields Warren-Mallinckrodt Medical Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
  • Willam A. Craig
    University of Wisconsin School of Medicine and Public Health, Madison
  • Marianne Billeter
    Oshsner Medical Centers and Department of Infectious Diseases, Oschsner Health System, New Orleans, Louisiana
  • Joseph R. Dalovisio
    Department of Infectious Diseases, Oschsner Health System, New Orleans, Louisiana
  • Donald P. Levine
    Detroit Receiving Hospital & University Health Center, Detroit, Michigan

説明

<jats:title>Abstract</jats:title> <jats:p>Practice guidelines for therapeutic monitoring of vancomycin treatment for Staphylococcus aureus infection in adult patients were reviewed by an expert panel of the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists. A literature review of existing evidence regarding vancomycin dosing and monitoring of serum concentrations, in addition to patient outcomes combined with expert opinion regarding the drug's pharmacokinetic, pharmacodynamic, and safety record, resulted in new recommendations for targeting and adjustment of vancomycin therapy.</jats:p>

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