{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699994020695552.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1021/jm801514w"}},{"identifier":{"@type":"URI","@value":"https://pubs.acs.org/doi/pdf/10.1021/jm801514w"}}],"dc:title":[{"@value":"Novel Chemical Space Exploration via Natural Products"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699994020695553","@type":"Researcher","foaf:name":[{"@value":"Josefin Rosén"}],"jpcoar:affiliationName":[{"@value":"Department of Medicinal Chemistry, Division of Pharmacognosy, BMC, Uppsala University, Box 574, S-751 23 Uppsala, Sweden, Pharmnovo Inc., Sahlgrenska Science Park, S-413 46 Gothenburg, Sweden, DECS Global Compound Sciences, AstraZeneca R&D, S-431 83 Mölndal, Sweden, and Division of Biocomputing, MSC11 6145, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994020695556","@type":"Researcher","foaf:name":[{"@value":"Johan Gottfries"}],"jpcoar:affiliationName":[{"@value":"Department of Medicinal Chemistry, Division of Pharmacognosy, BMC, Uppsala University, Box 574, S-751 23 Uppsala, Sweden, Pharmnovo Inc., Sahlgrenska Science Park, S-413 46 Gothenburg, Sweden, DECS Global Compound Sciences, AstraZeneca R&D, S-431 83 Mölndal, Sweden, and Division of Biocomputing, MSC11 6145, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994020695555","@type":"Researcher","foaf:name":[{"@value":"Sorel Muresan"}],"jpcoar:affiliationName":[{"@value":"Department of Medicinal Chemistry, Division of Pharmacognosy, BMC, Uppsala University, Box 574, S-751 23 Uppsala, Sweden, Pharmnovo Inc., Sahlgrenska Science Park, S-413 46 Gothenburg, Sweden, DECS Global Compound Sciences, AstraZeneca R&D, S-431 83 Mölndal, Sweden, and Division of Biocomputing, MSC11 6145, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994020695554","@type":"Researcher","foaf:name":[{"@value":"Anders Backlund"}],"jpcoar:affiliationName":[{"@value":"Department of Medicinal Chemistry, Division of Pharmacognosy, BMC, Uppsala University, Box 574, S-751 23 Uppsala, Sweden, Pharmnovo Inc., Sahlgrenska Science Park, S-413 46 Gothenburg, Sweden, DECS Global Compound Sciences, AstraZeneca R&D, S-431 83 Mölndal, Sweden, and Division of Biocomputing, MSC11 6145, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994020695552","@type":"Researcher","foaf:name":[{"@value":"Tudor I. Oprea"}],"jpcoar:affiliationName":[{"@value":"Department of Medicinal Chemistry, Division of Pharmacognosy, BMC, Uppsala University, Box 574, S-751 23 Uppsala, Sweden, Pharmnovo Inc., Sahlgrenska Science Park, S-413 46 Gothenburg, Sweden, DECS Global Compound Sciences, AstraZeneca R&D, S-431 83 Mölndal, Sweden, and Division of Biocomputing, MSC11 6145, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00222623"},{"@type":"EISSN","@value":"15204804"}],"prism:publicationName":[{"@value":"Journal of Medicinal Chemistry"}],"dc:publisher":[{"@value":"American Chemical Society (ACS)"}],"prism:publicationDate":"2009-03-06","prism:volume":"52","prism:number":"7","prism:startingPage":"1953","prism:endingPage":"1962"},"reviewed":"false","url":[{"@id":"https://pubs.acs.org/doi/pdf/10.1021/jm801514w"}],"createdAt":"2009-03-06","modifiedAt":"2025-02-08","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050287462762993152","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones."}]},{"@id":"https://cir.nii.ac.jp/crid/1360565166754643712","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Use of a biosynthetic intermediate to explore the chemical diversity of pseudo-natural fungal polyketides"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857593704328192","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Thermal Proteome Profiling Reveals Glutathione Peroxidase 4 as the Target of the Autophagy Inducer Conophylline"}]},{"@id":"https://cir.nii.ac.jp/crid/1390006131279629440","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Synthetic Biology Based Construction of Fungal Diterpenoid Pyrone Library"},{"@language":"ja","@value":"天然物の合成生物学研究を基盤とする糸状菌ジテルペノイドピロンライブラリーの構築"},{"@language":"ja-Kana","@value":"テンネンブツ ノ ゴウセイ セイブツガク ケンキュウ オ キバン ト スル シジョウキン ジテルペノイドピロンライブラリー ノ コウチク"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1021/jm801514w"},{"@type":"CROSSREF","@value":"10.5059/yukigoseikyokaishi.79.322_references_DOI_BqxQGReZ0MGiyk4dFQE9KevfIRt"},{"@type":"CROSSREF","@value":"10.1038/nchem.2308_references_DOI_BqxQGReZ0MGiyk4dFQE9KevfIRt"},{"@type":"CROSSREF","@value":"10.1038/s41467-020-15664-4_references_DOI_BqxQGReZ0MGiyk4dFQE9KevfIRt"},{"@type":"CROSSREF","@value":"10.1124/molpharm.121.000243_references_DOI_BqxQGReZ0MGiyk4dFQE9KevfIRt"}]}