{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699993791880320.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1159/000255973"}},{"identifier":{"@type":"URI","@value":"https://www.karger.com/Article/Pdf/255973"}}],"dc:title":[{"@value":"Stroke Associated with Atrial Fibrillation – Incidence and Early Outcomes in the North Dublin Population Stroke Study"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p><i>Background:</i> Prospective population-based studies are important to accurately determine the incidence and characteristics of stroke associated with atrial fibrillation (AF), while avoiding selection bias which may complicate hospital-based studies. <i>Methods:</i> We investigated AF-associated stroke within the North Dublin Population Stroke Study, a prospective cohort study of stroke/transient ischaemic attack in 294,592 individuals, according to recommended criteria for rigorous stroke epidemiological studies. <i>Results:</i> Of 568 stroke patients ascertained in the first year, 31.2% (177/568) were associated with AF (90.4%, i.e. 160/177 ischaemic infarcts). The crude incidence rate of all AF-associated stroke was 60/100,000 person-years (95% CI = 52–70). Prior stroke was almost twice as common in AF compared to non-AF groups (21.9 vs. 12.8%, p = 0.01). The frequency of AF progressively increased across ischaemic stroke patients stratified by increasing stroke severity (NIHSS 0–4, 29.7%; 5–9, 38.1%; 10–14, 43.8%; ≥15, 53.3%, p < 0.0001). The 90-day trajectory of recovery of AF-associated stroke was identical to that of non-AF stroke, but Rankin scores in AF stroke remained higher at 7, 28 and 90 days (p < 0.001 for all). <i>Discussion:</i> AF-associated stroke occurred in one third of all patients and was associated with a distinct profile of recurrent, severe and disabling stroke. Targeted strategies to increase anticoagulation rates may provide a substantial benefit to prevent severe disabling stroke at a population level.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699993791880449","@type":"Researcher","foaf:name":[{"@value":"Niamh Hannon"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880456","@type":"Researcher","foaf:name":[{"@value":"Orla Sheehan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880324","@type":"Researcher","foaf:name":[{"@value":"Lisa Kelly"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880454","@type":"Researcher","foaf:name":[{"@value":"Michael Marnane"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880451","@type":"Researcher","foaf:name":[{"@value":"Aine Merwick"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880320","@type":"Researcher","foaf:name":[{"@value":"Alan Moore"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880323","@type":"Researcher","foaf:name":[{"@value":"Lorraine Kyne"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880458","@type":"Researcher","foaf:name":[{"@value":"Joseph Duggan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880457","@type":"Researcher","foaf:name":[{"@value":"Joan Moroney"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880321","@type":"Researcher","foaf:name":[{"@value":"Patricia M.E. McCormack"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880322","@type":"Researcher","foaf:name":[{"@value":"Leslie Daly"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880452","@type":"Researcher","foaf:name":[{"@value":"Nicola Fitz-Simon"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880450","@type":"Researcher","foaf:name":[{"@value":"Dawn Harris"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880325","@type":"Researcher","foaf:name":[{"@value":"Gillian Horgan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880453","@type":"Researcher","foaf:name":[{"@value":"Emma B. Williams"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880448","@type":"Researcher","foaf:name":[{"@value":"Karen L. Furie"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699993791880455","@type":"Researcher","foaf:name":[{"@value":"Peter J. Kelly"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"10159770"},{"@type":"EISSN","@value":"14219786"}],"prism:publicationName":[{"@value":"Cerebrovascular Diseases"}],"dc:publisher":[{"@value":"S. Karger AG"}],"prism:publicationDate":"2009-11-05","prism:volume":"29","prism:number":"1","prism:startingPage":"43","prism:endingPage":"49"},"reviewed":"false","dc:rights":["https://www.karger.com/Services/SiteLicenses","https://www.karger.com/Services/SiteLicenses"],"url":[{"@id":"https://www.karger.com/Article/Pdf/255973"}],"createdAt":"2009-11-09","modifiedAt":"2025-04-23","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360298755646772096","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Diagnosis of Atrial Fibrillation Using Machine Learning With Wearable Devices After Cardiac Surgery: Algorithm Development Study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360572092526788096","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Use of a Smart Watch for Early Detection of Paroxysmal Atrial Fibrillation: Validation Study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360585257125439872","@type":"Article","resourceType":"preprint","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Use of a Smart Watch for Early Detection of Paroxysmal Atrial Fibrillation: Validation Study (Preprint)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857593720120320","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Reexamination of the Embolic Stroke of Undetermined Source Concept"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857593812602496","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Ischemic Stroke Risk Assessment by Multiscale Entropy Analysis of Heart Rate Variability in Patients with Persistent Atrial Fibrillation"}]},{"@id":"https://cir.nii.ac.jp/crid/1361412896346646784","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Searching for Atrial Fibrillation Poststroke"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205225090816","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Improvement of Predictive Value for Thromboembolic Risk by Incorporating Left Atrial Functional Parameters in the CHADS2 and CHA2DS2-VASc Scores"},{"@value":"Errata: Improvement of Predictive Value for Thromboembolic Risk by Incorporating Left Atrial Functional Parameters in the CHADS2 and CHA2DS2-VASc Scores"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001288039161344","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Two-Year Outcomes of Anticoagulation for Acute Ischemic Stroke With Nonvalvular Atrial Fibrillation　― SAMURAI-NVAF Study ―"},{"@value":"Two-year outcomes of anticoagulation for acute ischemic stroke with nonvalvular atrial fibrillation—SAMURAI-NVAF Study"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680084275968","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Comparison of the 2MACE and TIMI-AF Scores for Composite Clinical Outcomes in Anticoagulated Atrial Fibrillation Patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1390870142290793856","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"I．不整脈の検知（検脈，ホルター心電図，携帯心電計など）"},{"@language":"en","@value":"I. 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