Vascular Responsiveness and Body Fluid Status in Patients on Chronic Hemodialysis

M. Tajiri, Y. Aizawa, S. Sakai, K. Imai, Y. Hirasawa

doi:10.3109/08860228009065340

Vascular Responsiveness and Body Fluid Status in Patients on Chronic Hemodialysis

DOI Web Site PubMed 被引用文献1件

書誌事項

公開日: 1980-01

DOI

10.3109/08860228009065340

公開者: Informa UK Limited

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説明

The vascular responsiveness and the body fluid distribution were studied in 5 hypotensive and 11 normotensive patients on long-term hemodialysis. A diminished vascular responsiveness to intravenously infused norepinephrine or angiotensin II was found in uremic patients, especially in the hypotensive group. A slightly larger, but non-significant circulating blood volume (CBV) and a less extracellular fluid volume (ECF) was found in the hypotensive group as compared with those of the normotensive group. These results suggest that with autonomic nervous dysfunction, such a diminution of vascular responsiveness may be an another factor responsible for the development of hypotension.